[Methods of tissue extraction in laparoscopy].
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Biomedical subjects
Publications and source records attributed to K Shtereva.
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The paper presents the first cases of laparoscopic-assisted vaginal hysterectomy and laparoscopic hysterectomy with removal of the uterus through the vagina performed in Bulgaria as well as the experience gained by the team from II gynaecology clinic at State University Hospital "Maĭchin dom" in Sofia from seven patients operated on by these techniques. The indications, the conditions and the implemented technique with its advantages and difficulties are described. The procedures are associated with less trauma and blood loss than abdominal surgery and are followed by a very smooth postoperative period which is very well tolerated by the patients. No intraoperative complications occurred. The postoperative period was free of any problems in 5 of the patients while in two there were minor complications. Marked shortening of the duration of the procedures is achieved with the initial experience.
The aim of the study is to determine the concentration of blood serum zinc of women with ovarian tumors. The patients included in the study are as follows: 15 women with benign ovarian cysts, 5 with endometrial cysts and 5 with ovarian carcinoma. The control group consists of 157 healthy women whose serum zinc concentration was 13.50 +/- 2.60 mmol/L. We could not demonstrate a significant difference in serum zinc concentration of different groups: benign cysts, endometrial cysts and ovarian carcinoma in comparison control group.
The article presents the results of a comparative study on the efficacy of perioperative prophylaxis with cefalosporins in abdominal gynaecological operations. A total of 155 women meeting certain inclusion criteria were operated on and were randomly assigned to one of the following regimens: Cefoxitin 3 x 1 g--14 subjects, Cefotetan 2 x 1 g--43 subjects, Cefalotin 3 x 2 g for 24 hours--27 subjects, Cefalotin 3 x 2 g for 72 hours--41 subjects and a control group of 30 subjects without prophylaxis. The course of the postoperative period, the hospital stay and the average costs in each group were assessed and compared. None of patients receiving any prophylaxis developed infectious complications, while such complications occurred in 10% of the control without prophylaxis. The authors conclude that antibiotic prophylaxis effectively prevent the infectious complications and shortens the postoperative hospital stay. Despite its narrower anti-bacterial spectrum Cefalotin is not inferior in its efficacy to the second and the third-generation cefalosporins. While providing equal effect, the 24-hours Cefalotin regimen is from 2.8 to 4.9 times cheaper then the other prophylaxis regimens and is twice cheaper than the no-prophylaxis regimen. The longer 72-hours Cefalotin scheme shows no advantages to the 24-hours one but almost triples the expenses. Additional antibacterial treatment in the postoperative period needs more precise indications since unequivocal reasons for its administration are missing in a number of cases.
The study presents the results from the use of cefotetan for perioperative prophylaxis in 43 gynaecology patients compared with 29 controls without perioperative antibiotic prophylaxis with similar diseases and operations. Both groups show equal percentage of the cases with smooth postoperative period (70 and 72% respectively). 13 of the patients on cefotetan prophylaxis received additional antibiotic treatment (9 because of temperature up to 37.5 degrees and 4 because of temperature from 37.6 to 38.5 degrees). Mo major infections postoperative complications occurred among the patients on cefotetan prophylaxis. 8 of the non-prophylacted patients needed antibiotic treatment postoperatively including 4 with temperature above 38.5 degrees. Two infections of the operative wounds also occurred in the same group. The conclusion is that cefotetan effectively prevents the major infection postoperative complications in gynaecology. The administration of additional antibiotic treatment is most often not warranted.
During the period from January 1985 until May 1990, 56 pregnant women with malformed uterus were observed for the clinical curse of pregnancy: 22 women in the first, 26 in the second and 8 in the third trimester. The diagnosis was made by complex investigations: vaginal examination--in 48 cases, ultrasound examination-in 51 cases, previous hysterosalpingography--in 14 cases. In 17 women the performance of a cerclage was needed. In 17 women a hormonal treatment with gravibinon was applied. The results prove the reliability and validity of ultrasound examination, especially through the second trimester of pregnancy and the need of adequate hormonal (gravibinon) and operative treatment (cerclage).
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It is the purpose of the study to outline the superiorities of combined anesthesia in 100 patients undergoing orthopaedic (25 cases) and orthopaedic surgery (75 cases) interventions. The average duration of the operation is 90 +/- 25 min, performed under continuous peripheral (40 patients) and central (60 patients) nerve block, using Propofol against the background of continuous i.v. infusion and spontaneous ventilation. Nerve block is done according to routinely adopted techniques. The initial infusion rate for propofol (Diprivan) is 5 +/- 1.3 mg/kg/h, followed by infusional rate securing sedation II-III degree according to Ramsey's scale (mean 4 +/- 1.2 mg/kg/h). In 92 per cent of patients the sedation level is estimated as very good. In 8 per cent switching over to TIVA (total intravenous anesthesia) is necessitated because of the incomplete nerve block. No cases of hypotension or other essential secondary effects are recorded. Subjectively the anesthesiological technique is accepted as very good by most of the patients.
The study discusses the frequency of operative obstetric deliveries (cesarean section, forceps extraction and vacuum extraction) over a period of 18 years from 1976 till 1993. A total of 100,545 deliveries with 100,192 livebirths took place during this period with a decrease of the annual number of deliveries in the last years. The frequency of the various kinds of operative deliveries shows different tendencies. The frequency of cesarean section has increased from 4.87 per cent in 1976 to 19.58 per cent in 1993, this increase being particularly marked during the last 6 years. Meanwhile the vaginal operative deliveries have decreased their frequency. The decrease of forceps extraction is from 4.33 to 2.22 per cent (steadily about 2 per cent during the last years). The frequency of vacuum extraction has dropped from 1.89 per cent to 0 by the end of the 1980 and the beginning of the 1990. The tendencies of the development of obstetric operations are analysed as well as their influence on perinatal outcome.
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The larger usage of inducing ovulation drugs in the last decade brought to more frequent multiple pregnancies. The authors describe triplet pregnancy after hetero-insemination and ovaries stimulation which ended the birth (by Cesarean section) of three alive and healthy babies. The triplet pregnancy is high-risky. More often hypertension anaemia and postpartum haemorrhage are met. The most important complication anyway is the preterm delivery which shows as a result unfavourable perinatal outcome. The question about the effectiveness of the prophylactic cerclage and the prophylactic tocolysis is discussed. The general opinion is that there is a higher rate perinatal death for the second and the third fetus.
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