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Biomedical subjects

Katarzyna Rotter

Publications and source records attributed to Katarzyna Rotter.

5 recordsLinked to original sources

Prevention of hepatitis B recurrence after liver transplantation.

Over the last decade significant improvement in patient and graft survival has been observed after liver transplantation for hepatitis B virus (HBV)-related liver disease, mostly because of efficient prophylaxis against hepatitis B reinfection. This review discusses different approches in prevention of hepatitis B recurrence in liver recipients including new concepts as vaccination against hepatitis B after liver transplantation. Based on available data combined prophylaxis with hepatitis B immunoglobulin (HBIG) and lamivudine is currently recommended prophylaxis for HBV recurrence after liver transplantation.

Antiviral Agents↗

[Zinc status in ex-intravenous drug users infected by HIV, without clinical presentation of AIDS].

We prospectively studied the serum zinc status and development of HIV infection in HIV infected ex-intravenous drug users (IDUS). It was prospective study of 75 persons (53 HIV infected persons, 22 controls). All patients in this group were observed and examined at baseline and every 3 months. We performed clinical examinations and completed blood counts, chemistry blood examinations, serum zinc level, LCD4 cells count. We found lower serum zinc level in HIV infected patients in comparison with control group. There was no significant difference among serum zinc level in male HIV positive patients in comparison with female HIV positive patients and in HIV infected patients with liver disease and in HIV infected patients without liver disease. In subgroups divided according to the degree of immunity deficiency (according to CDC classification) we do not show characteristic statistical differences in serum zinc level in comparison with control group.

Adult↗

[Autoimmune liver diseases and overlap syndromes--overview of past and present reports].

Autoimmune liver diseases are unique among other liver diseases mainly for its unknown pathogenesis, treatment and prognosis. Within their natural course strong correlation between clinical view and serologic markers (autoimmune hepatitis, primary biliary cirrhosis) or X-ray image abnormalities (primary sclerocholangitis) are observed. Significant diagnostic progress, recently seen, revealed major discrepancies in diagnosing and management of classic types of the diseases, suggesting co-association of their symptoms. This review presents former and most up-to-date reports of such cases in terms of overlap syndromes.

Autoimmune Diseases↗

[Possibility of persistent replication of HBV in patients with serological evidence of virus elimination].

Hepatitis B virus infection remains a major epidemiological health problem worldwide, due to the high prevalence (350 mln new cases per year) and clinical consequences of this infection including chronic hepatitis, liver cirrhosis and primary liver cancer. Two cases of patients with clinical symptoms of chronic hepatitis B without traditional serological markers, pointing to active hepatitis B viral replication, were presented. The diagnosis has been confirmed by molecular methods, typical histopathology of liver biopsy specimens, and biochemical improvement after lamivudine treatment.

Adult↗