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Biomedical subjects

Kasja Rabe

Publications and source records attributed to Kasja Rabe.

4 recordsLinked to original sources

[Medication-overuse headache].

Headache associated with the chronic use of medications has become a significant problem in the management of headache. Typically, patients overusing analgesics suffer from tension headache, whereas those over-using triptans may experience daily migraine-type headaches or an increase in the frequency of migraine attacks. The treatment of choice in such cases is withdrawal of the medication followed as early as possible by medicinal prophylaxis of the primary headache.

Acute Disease↗

Flow-reversal device for cerebral protection during carotid artery stenting--acute and long-term results.

OBJECTIVE: Several types of cerebral (embolic) protection devices have been used in patients undergoing carotid stenting. This study assessed results achieved with a flow-reversal system. METHOD: Carotid stenting was performed in 56 patients (mean age, 68 +/- 9 years). The mean percentage of stenosis was 77%+/- 10%. During the procedure, cerebral protection was achieved by means of balloon occlusion of the common and external carotid artery with use of a Parodi Anti-Emboli System. The patients' neurologic status was assessed during the intervention; at discharge; 1, 6, and 12 months after the procedure; and yearly thereafter. RESULTS: The procedure was technically successful in all cases. One patient had a minor stroke 6 hours after the intervention. No major strokes, deaths, or myocardial infarctions occurred. During long-term follow-up (to 40 months), 2 patients died of a secondary complication after intracerebral bleeding and stroke and 1 died as a result of ventricular fibrillation. Restenosis did not exceed 50% of vessel diameter in any patient. CONCLUSIONS: The acute results indicate that proximal occlusion and flow reversal for cerebral protection during carotid stenting is a safe and effective method. The low restenosis and complication rate during long-term follow-up is in accordance with other series of carotid angioplasty and shows that the occlusion balloons do not cause any long-term side effects.

Acute Disease↗

Carotid artery stenting: state of the art.

Carotid artery stenting (CAS) is growing as an alternative to carotid artery endarterectomy. Nowadays, it is performed routinely in many centers worldwide. Still, it is discussed controversially although several clinical trials have shown equivalency or superiority of catheter treatment at least in high-risk patients. What is still missing is a randomized trial in non-high-risk patients. This is an overview about the completed and ongoing trials as well as the current stent and embolic protection technology.

Angioplasty, Balloon↗

Role of distal protection during carotid stenting.

The most common complication of carotid angioplasty is distal embolization of debris and/or thrombus. The only way to avoid this complication is with the use of embolic protection devices. Several filters, distal balloon occlusion devices, and proximal balloon occlusion devices are available. These devices make it possible to capture arteriosclerotic debris during angioplasty and stenting. During the majority of procedures at least some particles can be retrieved. Therefore there is no doubt that these devices are important for carotid angioplasty. However, due to the low complication rate of carotid angioplasty even without embolic protection devices, large randomized trials are necessary to statistically prove the clinical efficacy of these devices.

Angioplasty↗