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Biomedical subjects

Kazufumi Sano

Publications and source records attributed to Kazufumi Sano.

15 recordsLinked to original sources

Delayed extended "midthenar" flap for reconstruction of total fingertip avulsion injury and a proposal of ideal postoperative immobilization for a palmar flap.

Avulsion injury through the base of the distal phalanx of the ring finger with a large projecting tip of exposed bone was treated with delayed extended midthenar flap. The midthenar flap adding delay procedure at the first stage of a consecutive 2-stage operation could provide extended flap length to wrap the large projecting tip of the exposed bone at the second stage. This flap is useful for the middle and ring fingertip injury because motions of the all thumb joints are not restricted during the immobilization period. To reduce immobilization discomfort between the 2 stages of the palmar flap operation, a "relaxed flexion position" immobilization technique devised by the authors is also introduced.

Adult↗

Devastating massive knee defect reconstruction using the cornucopian chimera flap from the subscapular axis: two case reports.

Two cases of successful reconstruction of massive defects around the knee with multiple-island combined flaps based on the subscapular axis are reported. Both defects resulted from aggressive debridement for acute osteomyelitis after open fixation of high-energy fractures around the knee. In Case 1, a four-island combined flap consisting of the scapular flap, the lattissimus dorsi muscle flap, the serratus anterior muscle flap, and the scapular osseous flap, based on the same subscapular axis, was used. Partial bone transport using the Ilizarov apparatus was added as reinforcement of arthrodesis. In Case 2, a five-island combined flap, consisting of the scapular, parascapular flap, the lattissimus dorsi muscle flap, the serratus anterior fascial flap, and the scapular osseous flap, was used. Consequent ankylosis of the knee joint afforded the patient painless full weight bearing without secondary arthrodesis. Multiple-island combined flaps based on the subscapular axis can provide three-dimensional reconstruction of destructive knee defects.

Adult↗

Does a bone deformity of the distal phalanx undergo remodeling after removal of a congenital ectopic nail?: A case with periodic radiographic follow-up.

BACKGROUND: Congenital ectopic nails are rare and are characterized by the presence of nail-like tissue mainly at the tip of a finger or toe. OBJECTIVE: Although the accompanying bone deformity might undergo remodeling after removal of the ectopic nail, it remains unknown whether complete bone remodeling can be eventually achieved, and whether such remodeling is necessary to improve the final cosmetic appearance of the concerned fingertip. METHODS AND RESULTS: Follow-up with periodic radiographic examination for 1 year after surgery in a child with congenital ectopic nail revealed no bone remodeling, despite the satisfactory cosmetic result. CONCLUSION: We conclude that residual bone deformity does not affect the final appearance.

Bone Diseases↗

Proposal of new category for congenital unilateral upper limb muscular hypertrophy.

According to congenital anomalies of the hand and forearm classifications, the common characteristic of overgrowth problems is the skeletal overgrowth of part or all of the hand. Congenital unilateral muscular hypertrophy of the upper extremity has been classified under the overgrowth (gigantism) problems as whole-limb hemihypertrophy. The common characteristic of overgrowth problems is the skeletal overgrowth of part or all of the hand, which is not prominent in these patients. Only 15 cases with this anomaly have been reported since 1962. These patients have abnormal muscles with hypertrophic appearance and changed tendon to muscle length ratio. This type of muscular hypertrophy shows an increase in the number of fibers in transverse section, as also seen in multiply innervated muscles like the sartorius and gracilis in humans. Although this phenomenon has a mosaic type distribution, there is no progression of the muscular hypertrophy during growth period. Hand deformities are not due to a part of progression of the disease but result of imbalance of the extrinsic and intrinsic muscles. The evolutionary changes of skeletal muscles should be investigated to explain this congenital phenomenon and might be classified in a different entity from the present categories.

Child, Preschool↗

Double-strand suturing fixation technique for treatment of acute volar plate avulsion fracture of the base of the middle phalanx.

A new suturing technique for treatment of acute volar plate avulsion fracture of the proximal interphalangeal joint is reported. Because this technique that consists of double-strand suture is rigid enough and never obstructs joint motion, early motion exercise can be allowed. This technique only demands simple skill like conventional K-wire fixation. Furthermore, removal of fixation material is not necessary.

Acute Disease↗

The medial sural MEDIAL GASTROCNEMIUS perforator free flap: an 'ideal' prone position skin flap.

The medial sural MEDIAL GASTROCNEMIUS perforator flap is a potentially large, thin cutaneous flap that encompasses the calf skin territory. Its medial sural vascular pedicle has a long leash of large caliber that simplifies microanastomoses when used as a free flap. Because the identification of the requisite perforators and their subsequent intramuscular dissection is facilitated with the patient in a prone position, this can be an "ideal" skin free flap for the posterior aspect of the body. This is especially true for the lower limb where all surgical morbidity could then be restricted to the ipsilateral extremity. This approach has been used in 5 clinical cases, with success except once when the flap was aborted as a result of anatomic anomalies, which is always a concern with muscle perforator flaps.

Foot Injuries↗

The perforator-based conjoint (chimeric) medial Sural(MEDIAL GASTROCNEMIUS) free flap.

The prototypical conjoint or so-called "chimeric" free flap heretofore has been composed of several large independent flaps, each supplied by a separate major branch, that ultimately arise from a common source vessel. The perforator-based type of chimeric flap is a relatively new concept, usually involving multiple muscle perforator flaps each based on a solitary musculocutaneous perforator, but still arising from the same "mother" vessel. This principle of split cutaneous perforator flaps has been now successfully adapted to the medial suralMEDIAL GASTROCNEMIUS perforator free flap on 2 separate occasions. As a chimeric flap, there was greater flexibility in insetting, and overall flap width may be larger but still narrow enough to allow primary donor site closure; and yet, by definition, only a single recipient site was needed for any microanastomoses. This is further proof that the perforator-based chimeric free flap may be an option for any muscle perforator flap donor site, so that potential donor territories for conjoint flaps have become virtually unlimited.

Adult↗

Venous interruption is unnecessary to achieve an adequate delay in the rat TRAM flap model.

Staged division of any or all inferior dominant pedicles to the human lower transverse rectus abdominis musculocutaneous (TRAM) flap has previously been attempted to invoke the delay phenomenon to enhance the rate of success with the superior-pedicled version, especially for patients at high risk for complications. Regardless of the specific vessels ligated, this has usually been accomplished by division of the source artery and its accompanying vein. Whether division of both vessels is essential remains unclear, however. This issue was investigated by using the authors' standard rat TRAM flap model in 43 female Sprague-Dawley rats, which were randomly assigned to four groups. In group A, both the predominant ipsilateral cranial epigastric artery and the cranial epigastric vein were divided 2 weeks before elevation of the TRAM flap. In group B, only the artery was divided; in group C, only the vein was divided. In an undelayed control group, the TRAM flap was elevated immediately, with no prior pedicle division. The percentages of flap survival in group A (89.3 +/- 7.0 percent) and group B (88.8 +/- 6.5 percent) (both with division of the predominant artery) were significantly greater than that in the control group (64.6 +/- 20.5 percent) (p < 0.001) or that in the group in which the vein alone was divided (73.9 +/- 11.3 percent) (p < 0.01). There was no significant difference between the group that underwent vein division only and the control group (p = 0.102). The clinical implication is that arterial division is critical for TRAM flap delay and that arbitrary venous interruption is unnecessary.

Abdominal Muscles↗

A vertical midline scar is a 'high-risk' factor for maximum survival of the rat TRAM flap.

The presence of any abdominal scar, in addition to obesity, a smoking history, and prior irradiation are considered the major known "risk factors" for predictable success or failure of the lower transverse rectus abdominis musculocutaneous (TRAM) flap. For many, a vertical midline scar has even been considered to be a relative contraindication. The possibility that the scar instead could effect some form of delay or by neovascularization permit reperfusion across the midline might negate this concern. The validity of this hypothesis was tested in 40 Sprague-Dawley (CD) rats using our standard rat TRAM flap model. Every rat initially had a vertical skin incision made from xiphoid to pubis. At a second stage, either immediately or after a delay of 1 week, 2 weeks, or 6 months, a superior-pedicled (dominant) or inferior-pedicled (nondominant) TRAM flap was raised, with five rats in each subgroup. For the inferior-pedicled group, the percentage of ipsilateral (muscle-pedicle half) flap survival approached 75% and had a trend toward greater survival with each increase in the time of delay, but any difference was not statistically significant (F= 0.653, P = 0.538). In the superior-pedicled group, the ipsilateral half of the flap always survived completely. In both groups, the contralateral or opposite side always underwent complete necrosis regardless of pedicle orientation or time constraints. The midline scar did not enhance even unilateral TRAM flap survival when compared with historic controls, and long-term transmidline reperfusion across the scar did not seem to occur. These findings corroborate the clinical observation that only a unilateral TRAM flap would be reliable in the presence of a vertical midline abdominal scar.

Animals↗

Venous "supercharging" augments survival of the delayed rat TRAM flap.

Adequate delay of a pedicled transverse rectus abdominis musculocutaneous (TRAM) flap might not necessarily require interruption of the venous system. The retained ipsilateral deep vein of the dominant pedicle could then be used as a secondary outflow source for potential salvage of a congested flap. A venous "supercharged" rat TRAM flap model has been designed to evaluate the efficacy of this maneuver. Seventy-two female Sprague-Dawley rats (CD) were equally divided into two major groups, differing only in whether a delay by division of the dominant cranial epigastric artery had first been performed. An inferior-based TRAM flap (nondominant) was raised for each rat, with three subsets of 12 rats in each group, ie, with the cranial epigastric vein subsequently divided (group control), retained (supercharged), or retained but the inferior pedicle divided (venous flap). Both supercharged subsets had significantly augmented flap survival when compared with flaps in their group raised without the cranial epigastric vein, whether a delay maneuver had (96 +/- 6% vs 89 +/- 7%; P = 0.012) or not (80 +/- 8% vs 65 +/- 21%; P = 0.034) been performed. Flaps with only a cranial epigastric vein pedicle totally necrosed, implying that the observed enhancement in flap viability was not the result of transformation into a venous flap, but perhaps as a crossover flap where an adjacent venosome was captured. Venous supercharging can be accomplished by inclusion of the ipsilateral dominant deep vein, and should be a consideration in the clinical planning of delay maneuvers and for treatment of the compromised TRAM flap.

Animals↗

The relative importance of the deep and superficial vascular systems for delay of the transverse rectus abdominis musculocutaneous flap as demonstrated in a rat model.

The use of some form of delay maneuver for "high-risk" patients before transfer of the superior pedicled lower transverse rectus abdominis musculocutaneous (TRAM) flap for breast reconstruction has augmented the rate of success in both the experimental and clinical arenas. A common method of vascular delay has been the bilateral division of both the superficial inferior epigastric and deep inferior epigastric vessels. Whether all of these must be divided to adequately effect the delay is unknown. For that matter, the relative importance of the superficial versus the deep vascular systems is unclear. To investigate this uncertainty, a delay was attempted in 61 Sprague-Dawley rats by division of either the superficial inferior epigastric or deep cranial epigastric vessels (the latter is the homologue to the human deep inferior epigastric) in unilateral or bilateral fashion. Division of the contralateral superficial inferior epigastric vessel resulted in significantly greater TRAM flap survival than either ipsilateral or bilateral superficial inferior epigastric vessel division (p = 0.0034 or p = 0.0093, respectively). Division of the ipsilateral or bilateral deep cranial epigastric vessel resulted in significantly greater flap survival than just contralateral deep cranial epigastric vessel division (p = 0.0034 or p = 0.006, respectively). No significant difference was observed between the group having contralateral superficial inferior epigastric or groups with ipsilateral deep cranial epigastric division, implying that either alone would be efficacious to achieve the desired delay effect. This would allow the other vascular system to be retained intact for later potential salvage maneuvers as needed.

Animals↗