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Biomedical subjects

Kevin C Katz

Publications and source records attributed to Kevin C Katz.

4 recordsLinked to original sources

Optimal surveillance culture sites for detection of methicillin-resistant Staphylococcus aureus in newborns.

We describe two outbreaks among newborns, one caused by community-associated methicillin-resistant Staphylococcus aureus (MRSA) and the other by hospital-associated MRSA. The umbilicus, rectum, and nares were tested for colonization. We found that no single body site had optimal sensitivity when tested alone. The combination of umbilical and nasal swabs achieved a sensitivity of >90%.

Humans↗

Verification of the IDI-MRSA assay for detecting methicillin-resistant Staphylococcus aureus in diverse specimen types in a core clinical laboratory setting.

The IDI-MRSA assay has a sensitivity of 96% and a specificity of 96% when used to screen patients at extranasal sites. This verification study used previously unverified swabs and was undertaken in a core medical laboratory using nonmicrobiology technologists trained in sample processing, molecular laboratory work flow, and PCR practice.

Humans↗

Emergence of macrolide resistance in throat culture isolates of group a streptococci in Ontario, Canada, in 2001.

Of 500 group A streptococci isolated from pharyngeal swabs, 72 (14.4%) were macrolide resistant, compared to 2.1% in 1997. Of these, 66 (92%) were of the M phenotype and 6 (8.3%) were of the MLS phenotype. Pulsed-field gel electrophoresis found that two clones, with patterns identical to those of serotypes M1 and M4, accounted for 19.4 and 68.1% of the macrolide-resistant isolates, respectively.

Anti-Bacterial Agents↗