A young woman with an eroded plaque on the hand.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to Kenneth J Tomecki.
Explore the source record for details and available documents.
Antibiotics are important agents in dermatologic practice. New drugs have expanded the therapeutic approach to uncomplicated skin infections and complicated infections involving deeper soft tissue or infections that require surgical intervention. This article reviews new antibiotics of dermatologic importance, including daptomycin (cyclic lipopeptide), linezolid (oxazolidinone), quinupristin-dalfopristin (streptogramins), moxifloxacin and gatifloxacin (fluoroquinolones), and dalbavancin and oritavancin, which are presently under investigation.
In addition to the traditional antibiotic choices for skin and skin structure infections, such as beta-lactams, macrolides, and clindamycin, newer broad-spectrum antibiotics are available to treat resistant pathogens that can cause severe infections. The pharmacologic profiles of 3 newer classes of these antibiotics are reviewed briefly, and the role of these agents in treating skin and skin structure infections is discussed.
Ticks, obligate, blood-sucking members of the order Acarina and class Arachnida, are the most common agents of vector-borne diseases in the United States. Ticks play an important role in transmitting viruses, bacteria, spirochetes, parasites, and rickettsia. This article reviews the epidemiology, microbiology, diagnosis, and treatment of the major tick-borne diseases in the United States.