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Biomedical subjects

Karel terBrugge

Publications and source records attributed to Karel terBrugge.

3 recordsLinked to original sources

Complications of embolization of arteriovenous malformations of the brain.

OBJECT: The goal of this study was to determine the rates of mortality and morbidity associated with the embolization of arteriovenous malformations (AVMs) of the brain and to analyze the factors related to embolization-related complications. METHODS: The University of Toronto Brain Vascular Malformation Study Group database was reviewed. Three hundred six patients underwent 513 embolization sessions between November 1984 and September 2002. The combined rate of death and any permanent disabling neurological deficit was 3.9% per patient. Location of the AVM in an eloquent part of the brain, presence of a fistula, and a venous deposition of glue were related to complications. A clinically important reduction in the rate of death and disabling morbidity occurred in the second half of the study period. CONCLUSIONS: Embolization of AVMs in the brain is associated with low overall rates of mortality and disabling morbidity.

Adolescent↗

Spinal dural arteriovenous fistula localization with a technique of first-pass gadolinium-enhanced MR angiography: initial experience.

Nine patients with initial magnetic resonance (MR) imaging and clinical findings suggestive of spinal dural arteriovenous fistula (AVF) underwent spinal MR angiography with an autotriggered elliptic centric ordered three-dimensional gadolinium-enhanced technique (hereafter, this MR angiographic technique) before conventional intraarterial angiography. In all nine patients, findings with this MR angiographic technique correctly and precisely localized the spinal dural AVF. Observer error resulted in one case in which the site of the fistula was not prospectively reported but was easily identified retrospectively on the spinal MR angiogram.

Adult↗

The developing stroke: management decisions.

Radiologists have become important members of a multidisciplinary team aimed at treating stroke. New studies such as the NINDS (National Institute of Neurological Disorders and Stroke) intravenous and PROACT II (prolyse in acute cerebral thromboembolism II) intra-arterial thrombolytic trials for acute stroke have focused attention on the need for rapid management. Radiologists play a key role in the diagnosis and selection of patients who may benefit from these therapies. We review current issues in the computed tomographic and magnetic resonance imaging diagnosis of acute stroke and the data supporting the various treatment options.

Acute Disease↗