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Biomedical subjects

K Taguchi

Publications and source records attributed to K Taguchi.

At least 145 records · Page 8Linked to original sources
PubMed1978

Flow control in prolonged ventricular bypass and clinical application in 15 patients.

Long-term experiments employing left ventricular or biventricular bypass with local heparinization and blood filtration for up to 48 days was conducted in 51 calves at different flow rates. The principle of flow control obtained was applied to 15 patients in critical cardiac states. An avcothanized extracorporeal circuit consisted of heparin and protamine microperfusion lines, Pall filter, and nonpulsatile pump. Bypass with flow rates at 30--40% of cardiac output was conducted between 3 and 48 days. Survival was obtained in 34 of 36 calves. Bypass with flow rates at 60--80% of cardiac output was associated with 6 deaths in the 10 calves who underwent the procedure. Bypass with flow rates over 90% of cardiac output was often technically difficult and only 2 of 5 calves survived. Hemodynamic changes correlated well with the above results. In clinical cases flow rate was adjusted up to a maximum of 100% of left ventricular blood flow initially and thereafter to 30--40% of cardiac output for chronic support. A total of 15 patients with myocardial infarction, myocarditis and failing cardiac condition post-surgically were supported for 9--172 hrs. Six of the 15 survived. Adequate flow control in ventricular bypass support is important and the regimen developed in experimental studies proved effective clinically.

Adolescent↗
PubMed1977

Aortic cannulation for cardiopulmonary bypass.

The surgical technique and complications of aortic cannulation for arterial return in total body perfusion utilizing oxygenator were presented based on our experience of 400 patients. Major complications encountered were laceration and bleeding (1 case), hematoma formation and bleeding (2 cases), and malpositioning of the catheter resulting in mild brain damage (1 case). All underwent re-operation with 4 survivals. Aortic cannulation is simple to perform, easy to maintian stability in cardiopulmonary bypass and with much less risk of retrograde dissection in all ages.

Aorta↗
PubMed1977

Ultrastructural changes of the dog myocardium in extracorporeal circulation.

The effects of the cardiopulmonary bypass circulation on the cardiac muscle cells were studied electron microscopically. Subendocardial hemorrhage was commonly recognized in both ventricles. However, it appeared earlier and more severely in the right ventricle than in the left ventricle. Clear flocculent areas containing numerous filamentous structures were originated from degradation of myofibrils. Degradation of myofibrils occurred within 1 hour after bypass circulation. Degenerative changes of myocardial cells such as zonal lesions, contraction bands and swelling or condensation of mitochondria appeared in both ventricles. Damages of myocardial cells in right ventricular wall were more severer as compared with those in the left throughout the period of observation.

Animals↗
PubMed1977

Spectral analysis of body sway.

The frequency spectrum of the center of gravity in normal subjects while standing was recorded by using a platform-strain gauge system and a digital computer. Individual differences of the spectral patterns resulted in the classification of three types. Averaged divisional frequency of each type was calculated in the range below 1 Hz in which the main change between the values with eyes open and those with eyes closed appeared as the frequency shift.

Adolescent↗
PubMed1977

A technique for the repair of a single or common ventricle.

A new extensive operative technique with several points of important surgical significance was applied to six patients with a single or common ventricle in whom the types of anomalies consisted of common ventricle, Van Praagh's type C, in one instance and single ventricle, Van Praagh's type A and B, in five instances. The important points of this technique are an atrial approach designed to avoid damage to the ventricular function; reconstruction of the ventricular septum using a pouch graft with specially tailored, substitute Dacron vessels; adequate positioning of the prosthetic septum, resulting from use of a pouch graft; special consideration given to suturing at the site of attachment of the interatrial and interventricular septum to lessen damage to the conduction system, and double valve replacement. The adequacy of such extensive surgical repairs cannot be judged accurately until more patients are operated upon.

Child↗
PubMed1977

Pregnancy in patients with a prosthetic heart valve.

Pregnancy and delivery were analyzed in 23 women one to ten years after undergoing prosthetic heart valve replacement. The main points of management during pregnancy and delivery were cardiac management and management against thromboembolism. The functional status of the pregnant patients was grade I of the New York Heart Association criteria in eight, grade II in 13 and grade III and higher in two. There were seven patients during pregnancy and eight after delivery who required hospitalization and treatment for congestive heart failure. Thromboembolism was observed in two during pregnancy and puerperium. Five of the patients were not given anticoagulation therapy, but when thromboembolism developed, warfarin was administered. Warfarin therapy was given indefinitely to seven patients, and 11 were given massive dosages of dipyridamole. In the first two groups, four patients had episodes of thromboembolism.

Adult↗
PubMed1976

Surgical treatment of congenital heart disease with special reference to the application of hypothermia.

This report presents the results of operation for congenital heart disease using two different methods of hypothermia: (1) Immersion hypothermia alone. Of the 782 patients who underwent open-heart operations using this method the results were good in patients whose intracardiac surgical repair took less than one hour (average mortality rate, 5.6%). (2) Rapid extracorporeal cooling. Of the 269 patients with congenital heart diseases such as ventricular septal defect, tetralogy of Fallot, or atrioventricular canal with low cardiac reserve who underwent operation with mild to moderate hypothermia utilizing rapid extracorporeal cooling, the mortality was 11.2%. In the 151 patients with more serious defects, including the extreme form of tetralogy of Fallot, single ventricle, and truncus arteriosus, who underwent open-heart operations with deep hypothermia utilizing extracorporeal cooling, the mortality rate was 15.2%.

Adolescent↗