The use of LAL as an alternative to the CFR rabbit pyrogen test for disodium ticarcillin.
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Animals↗
Biomedical subjects
K Z McCullough
Publications and source records attributed to K Z McCullough.
Effect of semisynthetic penicillins on the Limulus lysate test.
Semisynthetic penicillins in concentrations greater than 1.0% (wt/vol) were found to inhibit the limulus lysate assay for endotoxin.
Arachnida↗
Variability in the LAL test: comparison of three kinetic methods for the testing of pharmaceutical products.
Data presented in this study indicate that there is considerable variability in spike recoveries between three different kinetic LAL methods as used for the testing of a variety of parenteral products. However, successful spike recoveries were observed for each of the thirteen products under test on at least one of the three kinetic methods used, suggesting that problems caused by spike recovery variability may be easily controlled in the laboratory by flexibility in the choice of method.
Limulus Test↗