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Biomedical subjects

K Zajusz

Publications and source records attributed to K Zajusz.

At least 19 recordsLinked to original sources
PubMed1985

[Effect of directed infrared radiation on the skin and eye of rabbits after acute and chronic exposure].

The establish a threshold dose, an acute experiment was carried out by 30 min. radiation of the rabbit's shaved head with all ranges of infrared, 200 W/m2, 350 W/m2 and 500 W/m2 intensities. Irradiation was prolonged up to 2 hrs. Having established the threshold dose, a chronic (5 months') experiment was carried out, irradiating 9 rabbits' skin (in 3 groups) with 350 W/m2 intensity in the range of all three bands. Similarly, tests on the eye transparent part were performed, irradiating only one eye, the other being handled as the control. The results show that the 350 W/m2 intensity of IR-A and IR-C radiation induces a slight erythema on rabbits' skin under long-lasting radiation, and under all radiation ranges no changes in the eye transparent part result at the 350 W/m2 intensity for the IR-A band and 200 W/m2 for the IR-C band. On the other hand, when irradiating the eye with the IR-B band at the 350 W/m2 intensity, slight infiltrations and defects of the eyeball cornea were found. Temporarily, the 350 W/m2 value for human skin was suggested as the TLV for the directional radiation intensity within IR-A and IR-B. On the other hand, for the eye transparent part the following TLVs have been suggested: for the IR-A band--250 W/m2, for the IR-B--150 W/m2, for the IR-C band--150 W/m2. Those values do not refer to laser radiation and do not guarantee the development of cataract under many-years' exposure.

Animals↗
PubMed1979

[Effect of metal dust on the respiratory system. I. Experimental studies].

The Wistar rats were intratracheally administered 50 mg of PbO dust, the same amounts of metalliferous dust from one of lead--and zinc works and of ferrotungsten dust, and 10--15 mg of cadmium dust (greater doses of cadmium dust resulted in animals' death). After 6 months, and in the case of cadmium dust after 9--12 months, the animals were dissected and their lungs were morphologically examined and hydroxyproline level was determined. In all groups hydroxyproline was found to be increased but fibrosis was different, especially in the group exposed to cadmium dust.

Animals↗
PubMed1979

[Effect of metal dust on the respiratory system. II. Clinical examinations].

Studies were carried out in 4 groups of workers occupationally exposed to cadmium, tungsten, manganese and lead. All those groups were homogeneous, composed exclusively of men aged 35--45, of similar height, body weight, and duration of employment above 10 years. Following the same criteria, a group of forestry workers, unexposed to dust, was randomly selected. The smoking habit was similar in all groups. Several--days--clinical observation included a detailed interview (MRC questionnaire), physical and radiological examination and a wide range of functional tests of lungs. The results reveal clinical and physiopathological symptoms which might be indicative of emphysema. The results of some studies also indicate the possibility of intraparenchymatous fibrosis of lungs in the tungsten--exposed--workers. No clear effects upon the respiratory system were found.

Adult↗
PubMed1979

[Effects of detergents on lead absorption].

The effects of orally administeredated detergents (rokafenol and siarczanol) on the absorption of lead from rabbits alimentary duct were reviewed. The absorption of lead was evaluated by the activity of delta--aminolevulinic acid dehydratase of erythrocytes, delta--aminolevulinic acid level in urine and the level of lead in the blood and liver. The detergents were found to increase the absorption of lead.

Animals↗