PubMed Health⌕ Search

Biomedical subjects

K Zernahle

Publications and source records attributed to K Zernahle.

15 recordsLinked to original sources

Karyotypes and systematics of Asian high-mountain voles, genus Alticola (Rodentia, Arvicolidae). Results of Mongolian-German biological expeditions since 1962, No. 211.

Six species/subspecies of Asian high-mountain voles, genus Alticola, were studied cytogenetically via conventional staining and C- and G-banding. The karyotypes are very similar. The standard karyotype, as in A. strelzovi strelzovi, consists of 56 chromosomes. These are split into 25 acrocentric pairs, one large subtelocentric pair, one small metacentric pair, a large acrocentric X chromosome, and a small Y chromosome, which varies in shape. Constitutive heterochromatin is almost entirely restricted to small centromeric regions. A small submetacentric pair of autosomes in both subspecies of A. semicanus and a medium-sized Y chromosome in A. argentatus severtzovi are of importance in systematics. The data suggest that A. barakshin, A. semicanus, and A. argentatus are separate species.

Animals↗

[Iso-X chromosomes in primary amenorrhoea and Turner's syndrome - presentation by C-banding (author's transl)].

Follow-up checks of conventionally identified iso-X chromosomes have shown dicentric X-chromosomes to be highly involved in mosaic formation (six in eight cases). The assumption is made that the high inclination of dicentric X-chromosomes to non-disjunction may cause maldistribution and, finally, result in mosaic formation. The percentual representation of certain individual lines may be drastically changed by selective gaps and by loss of dicentric X-chromosomes. The instability of dicentric X-chromosomes is a mitotic phenomenon, at the beginning of zygote formation, whereas aberration towards dicentric X or iso-X is a meiotic event.

Amenorrhea↗

[Multiple sex drive abnormalities in a patient with Klinefelter's syndrome].

The authors report various sexual instinct disturbances and, more specifically, exhibitionism and pedophilia of a 25-year-old patient with Klinefelter's syndrome. The patient had committed several punishable offenses and was referred to our specialty clinic for psychologic and psychiatric examinations. Aspects of psychopathology and causal etiopathogenetic relationships of the authors' own observations are discussed and compared with those reported in the literature. Environmental factors are considered to be primarily responsible for the development of sexual perversions. The Klinefelter syndrome as such may be regarded as being of predispositional importance only.

Adult↗