Transient formed visual hallucinations following macular hole surgery.
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Biomedical subjects
Publications and source records attributed to K-G Au Eong.
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AIM: To ascertain the utility values of myopic teenage students in Singapore. METHODS: Children (n=699) aged 15-18 years with myopia (spherical equivalent (SE) at least -0.5 dioptres (D)) in two high schools in Singapore were recruited. Information on time trade-off (years of life willing to sacrifice for treatment of myopia) and standard gamble for blindness (risk of blindness from therapy willing to sacrifice for treatment of myopia) utility values, demographic, and socioeconomic status data were obtained. RESULTS: The time trade-off and standard gamble for blindness utility values were 0.93 (95% confidence interval (CI) 0.93 to 0.94) and 0.85 (95% CI 0.84 to 0.86), respectively. Children with presenting better eye logMAR visual acuity >0.3 had lower time trade-off utility values (mean 0.92 versus mean 0.94), after adjusting for race and sex. There were dose-response relations between standard gamble for blindness values and total family income, as well as both utility values and educational stream (all p values for trend <0.01), after controlling for the same factors. CONCLUSION: The utility values in myopic students were higher for teenagers with better presenting visual acuity, children who wore spectacles or contact lenses, higher total family income, more "academic" schooling stream, and who were non-Muslims.
Previous studies have evaluated the efficacy of several interventions to decrease the progression of myopia. These include devices that alter the perception of the visual environment and pharmacological treatments. There is no conclusive evidence thus far that alteration of the pattern of spectacle wear, bifocals, ocular hypotensives, or contact lenses retards the progression of myopia. Several randomised clinical trials have demonstrated that the rate of progression of myopia is lower in children given atropine eye drops than those given placebo. However, atropine is associated with short term side effects such as photophobia and possible long term adverse events including light induced retinal damage and cataract formation. Other more selective antimuscarinic agents such as pirenzipine are presently being evaluated. Further well conducted randomised clinical trials with large sample sizes and adequate follow up designed to evaluate treatments to retard the progression of myopia should be conducted, since the identification of an effective intervention may have a greater public health impact on the burden and morbidity from myopia than the few treatments currently available.