Biomedical subjects

KA Kang

Publications and source records attributed to KA Kang.

2 recordsLinked to original sources

PubMed1999

Isolation of a novel microorganism, pestalotia heterocornis, producing paclitaxel

Pestalotia heterocornis was isolated from soil collected in yew forest and was shown to produce paclitaxel in semisynthetic liquid media. The presence of paclitaxel in the fungal extract was confirmed by FAB mass spectrometry and NMR spectroscopy. The maximum yield of paclitaxel was 31 &mgr;g per liter. Optimal paclitaxel production occurred after 5-7 days in a 20-liter scale fermentation at 23 degrees C. These results indicate that P. heterocornis is an excellent candidate for consideration in fermentation technology. Copyright 1999 John Wiley & Sons, Inc.

Journal Article↗

PubMed1999

Determination of a biological absorber depth utilizing multiple source-detector separations and multiple frequency values of near-infrared time-resolved spectroscopy

Visualization of the photon path in scattering media is attempted through the use of frequency response analysis of near-infrared time-resolved spectroscopy (NIR-TRS) spectra. The effect of the source-detector distances and the modulation frequency on the photon path is examined. It was found that the use of multifrequency information could lead to the possibility of obtaining the information of an absorber's depth without increasing the number of measurements.

Journal Article↗