Biomedical subjects
Publications and source records attributed to K W Burchard.
PASG is commonly employed for the prehospital therapy of traumatic hypovolemic hypotension. Although complications are reportly uncommon, several reports of compartment syndromes after PASG application and the present report of a crush syndrome following PASG application raise serious questions about the currently accepted guidelines for PASG therapy.
Records of 65 surgical patients with positive fungal blood cultures were reviewed to address risk, overall mortality, and treatment. Negative urine cultures did not rule out sepsis. Staphylococcus epidermidis sepsis was present in 27 (42%) of the patients. In 70% of whom it occurred before or during fungemia. Increased mortality correlated with the use of multiple antibiotics, antibiotic use for prolonged periods, and with associated bacterial sepsis. Stopping antibiotic therapy did not reduce mortality. Amphotericin B reduced mortality in patients with dissemination, indicating that it is the treatment of choice for disseminated fungemia and that antibiotic therapy should not be discontinued when concomitant bacterial sepsis is present.