Karen Chia-Ren Lin | PubMed Health

PubMed2003

Generalized Kohonen's competitive learning algorithms for ophthalmological MR image segmentation.

Kohonen's self-organizing map is a two-layer feedforward competitive learning network. It has been used as a competitive learning clustering algorithm. In this paper, we generalize Kohonen's competitive learning (KCL) algorithm with fuzzy and fuzzy-soft types called fuzzy KCL (FKCL) and fuzzy-soft KCL (FSKCL). These generalized KCL algorithms fuse the competitive learning with soft competition and fuzzy c-means (FCM) membership functions. We then apply these generalized KCLs to MRI and MRA ophthalmological segmentations. These KCL-based MRI segmentation techniques are useful in reducing medical image noise effects using a learning mechanism. They may be particularly helpful in clinical diagnosis. Two real cases with MR image data recommended by an ophthalmologist are examined. First case is a patient with Retinoblastoma in her left eye, an inborn malignant neoplasm of the retina frequently metastasis beyond the lacrimal cribrosa. The second case is a patient with complete left side oculomotor palsy immediately after a motor vehicle accident. Her brain MRI with MRA, skull routine, orbital CT, and cerebral angiography did not reveal brainstem lesions, skull fractures, or vascular anomalies. These generalized KCL algorithms were used in segmenting the ophthalmological MRIs. KCL, FKCL and FSKCL comparisons are made. Overall, the FSKCL algorithm is recommended for use in MR image segmentation as an aid to small lesion diagnosis.

Algorithms↗

PubMed2002

Segmentation techniques for tissue differentiation in MRI of ophthalmology using fuzzy clustering algorithms.

This paper presents MRI segmentation techniques to differentiate abnormal and normal tissues in Ophthalmology using fuzzy clustering algorithms. Applying the best-known fuzzy c-means (FCM) clustering algorithm, a newly proposed algorithm, called an alternative fuzzy c-mean (AFCM), was used for MRI segmentation in Ophthalmology. These unsupervised segmentation algorithms can help Ophthalmologists to reduce the medical imaging noise effects originating from low resolution sensors and/or the structures that move during the data acquisition. They may be particularly helpful in the clinical oncological field as an aid to the diagnosis of Retinoblastoma, an inborn oncological disease in which symptoms usually show in early childhood. For the purpose of early treatment with radiotherapy and surgery, the newly proposed AFCM is preferred to provide more information for medical images used by Ophthalmologists. Comparisons between FCM and AFCM segmentations are made. Both fuzzy clustering segmentation techniques provide useful information and good results. However, the AFCM method has better detection of abnormal tissues than FCM according to a window selection. Overall, the newly proposed AFCM segmentation technique is recommended in MRI segmentation.

Algorithms↗