PubMed Health⌕ Search

Biomedical subjects

K Watts

Publications and source records attributed to K Watts.

16 recordsLinked to original sources
PubMed2004

Injury prevention training: a cluster randomised controlled trial assessing its effect on the knowledge, attitudes, and practices of midwives and health visitors.

OBJECTIVE: To evaluate the effectiveness of injury prevention training. DESIGN: Cluster randomised controlled trial. SETTING: Primary care facilities in the East Midlands area of the United Kingdom. SUBJECTS: Midwives and health visitors. INTERVENTION: Evidence based training session on the risks associated with baby walkers. MAIN OUTCOME MEASURES: The primary outcome measures were knowledge of baby walker use and walker related injury, attitudes towards walkers and towards walker education, and practices relating to walker health education. RESULTS: Trained midwives and health visitors had greater knowledge of the risks associated with baby walkers than untrained midwives and health visitors (difference between the means 0.22; 95% confidence interval (CI) 0.12 to 0.33). Trained health visitors had more negative attitudes to baby walkers (difference between the means 0.35; 95% CI 0.10 to 0.59) and more positive attitudes towards baby walker health education (difference between the means 0.31; 95% CI 0.00 to 0.62) than untrained health visitors. Midwives who had been trained were more likely to discuss baby walkers in the antenatal period than those who were not trained (odds ratio 9.92; 95% CI 2.02 to 48.83). CONCLUSIONS: Injury prevention training was associated with increased knowledge, more negative attitudes towards walkers, and more positive attitudes towards walker education. Trained midwives were more likely to give advice antenatally. Training did not impact on other practices. Larger trials are required to assess the impact of training on parental safety behaviours, the adoption of safety practices, and injury reduction.

Attitude of Health Personnel↗
PubMed2001

A comparison of the shuttle and 6 minute walking tests with measured peak oxygen consumption in patients with heart failure.

This study investigated the use of an incremental, externally-paced 10 m shuttle walk test (SWT) as an objective, reliable and predictive test of functional capacity in patients with heart failure (CHF). The SWT was compared to a 6 minute walk test (6WT) and a maximal symptom-limited treadmill peak oxygen consumption (VO2peak) test. Experiment 1 examined the reproducibility of the SWT. Two SWF trials were performed and distance ambulated (DA), heart rate (HR) and rate of perceived exertion (RPE) results compared. In experiment 2, SWT, 6WT, and VO2 peak tests were performed and HR. RPE and ambulatory VO2 compared. The SWT demonstrated strong test/retest reliability for DA (r = 0.98). HR (r = 0.96) and RPE (r = 0.89). Treadmill VO2 peak was significantly correlated with DA during the SWT (r = 0.83, P < 0.05), but not the 6WT. SWT peak VO2 (18.5 +/- 1.8 ml.kg(-1) x min(-1)) and treadmill VO2 peak (18.3 +/-2.0 ml.kg(-1) x min(-1)) were also highly correlated (r = 0.78, P < 0.05). Conversely, 6WT peak VO2 and treadmill VO2 peak were not significantly correlated. This study suggests the SWT is a reliable, objective test, highly predictive of VO2 peak which may be a more optimal field exercise test than the self paced 6WT.

Exercise Test↗
PubMed2001

Contracting for smoking and pregnancy interventions: current practice across England.

In order to understand the commissioning of smoking and pregnancy interventions across England prior to the implementation of the Government's national strategy, "Smoking Kills: A White Paper on Tobacco" in 1998, a postal survey was undertaken amongst all 96 Health Authorities (purchasers) and 207 Maternity Service Provider Units (providers) in England. The main outcome measures included the type and duration of contract agreements/service specifications, the level and nature of smoking and pregnancy interventions, barriers to commissioning smoking and pregnancy interventions, data collection and monitoring of activity and quality. A quarter of health authorities were encouraging smoking cessation through contract agreements. The level and complexity of contract agreements and service specifications varied tremendously. Existing smoking and pregnancy interventions were diverse and ad hoc. Data collection and monitoring were haphazard and inconsistent making cross-country comparisons difficult. The commissioning of smoking and pregnancy interventions across England during 1997 and 1998 appeared to be inadequately prioritised. These findings offer a benchmark for observing changes in practice following the recent change of government policy.

Contract Services↗
PubMed2000

Dissociation between Fas expression and induction of apoptosis in human islets of Langerhans.

There is increasing evidence that inappropriate induction of apoptosis in pancreatic beta-cells may precede the development of type 1 diabetes in animal models and in man. One mechanism by which this has been proposed to occur involves up-regulation of the death receptor Fas on beta-cells, resulting in apoptosis of the Fas-bearing beta-cells upon ligation of the receptor. We have examined this hypothesis in isolated human islets of Langerhans and show that--in contrast to data obtained with rodent beta-cells--expression of Fas per se is not sufficient to allow induction of apoptosis upon addition of agonistic anti-Fas serum.

Animals↗
PubMed1999

Choosing an intravenous securement system.

A variety of intravenous securement devices now offer alternatives to the use of gauze and tape. Home health nurses must recognize these devices and be able to choose among the available options in making product recommendations to support enhanced patient outcomes specific to infusion therapy.

Bandages↗
PubMed1998

ORBIS--training nurses worldwide in ophthalmic care.

The unique nature of the ORBIS teaching mission is reflected in many arenas. The ORBIS organization recognizes that the nurse's role is critical to achieving their mission of preventing blindness through education, hence the emphasis on nurse education. The roles of the head nurse, nurse educator, staff nurses, and the biomedical engineering department are discussed briefly with emphasis on the needs assessment and the different programs offered to meet the identified needs.

Aircraft↗
PubMed1998

Cloning, expression, sequence determination, and chromosome localization of the mouse complement C3a anaphylatoxin receptor gene.

The complement C3a anaphylatoxin receptor (C3aR) is a seven-transmembrane G-protein coupled chemoattractant receptor that on binding the C3a peptide ligand mediates numerous cellular responses, including histamine release from mast cells. smooth muscle contraction, and the directed migration of eosinophils. To delineate the murine C3aR coding sequence, gene structure, 5'-flanking region, and chromosome location, cDNA and genomic clones encoding the mouse C3a receptor were isolated, characterized, and used in fluorescence in situ hybridization experiments. The results from this study indicate that the murine C3a receptor structural gene is a single copy gene of approximately 8 kb comprised of 2 exons which are separated by a large intervening intron of 4724 bp. The first exon encodes 97 bp of 5'-untranslated sequence. Exon 2 encodes the remaining 8 bp of 5'-untranslated sequence and the entire coding and 3'-untranslated sequences. This genomic organization is typical of most other chemoattractant receptor genes in that the entire coding sequence is contained on a single exon. The human and mouse C3a receptor genes were localized to syntenic chromosomal bands 12q13.2-3 and 6F1, respectively. No other seven-transmembrane receptor genes, to date, have been localized to these chromosomal regions. Primer extension experiments using mouse macrophage RNA indicated a single transcriptional initiation site. Sequence analysis 5' of the transcriptional site indicated a TATA-less promoter with possible cis-acting motifs that may regulate C3a receptor gene expression. These included the recognition sequence for the nuclear transcription factor SP1 and the phorbol ester response sequence which binds the Fos/Jun heteromeric transcription factor AP1.

Amino Acid Sequence↗
PubMed1992

Peritoneal dialysis training in a patient with multiple congenital anomalies.

We report an adult patient with multiple congenital anomalies including absent right arm, short stature, and scoliosis who has been trained and successfully performs continuous cycling peritoneal dialysis independently. Motivated patients with end stage renal disease and various anomalies should be considered for peritoneal dialysis training.

Abnormalities, Multiple↗
PubMed1991

Use of the peritoneal equilibration test in pediatric dialysis patients.

The peritoneal equilibration test (PET) has been used in adult peritoneal dialysis (PD) patients to determine PD efficiency and optimal dialysis prescription. To investigate its usefulness in pediatric PD patients, we performed the PET in 10 patients divided into 2 groups: 3 patients less than 2 years of age (group 1) and 7 patients aged 5 to 17 years (group 2). The PET was performed after an overnight dwell by standard protocol with an overnight dialysate sample and 6 dialysate samples during the 4 hour test. Dialysate to plasma (D/P) ratios were calculated for creatinine (Cr), urea, and protein. D/PCr over time was similar in both pediatric groups compared to adults. D/P urea over time was lower in both pediatric groups compared to published adult data. D/P protein over time was markedly increased in both pediatric groups and was highest in the smallest patients. D/P ratios are different in pediatric PD patients compared to adults. In order to be used to assess dialysis efficiency, normal values for the PET test in children need to be established.

Adolescent↗
PubMed1988

Interval-coded texture features for artifact rejection in automated cervical cytology.

In order to improve the separation between abnormal cells and noncellular artifacts in the CERVIFIP automated cervical cytology prescreening system, 22 different object texture features were investigated. The features were all statistical parameters of the pixel density histograms or one-dimensional filtered values of central and border regions of the object images. The features were calculated for 231 images (100 cells and 131 artifacts) detected as Suspect Cells by the current CERVIFIP and were then tested in hierarchical and linear discriminant classifiers. After selecting the two best features for use in a hierarchical classifier, 83% correct classification was achieved. One of these features was specifically designed to remove poorly focused objects. With maximum likelihood discrimination using all 22 features, an overall correct classification rate of 90% was obtained.

Cell Division↗
PubMed1986

Subjective memory assessment and test performance in elderly adults.

The everyday memory of a group of elderly adults was assessed using techniques developed for use with younger head-injured people (Sunderland et al., 1983). The participants completed a memory questionnaire and a daily checklist; their spouses gave their assessment using a separate questionnaire. These subjective methods showed only moderate agreement, and the questionnaire had low test-retest reliability. It appears that these methods of subjective memory assessment have little validity when used with normal elderly adults. Two positive findings did emerge: As in previous studies, a story recall test was the strongest predictor of reported memory performance; and despite a universal belief among elderly adults that their memory had deteriorated with age, very few of them felt that they were at all handicapped by forgetfulness in everyday life.

Aged↗
PubMedDate not supplied

A comparison of ambulatory oxygen consumption during circuit training and aerobic exercise in patients with chronic heart failure.

PURPOSE: This study compared the exercise intensity of a combined aerobic and resistance exercise circuit training session with the exercise intensity of continuous aerobic exercise in patients with chronic heart failure (CHF). METHODS: Peak oxygen consumption (VO2peak) and muscular strength (1 repetition maximum) were assessed in six CHF patients (age 62 +/- 3 years). Heart rate, rate of perceived exertion (RPE), blood pressures, ambulatory oxygen consumption (VO2), and ventilatory data were measured during two types of exercise: continuous cycling on a bicycle ergometer (aerobic [AER] session) and combined AER and resistance exercise (circuit training [CIR] session). RESULTS: There were no significant differences in VO2, RPE, heart rate, or hemodynamic responses (rate pressure product, diastolic blood pressure, or mean arterial pressure) during exercise, between the two sessions. Systolic blood pressure was significantly lower during CIR (P < 0.05). Minute ventilation and tidal volume were significantly higher (P < 0.0001 and P < 0.01, respectively) and respiratory frequency significantly lower (P < 0.005) during CIR. During CIR, RPE significantly correlated with VO2 (P < 0.01), whereas heart rate did not. Conversely, during the AER session HR correlated with VO2 (P < 0.01), but RPE did not. CONCLUSIONS: Circuit training is a well-tolerated form of exercise training for CHF patients that is associated with similar oxygen and hemodynamic demand to aerobic exercise. Results suggest that RPE may be a better method of prescribing and monitoring exercise intensity during CIR, with heart rate the preferred measure of intensity during aerobic exercise.

Aged↗
PubMedDate not supplied

Evaluation of the BAX system for detection of Listeria monocytogenes in foods: collaborative study.

A multilaboratory study was conducted to compare the automated BAX system and the standard cultural methods for detection of Listeria monocytogenes in foods. Six food types (frankfurters, soft cheese, smoked salmon, raw, ground beef, fresh radishes, and frozen peas) were analyzed by each method. For each food type, 3 inoculation levels were tested: high (average of 2 CFU/g), low (average of 0.2 CFU/g) and uninoculated controls. A total of 25 laboratories representing government and industry participated. Of the 2335 samples analyzed, 1109 were positive by the BAX system and 1115 were positive by the standard method. A Chi square analysis of each of the 6 food types, at the 3 inoculation levels tested, was performed. For all foods, except radishes, the BAX system performed as well as or better than the standard reference methods based on the Chi square results.

Chi-Square Distribution↗