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K Tsachev

Publications and source records attributed to K Tsachev.

32 records · Page 2Linked to original sources
PubMed1988

[Analytical reliability of the results of determining pH, pCO2 and pO2 with the ABL 300 (Radiometer) automatic pH and blood gas analyzer].

The analytical reliability of the determination of pH, pCO2 and pO2 by the automatic analyzer "ABL 300" (Radiometer) was studied. Control materials were used: Confirm, Acidbasol and Qualicheck in the normal, acid and alkaline sphere, and arterial blood, too. The precision within run and between runs for pH and pCO2 meets the contemporary standards (variation coefficient: pH--below 0.2%, pCO2--below 5%. The precision between runs for pO2 is unsatisfactory by low partial oxygen pressure. The accuracy of the three directly determined indices meets the contemporary standards. The comparative analysis of the results obtained by "ABL 300" and "Corning 178" shows a high degree of correlation between the two apparatuses.

Autoanalysis↗
PubMed1988

[Treatment of patients with postmenopausal osteoporosis and steroid-induced osteoporosis with the preparation Rocaltrol (1,25/OH/2 vitamin D3)].

A clinical trial of the drug "Rocaltrol" was carried out on 16 patients with osteoporosis, II of them with menopause osteoporosis and 5 with steroid-induced osteoporosis. The mean age of the patients was 53.1 +/- 11.1 years. The mean daily dose of the drug was 0.46 +/- 0.08 mg/24h. The treatment lasted 6 months. All patients showed improvement of the general condition and of calcium balance. Reliable increase of the total calcium and phosphorus levels and of the 24-hour calcium urine excretion were established, the maximal values being at the end of the third month. The X-ray examination showed stabilization of the bone changes and lack of new compression fractures. It is supposed that the drug improves the intestinal resorption of calcium and phosphorus and suppresses the bone resorption. This is proved by the reliable decrease of serum alkaline phosphatase level after the 6 month treatment. In all patients clinical improvement was established with diminishing of the bone aches and retaining the body height before and after the treatment.

Adrenal Cortex Hormones↗
PubMed1984

[Analytical reliability of the results of a pH and blood gas study using automatic analyzers].

The analytical reliability was studied of the results from the determination of pH, pCO2, and pO2 obtained by automatic analyzers "Corning 178" and "ABL 2". Control materials Confirm, Certain and Acidbasol were used for that purpose, within the normal, acid and alkaline region, as well as arterial blood. The reproducibility in series and in time for all three parameters correspond to the present day requirements for both preparations (VC: pH--under 0,2%; pCO2 and pO2--under 5%), pH--better for "Corning 178". The accuracy of the results for pH and higher values of pO2 is better (d%: pH--under 0,2%; pO2--under 5%). With the diminution of the values of the latter index--the accuracy deteriorated. The accuracy established for pCO2 is unsatisfactory with both the apparatuses and with all three control materials. The results from the comparative analysis reveal a high-degree positive correlation between the apparatuses (rover 0,9). The analytical reliability established for both automatic pH and blood gases analyzers is sufficient to provide the diagnostic reliability of the results necessary for the clinical practice.

Acid-Base Equilibrium↗
PubMed1979

[Our experience with outside laboratory quality control].

The results from the national outside laboratory qualitative control of the clinical diagnostic laboratory investigations for the period September 1975 -- May 1977 were described. The following interlaboratory discrepancy was found on base of a systematic analysis of the data from the last two ring-like check-ups, November 1976 and May 1977, exressed by the variation coefficient (V.C. %); total protein, sodium, potassium and chlorides -- under 10%; cholesterol, urea and total fats -- between 10 and 20%; calcium, phosphorus, iron and creatinine -- over 20%. The highest per cent of admissible results are found with total protein -- to 85%; cholesterol -- to 70.38%; glucosa -- to 73.17%, urea -- to 69.23%, potassium -- to 59.46%, chlorides -- to 57.9%. With sodium, phosphorus, calcium, iron creatinine and uric acid the "admissibility" fluctuates about or under 50 per cent. The values of the qualitative-control indices discussed are comparable with the values obtained from them in the interlaboratory comparisons of other countries.

Bulgaria↗