[Erythrocyte sedimentation rate in intracranial supratentorial].
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Biomedical subjects
Publications and source records attributed to K Turowski.
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The authors report 31 patients treated surgically for chronic bilateral subdural haematomas stressing the diagnostic difficulties in such cases and discussing the value of radiological investigations and surgical methods, especially multipoint trepanation.
Drawings made by 25 patients with neurosurgical diseases causing focal lesions in the posterior areas of the right, not dominant cerebral hemisphere due to expanding changes. Experimental clinical investigations by the method of Luria demonstrated in these cases presence of left-sided visuospatial agnosia. The material was analysed from the point of view of the features of drawings characteristic for the syndrome of disturbances and the localizatory and diagnostic value of drawings. Characteristic disturbances of drawings and their placement were observed suggesting that the patients ignored the left half of the visual space due to damage to the right parieto-occipital non-dominant cerebral hemisphere. The drawing test is regarded as a valuable method for the diagnosis and localization of lesions in the neurological and neuropsychological practice.
The distribution of ABO blood groups was analysed statistically in 271 patients treated for glioblastoma multiforme. The control group included 500 patients treated for craniocerebral trauma. A statistically significant difference was observed in the distribution of ABO blood groups between these patient groups, with higher frequency of group A and lower of group O in the patients with glioblastoma multiforme.
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In 25 patients with hydrocephalus of various grades and aetiology treated by insertion of ventriculoatrial valves neuropsychological investigations were carried out before and after this operation using the method of Luria and certain psychometric tests. The obtained results made possible isolation of three grades of impairment of higher nervous functions: III--afunction--10 patients, II--dysfunction--12 patients, I--eufunction--3 patients. Control neuropsychological examination two weeks after the operation demonstrated improvement of higher nervous functions in 6 cases with grade III and 11 patients with grade II impairment. In these cases radiological investigations demonstrated evidence of normotensive and hypertensive hydrocephalus and this was confirmed by measurements of intraventricular pressure of the cerebrospinal fluid. In 5 cases with grades III and II of damage no improvement was found. Radiograms and measurements of intraventricular pressure suggested in these cases hydrocephalus due to brain atrophy.
The authors report an analysis of the results of neuropsychological investigations of patients treated for supratentorial gliomas. A syndrome of the most frequently observed disturbances of higher nervous activity has been outlined. The diagnostic, localizatlry and differential diagnostic value of neuropsychological investigations has been assessed and found to a useful auxiliary clinical method.
The authors determined the level of neuraminic acid in the serum of 50 patients with encephalomalacia and 25 patients with cerebral haemorrhages on the 1st, 3d and 7th days of the disease. Twenty healthy subjects served as controls. A statistically significant rise in the concentration of this substance was observed in both groups of patients throughout the whole period of observations.
As a contribution to the present discussion on genetic determination of gliomas two cases of gliomas in father and son are reported. Familial occurrence of gliomas suggests a possible role of genetic factors in the development of intracranial gliomas.
The results of combined treatment were analysed in 38 cases of cerebral gliomas. In the group of 14 patients with glioblastoma multiforme treated surgically and by later radiotherapy and chemotherapy by the schedule of Hildebrand a mean arrival time of 116 weeks was obtained and the one-year survival rate was 71%. In the group of inoperable gliomas (16 cases) treated by radiotherapy and chemotherapy the mean survival time was 47 weeks and the one-year survival rate was 44%.
The authors discuss the results of surgical treatment of traumatic intracerebral haematomas on the basis of own material of 44 cases and a survey of literature. The rarity of this complication of injuries and the diagnostic difficulties are stressed, the usefulness of surgical approach is analysed and the prognostic importance of such factors as the clinical course of haematoma, severity of the patient's condition, and coexistence of other intracranial injuries is discussed.
The authors discuss the results of surgical treatment of intracranial epidural haematomas in the light of own material of 84 cases. In relation to reports in the literature the authors call attention to diagnostic difficulties in atypical cases and discuss the importance of signs of prognostic value for the life of the patient and factors increasing mortality. The signs of poor prognosis include: respiratory disturbances, bilateral pupillary dilatation, coma with disturbances of basic vital functions and decerebrate rigidity. The mortality is increased by co-existent intracranial injuries, especially brain lacerations. The prognosis was best in cases operated upon during the lucid interval. Very good and good results of treatment were achieved in 86% of cases, satisfactory in 8%, with a general mortality of 26%, which was highest in the group with acute haematomas reaching 43%.
A case of giant osteoma of the external lamina of the cranial bone is reported. The report is published as a contribution to the discussion on the methods of surgical removal of these tumours. The authors confirm the validity of the view that osteomas should be removed radically from the external lamina leaving the internal lamina intact if it is free of osteoma.
Since the introduction of CT it has become possible to trace the pattern of brain changes after removal of subdural haematoma. Postoperative studies show frequently presence of haematoma residues, and this is connected with the problem of deciding about establishing of indications to reoperation, especially difficult if the patient is in a good clinical condition. The clinical status was compared with CT findings preoperatively and postoperatively in 20 patients subjected to operations for chronic subdural haematomas. A statistically significant correlation was found between the size of the mass effect in CT before and after the operation and the severity of the clinical condition. Major mass effect with high-grade ventricular shifting is more frequently connected with partially haemolysed haematoma in CT. The thickness of subdural haematoma exceeding 20 mm correlated with severe clinical condition, and increased the probability of hemiparesis persistence after the operation. Finding of residual haematoma in CT imaging after the operation, especially when not associated with high-grade mass effect, and with good clinical condition should not be accepted as an indication to repeated operation. In the presented material out of 15 patients with good clinical condition 12 had CT evidence of residual haematoma, and only one had reoperation in view of persisting evident mass effect.
Since the introduction of computerized tomography (CT) it has been possible to trace the image of the brain after removal of subdural haematoma. Postoperative studies demonstrated often presence of residual haematoma. This raises the problem of establishing indication to reoperation, especially of patients with good clinical condition. The clinical condition and CT images before and after operation were assessed in 20 patients treated surgically for chronic subdural haematoma. A statistically significant correlation was found between the magnitude of the effect of the space occupying lesion in CT image and the severity of the clinical condition. A high-grade mass effect with major ventricular system shifting was more often connected with presence of partly haemolysed haematoma in CT. Subdural haematoma thickness exceeding 20 mm correlated with serious clinical condition of the patient, and increased the likelihood of hemiparesis persisting after the operation. Finding of residual haematoma in postoperative CT should not be an indication to reoperation, if not associated with high-grade mass effect and if the clinical condition is good. In our material out of 15 patients with good clinical condition postoperatively residual haematoma was detected by CT in 12 cases, but only one had to be reoperated because of persistent high-grade mass effect.