Biomedical subjects

K Steven

Publications and source records attributed to K Steven.

81 records · Page 5Linked to original sources

PubMed1978

Polyglycolic acid versus chromic catgut in bladder surgery.

The clinical importance of calcified deposits on sutures in bladder surgery was evaluated in a blind paired randomised trial of 3/0 chromic catgut versus polyglycolic acid 3/0. Cystoscopy with photographic recording was performed 8 weeks after operation in 40 patients without and 8 patients with previous or present bladder stones. None had visible calcified deposits at that time and sutures were only visible in 1 patient from each of the 2 groups without bladder stones. It was concluded that neither chromic catgut nor polyglycolic acid sutures carry any significant risk of bladder stone formation, whether infection is present or not; the conclusion includes both patients with and without previous bladder stones, but is less firm in the former because of the small number of patients studied.

Bacteriuria↗

PubMed1977

Angiotensin II induced reduction of peritubular capillary diameter in the rat kidney.

Large peritubular capillaries were infused consecutively (20 nl-min-1) in random sequence with isotonic saline and angiotensin II (20-80 ng-ml-1). The diameters of the infused capillaries were measured, without knowledge of the infusate used, from colour photographs of the infused area. Angiotensin II induced a significant (p less than 0.001) decrease in capillary diameter (delta = 1.2 +/- 0.2 (SE) micron and delta = 2.1 +/- 0.2 (SE) micron with 20 ng-ml-1 and 80 ng-ml-1 angiotensin II infusates, respectively). This decrease was shown to be independent of external tubular compression: separate experiments in which the surrounding tubules were collapsed by injection of oil blocks yielded similar results. The possibility that the observed reduction in diameter was caused by an angiotensin II induced change in capillary permeability to the staining solution was excluded, since the angiotensin II effect was unchanged when fluorescent dextran (mol. wt. 150 000) was substituted for lissamin green. These experiments indicate that peritubular capillaries contract actively when infused with angiotensin II.

Angiotensin II↗

PubMed1977