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K Swarup

Publications and source records attributed to K Swarup.

At least 19 recordsLinked to original sources

Dose-dependent vitamin D3, 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3-induced hypercalcemia and hyperphosphatemia, and the correlative changes in the activity of ultimobranchial and parathyroid glands of the toad, Bufo andersoni Boulenger.

Vitamin D3, 25(OH) vitamin D3 and 1,25 (OH)2D3 were administered daily to unfed male Bufo andersoni for 15 days which resulted in a significant hypercalcemia and hyperphosphatemia in a dose-dependent fashion. 1,25(OH)2D3 is more potent than the other metabolites. The treatment activated ultimobranchial gland but induced degenerative changes in parathyroid of the toads.

Animals

Seasonal changes in the serum calcium level and prolactin cells of Clarias batrachus in relation to the reproductive cycle.

The female specimens of Clarias batrachus show marked seasonal changes in serum calcium level and prolactin cells in relation to the ovarian cycle. The serum calcium level records the maximum value during the prespawning phase whereas, the prolactin cells show minimum activity during this phase. Thus, there is an inverse correlation between the serum calcium level and prolactin cells during the annual ovarian cycle. In male specimens there is no change in the serum calcium level and prolactin cells in relation to the testicular cycle.

Animals

Structure and behaviour of ultimobranchial gland in response to vitamin D3--induced hypercalcemia in male Clarias batrachus.

Hypercalcemia was induced in Clarias batrachus by treating them with vitamin D3 (5,000 I.U./100 g body wt.) and/or 0.5% solution of CaCl2. The animals were killed on 1st, 3rd, 5th, 9th, 13th and 17th days after the initiation of the experiment. Histological preparations of the ultimobranchial gland (UBG) were made. The gland exhibits nuclear hypertrophy, hyperplasia and loss of staining response corresponding to the rise in serum calcium levels. At later intervals, the UBG shows exhaustion and degeneration which is evident from vacuolization and nuclear shrinkage of the ultimobranchial cells after day 13 in groups B and C and day 9 in group D.

Animals

Effect of calcitonin on calcitonin cells, parathyroid glands and serum electrolytes in the house shrew (Suncus murinus).

Porcine calcitonin (CT) (0.5 MRC unit daily) was administered intraperitoneally to house shrews, Suncus murinus, for 42 days. The changes in serum calcium and phosphate levels as well as the light microscopical alterations of the parathyroid and calcitonin cells (C cells) between the 1st and 42nd day of treatment were recorded. The serum calcium level shows a fall up to the 7th day of treatment and thereafter it increases to normal values. The hypophosphataemic effect of CT increases progressively throughout the experiment continuing even after the loss of the hypocalcaemic effect. CT administration inhibits the release of secretory granules of C cells up to 21 days. Hyperplasia and degranulation of C cells is observed at 28, 35 and 42 days of treatment. C cells with collapsed membrane are also encountered in the lumina of the thyroid follicles. From the 28th day onwards the parathyroid chief cells of treated animals show hypertrophy and loss of staining reaction.

Animals

Morphology and distribution of calcitonin cells in the house shrew, Suncus murinus.

The thyroparathyroid complex of house shrews was cut into serial sections. For demonstration of calcitonin cells (C cells) the sections were stained by HE, PAS/haematoxylin, Heidenhain's iron haematoxylin, Mallory's aniline blue, toluidine blue, Davenport's silver impregnation and lead haematoxylin. The C cells are oval to slender in shape and are distributed unevenly (totally lacking from the peripheral, cranial, caudal and isthmus region). They are also encountered in the internal parathyroid gland.

Animals