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Biomedical subjects

K Yabata

Publications and source records attributed to K Yabata.

7 recordsLinked to original sources

Two Japanese cases of battered child syndrome with retinal hemorrhage.

We present 2 cases of battered child syndrome with retinal hemorrhage. Case 1 is a 6-year-old boy who was blinded in both eyes following abuse by his mother's common-law husband. Retinal hemorrhages and optic atrophy were found in both eyes. Case 2 is a 6-month-old boy who developed dyspnea following episodes of abuse by his mother's common-law husband. Retinal hemorrhages were visible in both fundi. We believe that retinal hemorrhage is the most frequent clinical finding in abused children and its presence should alert the ophthalmologist to suspect battered child syndrome.

Battered Child Syndrome↗

Papilloedema in late-onset citrullinaemia: report of second case.

A young adult patient suddenly began to have episodes of unconsciousness that each lasted for several hours. Brief episodes of lethargy occurred monthly. Biochemical tests disclosed high levels of ammonia and citrulline in the serum. Brain oedema was suggested by CT scan, and optic disc swelling was observed ophthalmoscopically, indicating papilloedema. He died in coma. Deficient activity of argininosuccinate synthetase in the liver was demonstrated. Papilloedema was confirmed histologically. We believe that papilloedema is a serious sign indicating poor prognosis in late-onset citrullinaemia.

Adult↗

Acute retinal necrosis.

We treated 2 patients with unilateral acute retinal necrosis in association with uveitis. The disorder began as anterior uveitis, secondary glaucoma, and retinal vasculitis, and then developed into retinal necrosis within a few months. The aetiology was obscure and the appropriate treatment debatable. We also review reports of patients showing the same clinical characteristics, termed Kirisawa-type uveitis and bilateral acute retinal necrosis, and believe the disorders to be identical.

Acute Disease↗

Atypical gyrate atrophy of the choroid and retina associated with iminoglycinuria.

A 44-year-old woman had a fundus appearance similar to that of gyrate atrophy, a macular lesion, and excessive urinary excretion of proline, hydroxyproline, and glycine. The patient also had abnormal ciliary processes and patchy atrophy of the irides. To our knowledge, this is the first reported case of ocular manifestations associated with iminoglycinuria.

Adult↗

Atypical gyrate atrophy of the choroid and retina and iminoglycinuria.

A 44-year-old woman with atypical gyrate atrophy and iminoglycinuria was described. The serum ornithine level and ornithine-ketoacid transaminase (OKT) activity were both normal. Urinary excretion of proline, hydroxyproline and glycine was markedly increased. This finding, together with the existence of gyrate atrophy with hyperornithinemia due to OKT deficiency, suggests that proline deficiency in the chorioretinal tissues may concern the development of gyrate atrophy.

Adult↗