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Biomedical subjects

K Ying

Publications and source records attributed to K Ying.

26 records · Page 2Linked to original sources

[Development and clinical application of dental spot weld & heat-treat tri-uses device].

A spot weld & heating treatment tri-uses device based on modern mechanical-electric technique, was developed for dental spot weld, stainless steel orthodontic wire heating-reversion and Ni-Ti orthodontic wire heating-overload metamorphism. The device will be very helpful instrument in orthodontic clinic. The paper not only described the operating methods of the device, but also discussed the Performance-improved principles of stainless steel orthodontic wire and the principles of heating overload metamorphism of Ni-Ti orthodontic wire.

Dental Soldering↗

[Detection of telomerase activity in bronchoscopic brush-off cells in lung cancer patients].

OBJECTIVE: To investigate the diagnostic significance of the detection of telomerase activity in the exfoliated cells obtained from fiberobronchoscopic brushing. METHODS: The techniques of TRAP-PCR-ELISA and TRAP-silver staining were employed to detecte telomerase activity in 57 cases with pulmonary diseases. RESULTS: Telomerase activity in the lesion side of lung cancer patients (N = 23) was significantly higher than that in the contralateral side of the same patient (P < 0.05), and in patients with pneumonia (P < 0.05). Positive rate of telomerase activity detection in lung cancer patients (91.3%) was significantely higher than that of cytological examination (52.3%, P < 0.05). In 83.3% of the cases examined, exfoliated cells showing cytological dysplasia were found to be telomerase activity positive. CONCLUSION: Detection of telomerase activity in the exfoliated cells obtained from fiberobronchoscopic brushing may be an effective and sensitive method in the diagnosis of pulmonary malignant diseases.

Adenocarcinoma↗

Echo-time reduction for submillimeter resolution imaging with a 3D phase encode time reduced acquisition method.

To achieve optimal image quality and highest spatial resolution for inner ear imaging with a 3D gradient echo sequence, it is necessary to minimize susceptibility dephasing effects by using very short TE. Fractional RF pulses and echoes can yield short TE for moderate spatial resolution; however, for voxel size of less than 1 mm, TE is limited by the phase encode gradients. We present a method to obtain very short effective TE by using short triangular shaped phase encode gradients to sample the central portions of k-space and progressively longer trapezoidal gradients for the outer portions of k-space. A 3D pulse sequence employing the modified phase encoding scheme for both in-plane and slice phase encoding directions was implemented and tested on phantoms and in vivo. The effective TE equals the minimal TE used for the central k-space portions. Submillimeter resolution (0.35 x 0.35 x 0.7 mm3) images of the inner ear were obtained with effective TE of 3.2 ms and were compared with standard 3D images with TE of 8 ms. With this pronounced TE reduction, the susceptibility artifacts at air/fluid interfaces are significantly reduced.

Adult↗

Cardiovascular responses to external counterpulsation: a computer simulation.

A mathematical model of the human cardiovascular system is presented which includes a simulation of cardiac assistance by external counterpulsation. The model was established to study the effects of external counterpulsation on cardiovascular haemodynamics. The closed simulation includes both the left and the right heart and the pulmonary circulation. The model is able to provide data for the behaviour of the system under varying modes of assistance. Our results suggest that control of external counterpulsation is more difficult than control of the intra-aortic balloon pump and requires regulation of a larger number of variables. The results also suggest that a tradeoff exists between improved oxygen delivery to the heart and reduction in the oxygen consumption of the myocardium, an observation similar to that reported for the intra-aortic balloon pump.

Counterpulsation↗

Optimization of submillimeter-resolution MR imaging methods for the inner ear.

Submillimeter-resolution magnetic resonance (MR) imaging of the inner ear is valuable for diagnosis and treatment planning. Its main advantage for investigations of underlying disease is that it can directly depict the fluid spaces of the membranous labyrinth rather than define only the bony canal, as does computed tomography. A systematic evaluation of factors influencing high-resolution three-dimensional (3D) gradient-echo imaging of the inner ear with a standard clinical MR system is presented. This includes the evaluation of various radio-frequency coils, the design of steady-state pulse sequences, and the optimization of acquisition parameters. A quantitative analysis was facilitated by computer simulations and image processing. The highest signal-to-noise ratio for the membranous labyrinth was obtained with a single 3-inch (7.6-cm) receiver coil and a 3D GRASS (gradient-recalled acquisition in the steady state) sequence with the minimal achievable TR msec/TE msec of 25/7 and a 40 degrees--60 degrees flip angle, which yielded acceptable images with minimal voxel volumes of 0.1 mm3 in 14 minutes.

Ear, Inner↗

Adaptive filtering for high resolution magnetic resonance images.

We present a study of least mean square (LMS) based adaptive filters for high resolution magnetic resonance (MR) images to improve signal-to-noise ratio (SNR) while maintaining sharp edges. Five variations of a new technique that senses the type of noise or the presence of an edge in the filtering window, called adaptive filtering with noise estimation (AFEN) are presented and compared with the basic two-dimensional LMS (TDLMS) algorithm, adaptive filtering with a mean estimator (AFLME), a two-dimensional averaged LMS (TDALMS) algorithm, and a two-dimensional median weighted LMS (TDMLMS) algorithm. Although TDLMS, TDALMS, and TDMLMS filters give better SNR improvement when applied uniformly to an image, they significantly blur edges. The AFLME and AFEN filters both show approximately a factor of 2 SNR improvement with much better retention of edges, with AFEN showing slightly better performance for both SNR and edge sharpness in phantom and in vivo inner ear images.

Algorithms↗