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Biomedical subjects

K Zaman

Publications and source records attributed to K Zaman.

At least 73 records · Page 4Linked to original sources
PubMed1990

The effect of aluminium on the heam biosynthesis (in vitro) in bone marrow cells in rats.

The study has been carried out on male Wistar rats. The aim of the present study was to trace the effect of aluminium chloride and aluminium nitrate at concentration 10 microM and 20 microM on haem biosynthesis in vitro in bone marrow cell culture. The ability of haem biosynthesis in bone marrow cell culture after 48 h of experiments with aluminium chloride and aluminium nitrate significantly decreased in relation with the control value.

Aluminum↗
PubMed1990

The effect of aluminium upon the activity of selected bone marrow enzymes in rats.

This study was carried out on male Wistar rats. The bone marrow activities of acetylcholinesterase (AchE-EC.3.1.1.7.), glutathione reductase (GR-EC.1.6.4.2.) and glucose-6-phosphate dehydrogenase (G6PD-EC.1.1.1.49.) were determined as affected by aluminium. The present experiments have revealed that within the first days there will be an increase in enzyme activity in the bone marrow. Simultaneously a decline in the activity of bone marrow could be observed which occurred later in the first course of the experiment.

Acetylcholinesterase↗
PubMed1990

Effects of aluminum on erythroidal cells in bone marrow in rats.

The study has been carried out on Wistar rats. The aim of the present study was to trace the effect of aluminum on erythroidal cells in bone marrow in rats. The number of proerythroblast after 10 days of experiment with aluminum slowly decreased up to 80 days of experiments. However, the number of basophilic erythroblasts after 10 days insignificantly increased but after 20 days gradually decreased up to 80 days of experiments. The bone marrow polichromatic erythroblasts after 10 days of experiment slightly decreased, however after 20, 40 and 80 days of experiments the values decreased significantly. The quality of orthochromatic erythroblasts after 10 days of experiments dropped and after 20, 40 and 80 days of experiments significantly decreased compared to the control value. Aluminum also brings about histological changes in the bone marrow. The statistical significant reductions of hemoglobin and hematocrit levels were found in the aluminum exposed rats.

Aluminum↗
PubMed1989

Purification and partial characterization of a cobalamin-binding protein from chicken egg yolk.

Cobalamin-binding protein has been purified from chicken egg yolk by using DEAE-cellulose with a NaCl gradient. The resultant protein fraction was subjected to bioaffinity chromatography. The Mr was 38,000 by SDS-PAGE and 39,000 by gel filtration, and indicated that it was a glycoprotein. The Stokes radius was 4.3 nm and the pI 4.1. The protein bound 57CO.B12 with a molar ratio of 1:1 and a Kd of 0.41 microM. The CBP composed 296 amino acids residues. The protein-ligand interaction was inhibited by Cbl analogues.

Amino Acids↗
PubMed1989

Medicinal plants with hypoglycemic activity.

This review summarises the literature on the antidiabetic activity of 343 medicinal plants reputed in the indigenous system of medicine or in which the pharmacological activity has been scientifically demonstrated. The data are presented in tabular form. The table reflects the plant parts involved, the nature of the extracts used and the names of the active principles with their structures where known. The pharmacological activities of some of the extracts or of the active principles isolated from these plants are also described.

Animals↗
PubMed1988

Myringoplasty with three meatal flaps.

A preliminary report on a technique of myringoplasty is presented with the idea of minimizing graft rejection, and to combat anterior blunting and lateralization of the graft. The grafts were generally stable and mobile. Out of 200 cases there was only a 2 per cent rate of graft rejection, with no evidence of anterior blunting or lateralization. The hearing improved considerably. The technique is simple and relatively quick.

Female↗
PubMed1988

Diffuse cerebrospinal gliomatosis: clinical and radiological findings.

Diffuse cerebrospinal gliomatosis is extremely rare. We report the case of a 47-year-old man who presented with clinical features of intracranial hypertension. He developed ascending paraplegia and died. This latter clinical feature has not previously been reported. Clinical features and diagnostic difficulties are discussed.

Brain Neoplasms↗
PubMed1985

Femoral herniae in children.

A series of 12 femoral herniae in children is presented. Nine were misdiagnosed, eight as inguinal hernia. Nine were reducible. The sex incidence, M:F was 7:5 and nine presented between the ages of 8 and 10 years. One presented as intestinal obstruction due to a Richter's hernia and two had had a previous ipsilateral inguinal hernia repaired. All but one were repaired by herniorrhaphy.

Child↗
PubMed1985

Young childhood diarrhoea management by mothers and village practitioners in rural Bangladesh.

The role and success of mothers and village practitioners in treating diarrhoeal episodes have been evaluated in Bangladesh in 1979-1980 in 11 villages with 1801 children under age 5. Diarrhoeal episodes were recorded by weekly house-to-house visits. Among the study children, 1079 diarrhoeal episodes occurred during one year's observation. The attack rate was 60 per 100 children per year. Mothers treated more total episodes and more watery diarrhoea incidences, while practitioners attended more patients with dysentery. The ORS use pattern was significantly higher in watery diarrhoea in children under age 1. Measures are suggested to improve health care delivery to Bangladeshi children with diarrhoea.

Bangladesh↗
PubMed1984

Study of makeshift hospital during cholera outbreak.

This is a report on the study of utilization pattern of a makeshift hospital during a major cholera outbreak, by analyzing data on dehydration status, distance covered, number of deaths averted, and operation-wise comparison with other permanent facilities. To avoid unnecessary deaths due to dehydration and to ensure prompt and adequate care to suddenly accumulated debilitated patients, the makeshift hospital intervened. Subsequent to the intervention, a gradual reduction in patient admissions and cholera case accumulations was noted. Nearly half the cholera cases attending the makeshift hospital came from relatively far (13 + miles). The reporting of the majority (72%) of cholera patients with none-to-mild dehydration indicates an increased awareness of the need for early treatment during a cholera outbreak. Early attendance of diarrhoeal patients probably saved more patients by preventing shock and complications. Para-professionals given a short training accomplished similar efficacy as in a permanent facility. Nearer the affected areas, a simple but effective temporary facility is more effective than a sophisticated facility which is further away and takes several hours to reach, with risk to patients.

Bangladesh↗