Kay Robbins | PubMed Health

PubMed2005

Tracking thymocyte migration in situ.

The dynamic process of thymocyte migration can now be visualized in real-time and in the context of the native thymic environment. With improved computational resources, key information can be extracted from real-time imaging data and the migratory behaviors of developing thymocytes can be quantitated. The extraction and exploitation of three dimensional data through time is providing new insight into the nature and regulation of intrathymic migration. In this review we discuss this interdisciplinary approach and the promise it holds for the study of thymocyte migration in situ.

Animals↗

PubMed2004

Spiral dynamics of pulsating methane-oxygen flames on a circular burner.

A premixed flame stabilized on a circular porous plug burner produces a uniform, steady luminous flame front. Throughout much of the parameter range hydrocarbon-oxygen mixtures form spiral-shaped fronts. In methane-oxygen flames at low pressure, the flame exhibits a sequence of states as a control parameter is decreased. These states include periodic rotation of a spiral front; precession of the spiral front in a direction opposite to its rotation, corresponding to doubly periodic petals-out meandering; and nonperiodic states with intermittent jumps associated with linear excursions of the tip, which occur after the spiral front has reached the boundary of the circular burner. We use Karhunen-Loeve (KL) analysis to find the coefficients of the dominant KL spatial eigenfunctions. Their phase space portraits and power spectra provide a description of the dynamics as flow rates are reduced and the system destabilizes. We discuss how these experimental results relate to previous theoretical studies that assume Euclidean symmetry for the experimental configuration.

Journal Article↗