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Kevin K Anbari

Publications and source records attributed to Kevin K Anbari.

2 recordsLinked to original sources

Impaction allografting for massive femoral defects in revision hip arthroplasty using collared textured stems.

We present a prospective study of impaction grafting using collared textured stems in femurs with massive defects (defined as requiring >150 cm(3) of cancellous allograft). Eighteen hips were followed for a minimum of 2 years. Average Harris hip scores increased from 50 preoperatively to 83 at most recent follow-up. Seventeen hips were functioning well at the time of most recent follow-up and exhibited no stem subsidence or aseptic loosening. One hip was associated with visible subsidence and required further revision. Single-photon emission computed tomography analyses performed at an average of 37 months indicated active graft reorganization in all cases studied. Impaction allografting with collared textured stems for massive defects demonstrates good intermediate-term clinical results and may be a useful alternative to allograft stem composites and megaprostheses.

Adult↗

Hemoglobin substitutes.

Orthopaedic patients frequently require blood transfusions to treat peri-operative anemia. Research in the area of hemoglobin substitutes has been of great interest since it holds the promise of reducing the reliance on allogeneic blood transfusions. The three categories of hemoglobin substitutes are (1) cell-free, extracellular hemoglobin preparations made from human or bovine hemoglobin (hemoglobin-based oxygen carriers or HBOCs); (2) fluorine-substituted linear or cyclic carbon chains with a high oxygen-carrying capacity (perfluorocarbons); and (3) liposome-encapsulated hemoglobin. Of the three, HBOCs have been the most extensively studied and tested in preclinical and clinical trials that have shown success in diminishing the number of blood transfusions as well as an overall favorable side-effect profile. This has been demonstrated in vascular, cardiothoracic, and orthopaedic patients. HBOC-201, which is a preparation of cell-free bovine hemoglobin, has been approved for clinical use in South Africa. These products may well become an important tool for physicians treating peri-operative anemia in orthopaedic patients.

Anemia↗