Biomedical subjects

K To

Publications and source records attributed to K To.

29 records · Page 2Linked to original sources

PubMed1989

Posterior chamber intraocular lens dislocations and malpositions.

Decentration and malposition of posterior chamber intraocular lenses (PC IOL) accounts for one of the remaining and unresolved conditions associated with the implantation of these lenses. This condition assumes importance since in approximately 50% of cases where a PC IOL is removed there is an aspect of improper positioning. The common types of malpositions are: pupil capture; sunset syndrome; sunrise syndrome; horizontal decentration; and the windshield wiper syndrome. This paper will explore the causes and management of these conditions and discuss the virtues of capsular bag implantation.

Eye Diseases↗

PubMed1987

Semiconductor laser endophotocoagulation of the retina.

Laser endophotocoagulation is an important technique in vitreoretinal surgery. We performed successful retinal endophotocoagulation in the eyes of Dutch-belted rabbits, using high-power phased-array semiconductor lasers, emitting at 808 and 817 nm. The laser itself measured 25 X 30 X 21 mm, was air cooled, and was portable. At a treatment power of 100 mW, uniformly white photocoagulation lesions were seen at exposure durations of 0.2 to 1.0 s. Lesions were similar in appearance to argon laser photocoagulation lesions, as determined by ophthalmoscopy and fluorescein angiography. Thin-section histologic examination of acute lesions revealed injury localized to the outer retina; chorioretinal scar formation was noted ten days after photocoagulation. To our knowledge, this study is the first in which therapeutically useful lesions were produced using a diode laser and demonstrates the feasibility of using these highly efficient and compact laser sources for ophthalmic photocoagulation.

Animals↗

PubMed1987

Presence of retinal autoantigen in normal mice: absence in strains with retinal degeneration.

We examined the eyes of four strains of mice to determine if some or all contained an antigen which might cross-react with an antigen of guinea pig retina. To do this, we prepared guinea-pig antibody to guinea-pig retinal extract by immunizing Hartley guinea pigs with guinea-pig retinal extract in two different adjuvants. The retinal tissue of Balb/c and C57B1/6J mice stained well when we used the guinea-pig antibody to guinea-pig retinal extract. In contrast, the eyes of a subline, i.e., C57B1/6J-rd with retinal degeneration, did not stain. Likewise, the eyes of C3H/HeJ and SJL mice with abnormal retinas did not stain. The latter two strains are known to have retinal degeneration. The control studies were negative. This study shows that normal murine eyes have at least one antigen which cross-reacts with a guinea-pig retinal antigen. It also shows abnormal mouse retinas lack this antigen.

Animals↗

PubMed1976