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Biomedical subjects

Kenneth R Foster

Publications and source records attributed to Kenneth R Foster.

10 recordsLinked to original sources

A screening test for the determination of ethylene sensitivity.

Ethephon, which releases ethylene within plant tissues after application, was chosen to perform assessments of the relative sensitivity of crops to ethylene and to determine which stages of plant development were most sensitive. The species chosen were: barley, wheat, oats, canola and field pea, all of which are important crops in the province of Alberta, Canada. Plants were treated with ethephon at one of 7 different stages. Plants were assessed for their vegetative and reproductive growth, including height, biomass, yield and seed quality. Visual symptoms were photographed and documented to compare them with symptoms caused by ethylene applied as a gas. It was concluded that in barley, wheat and canola the late vegetative and early reproductive stages were most sensitive, at least when sensitivity was defined as reductions in yield and quality. As for field pea, ethephon had no effect on yield but did cause increased numbers of pods, which in certain conditions could lead to increased yields. Significant effects on vegetative growth were only observed in the early vegetative stages of development but with no effects on yield. The screening protocol successfully identified sensitive cultivars and growth stages for further investigation of the effects of ethylene exposure.

Air Pollutants↗

In memorium: Herman p. Schwan [1915-2005].

Herman P. Schwan [1915-2005] was a distinguished scientist and engineer, and a founding father of the field of biomedical engineering. A man of integrity, Schwan influenced the lives of many, including his wife and children, and his many students and colleagues. Active in science until nearly the end of his life, he will be very much missed by his family and many colleagues.

Biomedical Engineering↗

Emerging neurotechnologies for lie-detection: promises and perils.

Detection of deception and confirmation of truth telling with conventional polygraphy raised a host of technical and ethical issues. Recently, newer methods of recording electromagnetic signals from the brain show promise in permitting the detection of deception or truth telling. Some are even being promoted as more accurate than conventional polygraphy. While the new technologies raise issues of personal privacy, acceptable forensic application, and other social issues, the focus of this paper is the technical limitations of the developing technology. Those limitations include the measurement validity of the new technologies, which remains largely unknown. Another set of questions pertains to the psychological paradigms used to model or constrain the target behavior. Finally, there is little standardization in the field, and the vulnerability of the techniques to countermeasures is unknown. Premature application of these technologies outside of research settings should be resisted, and the social conversation about the appropriate parameters of its civil, forensic, and security use should begin.

Brain Mapping↗

Modeling thermal responses in human subjects following extended exposure to radiofrequency energy.

BACKGROUND: This study examines the use of a simple thermoregulatory model for the human body exposed to extended (45 minute) exposures to radiofrequency/microwave (RF/MW) energy at different frequencies (100, 450, 2450 MHz) and under different environmental conditions. The exposure levels were comparable to or above present limits for human exposure to RF energy. METHODS: We adapted a compartmental model for the human thermoregulatory system developed by Hardy and Stolwijk, adding power to the torso skin, fat, and muscle compartments to simulate exposure to RF energy. The model uses values for parameters for "standard man" that were originally determined by Hardy and Stolwijk, with no additional adjustment. The model predicts changes in core and skin temperatures, sweat rate, and changes in skin blood flow as a result of RF energy exposure. RESULTS: The model yielded remarkably good quantitative agreement between predicted and measured changes in skin and core temperatures, and qualitative agreement between predicted and measured changes in skin blood flow. The model considerably underpredicted the measured sweat rates. CONCLUSIONS: The model, with previously determined parameter values, was successful in predicting major aspects of human thermoregulatory response to RF energy exposure over a wide frequency range, and at different environmental temperatures. The model was most successful in predicting changes in skin temperature, and it provides insights into the mechanisms by which the heat added to body by RF energy is dissipated to the environment. Several factors are discussed that may have contributed to the failure to account properly for sweat rate. Some features of the data, in particular heating of the legs and ankles during exposure at 100 MHz, would require a more complex model than that considered here.

Adult↗

Biological effects of radiofrequency fields: does modulation matter?

This commentary considers modulation as a factor of potential biological importance in assessment of risk of radiofrequency (RF) energy emitted by communications systems and other technologies. Modulation introduces a spread of frequencies into a carrier waveform, but in nearly all cases this spread is small compared to the frequency of the carrier. Consequently, any nonthermal (field-dependent) biological effects related to modulation must result from interaction mechanisms that are fast enough to produce a response at radiofrequencies. Despite considerable speculation, no such mechanisms have been established. While a variety of modulation-dependent biological effects of RF energy have been reported, few such effects have been independently confirmed. Some widely discussed effects, for example a reported modulation-dependent effect of RF fields on the efflux of calcium from brain tissue, remain controversial with no established biological significance. The lack of understanding of the mechanisms underlying such effects prevents any assessment of their significance for communications signals with complex modulation characteristics. Future research should be directed at confirmation and mechanistic understanding of reported biological effects related to modulation. While modulation should be considered in the design of risk studies involving communications-type signals, it should not compromise other aspects of good study design, such as maintaining adequate statistical power and identifying dose-response relationships.

Calcium↗

Thermal modeling of millimeter wave damage to the primate cornea at 35 GHz and 94 GHz.

Recent data on damage to the primate cornea from exposure to millimeter wave radiation are interpreted in terms of a simple thermal model. The measured temperature increases during the exposures (duration 1-5 s, 35 or 94 GHz, 2-7 W cm(-2)) agree with the model within the variability of the data. The thresholds for damage to the cornea (staining of the corneal epithelium by fluorescein and corneal edema) correspond to temperature increases of about 20 degrees C at both irradiation frequencies. Within the limits of the one-dimensional model, thresholds for thermal damage to the cornea can be predicted for a range of exposure conditions.

Animals↗