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Biomedical subjects

K Zámolyi

Publications and source records attributed to K Zámolyi.

8 recordsLinked to original sources

[Emergency situations in hypertension].

Hypertensive emergency is an acute, perilous state connected with a marked increase of peripheral vascular resistance and the decrease of tissue perfusion. Its development depends on the rate of blood pressure elevation, on the severity of developed hypertension and the state of the vascular system. Although hypertensive emergencies can be grouped also on symptomatological and etiological basis, regarding the therapeutic measures to be taken, they appear in two well distinguishable forms. In case of hypertensive crisis treatment has to be started without delay, possibly in a few minutes, in states involving the risk of hypertensive crisis treatment has to be initiated within a few hours to avoid extensive damage of the vital organs or fatal outcome. The acute, but controlled reduction of blood pressure must not surpass 15-25% of the medium value. In hypertensive crisis, if possible, parenteral medication--as first aid--urapidil, verapamil, in states with endangering hypertensive crisis sublingual nifedipine, captopril, nitroglycerin may be applied, however in the different emergency states therapeutic intervention has to be individually determined.

Administration, Sublingual↗

The treatment of septicemia in pacemaker patients.

The authors analyzed the data of seven patients who had undergone open heart surgery because of pacemaker endocarditis in the past 4 years. Repeated surgical interventions on the pacemaker system were found to be the most common predisposing factors. Staphylococcus aureus and Staphylococcus epidermidis were the most common causative organisms. Two-dimensional echocardiography was important in the diagnosis of cases with atypical clinical picture and negative blood cultures. We concluded that: (1) any pacemaker patient with fever should be considered to have a pacemaker endocarditis; (2) all of these patients should be examined by two-dimensional echocardiography; and (3) the total removal of the infected hardware seems to be the only way to achieve complete recovery.

Adult↗

[Amiodarone-induced hyperthyroidism causing progression of arrhythmia].

A case of a 38-year-old male with supraventricular paroxysmal tachycardia existing for more than a decade is reported. He has received amiodarone in a daily dose of 800 mg for three years and the tachycardia returned in 1992. New antiarrhythmic drugs were added but no beneficial effect has been achieved and moreover, a case of ventricular fibrillation occurred. The 12-lead ECG performed during tachycardia and the electrophysiological study showed orthodromic AV reentry tachycardia. Laboratory tests performed proved hyperthyreotic state. Attacks of paroxysmal tachycardia were returned and aggravated by the hyperthyreosis induced by amiodarone. Finally, antiarrhythmic drugs were discontinued and methimazol was introduced. Gradually, the patient become asymptomatic within two months. The most important conclusion of the case reported, that the amiodarone induced hyperthyreosis can be subclinical or obscure. Consequently, a regular control of serum thyreoid hormone levels at least twice a year on patients with long term amiodarone administration should be advised.

Adult↗

[The role of two-dimensional echocardiography in the detection of pacemaker-induced endocarditis].

UNLABELLED: The authors analysed the data of eight patients who had to undergo open heart surgery because of pacemaker endocarditis in the last four years. Repeated surgical interventions on the pacemaker system was the most predisposing factor. The most common causative organisms were Staphylococcus aureus and Staphylococcus epidermidis. Two-dimensional echocardiography (2DE) had a decision making role in the diagnosis beside the clinical picture and blood culture. CONCLUSIONS: 1. Each pacemaker patient with fever must be considered to have a pacemaker endocarditis; 2. All these patients must be examined by two-dimensional echocardiography.

Adult↗