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Biomedical subjects

Kenton R Kaufman

Publications and source records attributed to Kenton R Kaufman.

At least 19 recordsLinked to original sources

Does walking in a virtual environment induce unstable gait? An examination of vertical ground reaction forces.

Virtual reality (VR) can induce postural instability in standing and walking, as quantified with kinematic parameters. This study examines the effect of a VR environment on kinetic gait parameters. Ten healthy volunteers walked on an instrumented treadmill in a VR environment and a non-VR environment. In the VR environment, a corridor with colored vertical stripes comprising the walls was projected onto a concave screen placed in front of the treadmill. The speed of the moving image was perceptually equivalent to the speed of the treadmill, creating an illusion that subjects walked through the corridor. Vertical ground reaction forces were sampled. Kinetic parameters that reflect gait stability (weight acceptance peak force, weight acceptance rate, push-off peak force and push-off rate) were compared between the VR and non-VR environments. Subjects walked in the VR environment with increased magnitudes and rates of weight acceptance force and with increased rates of push-off force. Variability in weight acceptance rates and peak forces, and variability in push-off peak forces, were also increased in the VR environment. The gait deviations reflect a compensatory response to visual stimulation that occurs in the VR environment, suggesting that walking in a VR environment may induce gait instability in healthy subjects.

Adult↗

The effect of visual biofeedback on the propulsion effectiveness of experienced wheelchair users.

OBJECTIVE: To determine the effect of visual feedback on the propulsion effectiveness of experienced manual wheelchair users. DESIGN: Controlled trial. SETTING: A motion analysis laboratory. PARTICIPANTS: A convenience sample of 16 healthy men and 2 healthy women with T4-L2 traumatic paraplegia, a mean age of 38+/-9 years, and a mean duration of manual wheelchair-based mobility of 14+/-8 years. INTERVENTION: Propulsion was assessed as the subjects propelled an instrumented wheelchair (with and without visual biofeedback) on a custom-built dynamometer at propulsion intensities of .15 and .25W/kg for 10 minutes. MAIN OUTCOME MEASURES: The primary outcome variable was the fraction of effective force (FEF) (ie, the ratio of effective to total force) applied by the subject to the wheelchair's pushrim. Secondary variables included velocity, stroke frequency, and stroke angle. RESULTS: A 2-factor analysis of variance with repeated measurements was used to detect significant differences between the outcome variables. The FEF ratio was 73.9% without feedback and 72.5% with feedback at the lower-intensity level. Propulsion during the higher intensity condition both with and without feedback resulted in a statistically significant improvement in the FEF (73.9%-78.7% with no feedback, 72.5%-80.2% with feedback), compared with the lower-intensity level. Stroke angle increased from 84.3 degrees to 98.7 degrees and frequency decreased from 66 to 57.8 strokes/min with feedback. CONCLUSIONS: Visual biofeedback may have little utility in improving the force effectiveness of manual wheelchair propulsion in experienced wheelchair users. Experienced wheelchair users may have already optimized their stroke in a manner that balances energy expenditure with stroke efficiency. Other variables such as stroke length and frequency may be more amenable to visual biofeedback.

Adult↗

Effects of ankle-foot orthoses on ankle and foot kinematics in patient with ankle osteoarthritis.

OBJECTIVE: To determine if different foot orthoses have a similar effect on foot kinematics in subjects with ankle osteoarthritis (OA) when walking on various ground conditions. DESIGN: Within-subject comparisons study. SETTING: Biomechanics research laboratory. PARTICIPANTS: Thirteen subjects with unilateral ankle OA. INTERVENTIONS: Custom-made ankle-foot orthosis (AFO), rigid hindfoot orthosis (HFO-R), and articulated hindfoot orthosis (HFO-A) were used by subjects when walking on level, ascending and descending ramp, and side-slope conditions. MAIN OUTCOME MEASURES: The range of motion of the hindfoot (calcaneus relative to tibia) and forefoot (metatarsal relative to calcaneus) was measured using an 8-camera motion analysis system. RESULTS: The AFO and HFO-R provided the best sagittal plane hindfoot motion restriction over all ground conditions (P<.001). The HFO-R allowed the greatest sagittal plane forefoot motion when walking over level (P=.01) and side-slope (P<.02) conditions, the greatest frontal plane forefoot motion walking down the ramp (P=.003), and the greatest transverse plane forefoot motion when walking over level (P=.011) and ramp-ascending conditions (P=.005). The HFO-A restricted motion of the unaffected joint and did not effectively restrict hindfoot motion. CONCLUSIONS: The HFO-R not only provides selective restriction to the ankle-hindfoot motion, but also allows sufficient forefoot motion compared with the AFO. We consider the HFO-R to be the best option of all tested orthoses for treating patients with ankle OA pain arising from ankle motion.

Adult↗

Electromyographic activity in the immobilized shoulder girdle musculature during scapulothoracic exercises.

OBJECTIVE: To quantify the electromyographic activity in the shoulder girdle musculature during scapulothoracic exercises performed in a shoulder immobilizer in asymptomatic men. DESIGN: Descriptive. SETTING: Motion analysis laboratory at a tertiary care center. PARTICIPANTS: Five asymptomatic male volunteers ages 24 to 32 years. INTERVENTION: Fine-wire (supraspinatus, infraspinatus, upper subscapularis) and surface (deltoids, trapezii, biceps, serratus anterior) electrodes recorded electromyographic activity from each muscle during scapular clock, elevation, depression, protraction, and retraction exercises completed during a single testing session in random order. MAIN OUTCOME MEASURE: Mean peak normalized (percentage of maximal voluntary contraction [MVC]) electromyographic activity of each muscle during each exercise. RESULTS: Biceps activity was uniformly low (<20% MVC), whereas upper subscapularis activity was uniformly high (40%-63% MVC). Both scapular depression and protraction elicited low activity (<20% MVC) in the supraspinatus, infraspinatus, anterior deltoid, and biceps brachii muscles, while generally producing greater than 20% MVC activity in the trapezii and serratus. Scapular depression produced the largest serratus anterior activity (47% MVC). CONCLUSIONS: These data are the first to describe the electromyographic activity during scapulothoracic exercises while in a shoulder immobilizer. Based on electrophysiologic data in normal volunteers, our findings suggest that during periods of shoulder immobilization: (1) scapular depression and protraction exercises could potentially be safely performed after rotator cuff repair to facilitate scapulothoracic rehabilitation, (2) all exercises studied could potentially be safe after superior labral anteroposterior shoulder repair, and (3) all exercises studied should be avoided after subscapularis repair. Further investigation in symptomatic individuals may facilitate refinement of these recommendations.

Adult↗

Effects of ankle-foot orthoses on ankle and foot kinematics in patients with subtalar osteoarthritis.

OBJECTIVE: To determine whether different foot orthoses have a similar effect on foot kinematics in subjects with subtalar osteoarthritis (OA) when walking on various ground conditions. DESIGN: Within-subject comparison study. SETTING: Biomechanics research laboratory. PARTICIPANTS: Ten subjects with unilateral subtalar OA. INTERVENTIONS: Custom-made ankle foot orthosis (AFO), rigid hindfoot orthosis (HFO-R), and articulated hindfoot orthosis (HFO-A) were used by subjects walking on level, ascending, and descending ramp, and side slope conditions. MAIN OUTCOME MEASURES: The triplanar range of motion of the calcaneus relative to tibia (hindfoot) and metatarsal relative to calcaneus (forefoot) was measured using an 8-camera motion analysis system when subjects with subtalar OA wore different foot orthoses. RESULTS: Braces tended to perform similarly in reducing motion of the forefoot and hindfoot for all ground conditions when compared with unbraced but wearing shoes. The AFO significantly restricted frontal plane hindfoot motion during ramp descent (P<.01) and on a side slope when the arthritic subtalar joint was higher than the unaffected side (P=.02). The HFO-A provided significant frontal plane hindfoot motion restriction during ramp descent (P<.01) and on a side slope when the arthritic subtalar joint was lower than the unaffected side (P=.03). The HFO-R significantly restricted frontal plane hindfoot motion in all ground conditions except ramp ascent (P<.05). CONCLUSIONS: The HFO-R provides significant subtalar joint motion restriction while walking. The HFO-R may be considered an optimal orthosis for patients with subtalar OA pain arising from subtalar motion.

Adult↗

Consumer opinions of a stance control knee orthosis.

Stance control knee orthoses (SCOs) have become very popular recently. However, there is little information regarding opinions of actual orthosis users. The purpose of this study was to quantify the users' opinions of a SCO, and see whether factors found important for knee orthoses in past studies hold true for a stance control orthosis as well. A standardized survey was employed as part of a larger field trial study of the Dynamic Knee Brace System, a SCO developed by the authors. The Dynamic Knee Brace System scored well in areas of effectiveness, operability, and dependability, but areas in need of improvement included weight, cosmesis, and donning and doffing. These findings match well with previous knee orthosis studies. This study shows that wearing a stance control knee orthosis can be a positive experience for an orthosis user.

Adolescent↗

The impact of overt and subclinical hyperthyroidism on skeletal muscle.

OBJECTIVE: Patients with overt hyperthyroidism (OH) commonly have proximal limb muscle weakness that improves after correction of hyperthyroidism. It is unclear, however, if patients with milder degrees of hyperthyroidism (referred to as subclinical hyperthyroidism or SCH) may also have a degree of muscle weakness. This may have clinical relevance as SCH patients are often elderly and may therefore have concurrent sarcopenia of aging and would represent a previously unrecognized complication of SCH. DESIGN: We measured both thigh strength and cross-sectional area in patients with OH (n = 30) or SCH (n = 24), both prior to treatment of hyperthyroidism and again at 6-9 months after the restoration of a euthyroid state. Euthyroid controls (n = 48) were studied at similar time intervals. MAIN OUTCOME: Prior to treatment, both knee flexor and extensor muscle strength was reduced in both patients with OH and SCH compared to controls (p < 0.05). After treatment all strength measurements improved in the OH group (p < 0.01) while in the SCH group the majority of muscle strength measurements improved (p < 0.05). Midthigh muscle cross-sectional area was reduced in both the OH and SCH group at baseline (p < 0.05) compared to controls and increased significantly following treatment (p < 0.05). There were no significant changes in any parameter in the euthyroid control (EC) group during the study period. CONCLUSIONS: The finding that muscle strength and cross-sectional area are reduced in SCH and improved after treatment lends support for the clinical decision to treat rather than observe this condition. This may have particular relevance to certain SCH patient groups including the elderly who are prone to falls and athletically active younger patients who require optimal skeletal muscle function.

Adolescent↗

Biomechanical efficiency of wrist guards as a shock isolator.

Despite the use of wrist guards during skate- and snowboard activities, fractures still occur at the wrist or at further proximal locations of the forearm. The main objectives of this study were to conduct a human subject testing under simulated falling conditions for measurement of the impact force on the hand, to model wrist guards as a shock isolator, to construct a linear mass-spring-damper model for quantification of the impact force attenuation (Q-ratio) and energy absorption (S-ratio), and to determine whether wrist guards play a role of an efficient shock isolator. While the falling direction (forward and backward) significantly influenced the impact responses, use of wrist guards provided minimal improvements in the Q- and S-ratios. It was suggested based on the results under the submaximal loading conditions that protective functions of the common wrist guard design could be enhanced with substantial increase in the damping ratio so as to maximize the energy absorption. This would bring forth minor deterioration in the impact force attenuation but significant increase in the energy absorption by 19%, which would help better protection against fall-related injuries of the upper extremity.

Adult↗

Foot and ankle kinematics and ground reaction forces during ambulation.

BACKGROUND: Assessing patients with foot and ankle disorders by observation of gait is dependent on the examiner's experience and cannot provide information about three-dimensional movement, forces, or motion of segments of the foot. Gait analysis models usually consider the foot as a rigid body and study the foot and ankle as a unit. These models are adequate to describe ankle sagittal plane mechanics but are limited in their ability to provide accurate analysis in the other planes or of segments of the foot. They are, therefore, less effective for objective assessment of foot and ankle disorders than multisegment foot models. METHODS: We performed gait analysis using foot-specific analysis methods and evaluated kinematics, ground reaction forces, temporal force factors, and time-related gait factors in 20 normal subjects during level walking. Eleven reflective markers were applied to the foot and leg, and ten cameras and force plates were used. Subjects were tested in athletic shoes. RESULTS: A three-segment model was constructed to determine three-dimensional motion in the sagittal, coronal, and transverse planes. This model enabled the determination of calcaneal-tibial (ankle-hindfoot complex) and metatarsal-calcaneal (midfoot) movement in three planes. Ground reaction forces, temporal force factors, cadence, stance time, swing time, and percentage of stance time were determined. CONCLUSIONS: These data provide baseline information for assessment of patients with disorders of the ankle and foot.

Adult↗

Surgical treatment of femoroacetabular impingement: evaluation of the effect of the size of the resection. Surgical technique.

BACKGROUND: In patients with symptomatic hip impingement, surgical resection of the femoral head-neck junction may improve the range of motion and relieve pain. A risk of this procedure is fracture. We evaluated the amount of resection of the anterolateral aspect of the femoral head-neck junction that can be done safely. METHODS: Cadaveric proximal femoral specimens (fifteen matched pairs) were divided into three groups: 10%, 30%, or 50% of the diameter of one femoral neck was removed, and the contralateral femoral neck was left intact to serve as the control. A compressive load was applied directly to the femoral head. Peak load, stiffness, and energy to fracture were compared among the groups. RESULTS: The energy to fracture differed significantly (p = 0.0015) among the 10%, 30%, and 50% resection groups. The peak load after the 50% resection was significantly less (p = 0.0025) than that after the 10% or 30% resection. With the numbers available, there was no significant difference in peak load between the 10% and 30% resections. CONCLUSIONS: Resection of up to 30% of the anterolateral quadrant of the head-neck junction did not significantly alter the load-bearing capacity of the proximal part of the femur. However, a 30% resection significantly decreased the amount of energy required to produce a fracture. Thirty percent should be considered to be the greatest feasible amount of resection because of the change in the pattern of the femoral head-neck response to axial loads that we observed.

Acetabulum↗

Spatiotemporal gait deviations in a virtual reality environment.

Previous research suggests that postural sway in standing increases in virtual reality (VR) environments. This study was conducted to examine whether gait instability is prevalent when people walk in a VR environment. Ten healthy adults participated in the study. Subjects walked on a treadmill in a VR environment and a non-VR environment at each of three walking speeds: 0.9, 1.1, and 1.3 m/s. In the VR environment, an endless corridor with colored vertical stripes comprising the walls was projected onto a hemispherical screen placed in front of the treadmill. The speed of the moving corridor image was matched to the speed of the treadmill to create the illusion that subjects were walking through the endless corridor. Spatiotemporal data during gait were collected with an instrumented treadmill housing two piezoelectric force platforms. Gait parameters reflective of gait instability (stride length, step width, variability in stride velocity, and variability in step width) were compared between the VR and non-VR environments. Subjects walked in the VR environment with reduced stride lengths (p = 0.001), increased step widths (p = 0.001), and with increased variability in stride velocity (p < 0.001) and step width (p = 0.002). The gait deviations suggest that walking in a VR environment may induce gait instability in healthy subjects.

Adult↗

Comparison of subjective and objective measurements of balance disorders following traumatic brain injury.

Patients with mild traumatic brain injury (TBI) often complain of dizziness. However, these problems may be undetected by a clinical exam. Therefore, the purpose of this study was to evaluate the relationships between the subjective and objective measures of balance impairment. Ten patients with TBI (6 men and 4 women) and 10 matched controls participated in this study. Average duration since the TBI was 2.8 years (range 0.4-14.4). Six of the 10 subjects with TBI had abnormal imaging studies. All subjects and controls had a normal neuromuscular exam. Tinetti Balance Assessments were obtained and the TBI group was not significantly different from the control group. The Dizziness Handicap Inventory (DHI) score supported their complaints of "unsteadiness" and "imbalance" from the subjects with TBI. The DHI score was 32 +/- 23 (range 4-68) out of a maximum possible score of 100. Balance was tested using computerized dynamic posturography. The Sensory Organization Test score was significantly lower for subjects who had a TBI (70 +/- 12) compared to the control subjects (80 +/- 8), which indicated that the subjects with TBI had poorer balance than the control subjects. A 13-link biomechanical model of the human body was used to compute the kinematics of the whole body center of mass (COM) while walking on a level surface. The subjects with TBI had significantly less displacement in the anterior/posterior direction, walked significantly slower, had significantly greater medial/lateral sway and velocity than the normal controls, and had significantly greater medial/lateral imbalance. There was a significant relationship between the physical aspects of the DHI and posturography. There was also significant relationship between the physical, functional, and total DHI and the motion of the COM. Overall, the motion of the COM predicted between 42 and 69% of the DHI score. The present study has demonstrated that objective measurements can quantify the patient's functional deficits. Therefore, these objective measurement techniques should be used to assess the clinical complaints of imbalance from patients with TBI.

Adult↗

Evaluating the dynamic performance of a fibre optic pressure microsensor.

The dynamic performance of a new fibre optic sensor intended for measuring physiological fluid pressures is assessed in water. The sensor's sensitivity is evaluated at 23 degrees, 35 degrees and 37 degrees C against a Millar pressure catheter for sinusoidal pressure inputs with frequency ranging from 0.5 to 10 Hz. We found that sensitivity versus frequency is flat to 6 Hz and decreases slightly between 6 and 10 Hz. The sensitivity is slightly lower at 23 degrees C than at 37 degrees C. The reproducibility of measurements is excellent (two separate calibration tests in two consecutive days). The output of the fibre optic system used shows a constant time delay (0.13 s) for all frequencies tested. Experiments suggest that, with current sensor design, its immersion in degassed water prior to use ensures a reliable performance.

Equipment Design↗

Partial weight-bearing gait using conventional assistive devices.

OBJECTIVE: To determine if subjects can offload the right lower extremity to a targeted amount of weight bearing using assistive devices. DESIGN: Case series. SETTING: Motion analysis laboratory. PARTICIPANTS: Ten healthy subjects (5 men, 5 women) without lower-extremity injury and minimal experience using ambulatory aids. INTERVENTIONS: Before data collection subjects were trained by a physical therapist to offload the right lower extremity by 50% by using an assistive device and a bathroom scale for feedback on weight reduction. MAIN OUTCOME MEASURES: Vertical ground reaction force was measured by using forceplates while subjects walked at a self-selected speed by using a 3-point partial weight-bearing (PWB) gait pattern with axillary crutches, forearm crutches, and wheeled walker. We also measured vertical ground reaction force by using a single-point cane. RESULTS: Each gait aid significantly reduced the right lower-extremity peak vertical ground reaction force. Participants were able to achieve the target of approximately 50% weight reduction with the axillary (50% reduction) and forearm (56% reduction) crutches. The wheeled walker resulted in a peak vertical load of 64% of body weight, which was in excess of the target load. A single-point cane produced a peak vertical load of 76% of body weight. CONCLUSIONS: By using a bathroom scale, healthy subjects could be trained to achieve a target goal of 50% PWB with axillary and forearm crutches. A wheeled walker resulted in weight bearing greater than the target of 50% of body weight. Subjects were able to offload the right lower extremity by about 25% of body weight by using a single-point cane.

Adult↗

Gait of stance control orthosis users: the dynamic knee brace system.

Individuals with weak or absent quadriceps who wish to walk independently are prescribed knee-ankle-foot orthoses (KAFOs). New stance control orthosis (SCO) designs automatically release the knee to allow swing phase flexion and extension while still locking the joint during stance. Twenty-one participants were fitted unilaterally with the Dynamic Knee Brace System (DKBS), a non-commercial SCO. Thirteen subjects were experienced KAFO users (average 28 +/- 18 years of experience) while eight were novice users. Novice users demonstrated increased velocity (55 vs. 71 cm/sec, p = 0.048) and cadence (77 vs. 85 steps/min, p < 0.05) when using the DKBS over the traditional locked KAFO. Experienced KAFO users tended to have reduced velocity and cadence measures when using the SCO (p < 0.10). Knee range of motion was significantly greater for the novice group than for the experienced group (55.2 +/- 4.8 vs. 42.6 +/- 3.8 degrees, p = 0.05). Peak knee extension moments tended to be greater for the experienced group (0.29 +/- 0.21 vs. 0.087 +/- 0.047 Nm/kg, p = 0.09). This report describes gait changes during the introductory phase of DKBS adoption. Experienced KAFO users undoubtedly had ingrained gait patterns designed to compensate for walking with a standard locked KAFO. These patterns may have limited the ability of those users from taking full and immediate advantage of the SCO capabilities. Also, alternate SCO systems may engender different results. Comparison studies and longer term field studies are needed to clarify benefits of the various bracing options.

Adolescent↗

Arthrodesis of the shoulder after tumor resection.

UNLABELLED: Functional outcomes of patients with arthrodesis after resection of a shoulder girdle neoplasm are only sparsely reported. Fusion of the shoulder can be done as a primary reconstruction or secondarily for salvage of a failed limb-sparing procedure. We retrospectively reviewed 21 patients at a mean followup of 11 years. In eight patients, arthrodesis was done as the primary reconstruction and in 13 patients as the secondary procedure. There were no local recurrences, and no patient had metastatic disease develop. The overall Toronto extremity salvage and Musculoskeletal Tumor Society scores were 81% (range, 46-97) and 23 points (range, 17-26), respectively. There was no difference with respect to function between patients who had their arthrodesis as a primary or secondary procedure. Eight of 21 patients (43%) had a complication that required major surgical intervention. Shoulder arthrodesis as a limb salvage procedure after tumor resection provides good function independent of whether the procedure is done primarily or secondarily. Because of the high complication rate, future efforts must be directed at surgical methods to decrease such complications. LEVEL OF EVIDENCE: Therapeutic study, Level IV (case series--no, or historical control group). See the Guidelines to Authors for a complete description of levels of evidence.

Adolescent↗

Effect of environmental temperature on shock absorption properties of running shoes.

OBJECTIVE: To determine the effect of temperature changes on the shock attenuation of 4 running shoe shock absorption systems. DESIGN: Prospective. SETTING: Motion analysis laboratory. INTERVENTIONS: The shock attenuation of 4 different running shoes representing common shock absorption systems (Nike Air Triax, Asics Gel Nimbus IV, Adidas a3 cushioning, Adidas Supernova cushion) was measured at ambient temperatures of -20 degrees C, -10 degrees C, 0 degrees C, +10 degrees C, +20 degrees C, +30 degrees C, +40 degrees C, and +50 degrees C. Repeated-measures analysis of variance was used to determine differences between shoes. OUTCOME MEASURES: Shock attenuation as indicated by peak deceleration (g) measured by a mechanical impactor following ASTM Standard F1614-99. RESULTS: Shock attenuation decreased significantly with reduced temperature for each shoe tested. The Adidas a3 shoe exhibited significantly higher peak decelerations (lower shock attenuation) at cold temperatures compared with the other shoes. CONCLUSIONS: Cold ambient temperatures significantly reduce the shock attenuation of commonly used running shoes. These findings have important clinical implications for individuals training in extreme weather environments, particularly those with a history of lower limb overuse injuries.

Athletic Injuries↗

Surgical treatment of femoroacetabular impingement: evaluation of the effect of the size of the resection.

BACKGROUND: In patients with symptomatic hip impingement, surgical resection of the femoral head-neck junction may improve the range of motion and relieve pain. A risk of this procedure is fracture. We evaluated the amount of resection of the anterolateral aspect of the femoral head-neck junction that can be done safely. METHODS: Cadaveric proximal femoral specimens (fifteen matched pairs) were divided into three groups: 10%, 30%, or 50% of the diameter of one femoral neck was removed, and the contralateral femoral neck was left intact to serve as the control. A compressive load was applied directly to the femoral head. Peak load, stiffness, and energy to fracture were compared among the groups. RESULTS: The energy to fracture differed significantly (p = 0.0015) among the 10%, 30%, and 50% resection groups. The peak load after the 50% resection was significantly less (p = 0.0025) than that after the 10% or 30% resection. With the numbers available, there was no significant difference in peak load between the 10% and 30% resections. CONCLUSIONS: Resection of up to 30% of the anterolateral quadrant of the head-neck junction did not significantly alter the load-bearing capacity of the proximal part of the femur. However, a 30% resection significantly decreased the amount of energy required to produce a fracture. Thirty percent should be considered to be the greatest feasible amount of resection because of the change in the pattern of the femoral head-neck response to axial loads that we observed.

Aged↗