Biomedical subjects

Khalid A Tayeb

Publications and source records attributed to Khalid A Tayeb.

3 recordsLinked to original sources

PubMed2005

Peyronie's disease in diabetic patients being screened for erectile dysfunction.

PURPOSE: We assessed the prevalence of Peyronie's disease (PD) in type 2 diabetic patients who were screened for erectile dysfunction (ED). MATERIALS AND METHODS: A total of 1,133 male diabetic Saudi patients were enrolled in this study. Patients were screened for ED using the International Index for Erectile Function. At the screening time, all patients were also interviewed for sociodemographic data and risk factors for ED and diabetes that included age, obesity, smoking, hypertension, dyslipidemia, ischemic heart disease and psychological disorders. Medical history included diabetes, duration of diabetes and diabetes related complications. The diagnosis of Peyronie's disease was based on a palpable penile plaque or acquired penile curvature. RESULTS: Mean age +/- SD for the study sample was 53.9 +/- 10.8 years. Of the patients, 8.1% were diagnosed as having PD. Penile plaque and curvature were the most common findings. About 75% of the patients had long duration and progressive course of their complaint. Significant associations between PD and both ED and longer duration ED were detected. There were also significant associations between PD and age, obesity, smoking, duration and number of cigarettes smoked per day. Dyslipidemia, psychological disorders and presence of at least 1 risk factor were significantly associated with PD. There were significant associations between longer duration and poor metabolic control of diabetes and PD. CONCLUSIONS: Peyronie's disease was prevalent among diabetic patients being screened for ED. The study offered a quantitative estimate of the prevalence of PD, and investigated the association of main risk factors and comorbidities of diabetes and ED with PD.

Adult↗

PubMed2005

Pattern of endocrinal changes in patients with sexual dysfunction.

INTRODUCTION: Many patients with endocrinal changes (endocrinopathy) have some degrees of sexual dysfunction that necessitate assessment and treatment. AIM: To assess the prevalence, and identify the pattern, of endocrinopathy in patients with sexual dysfunction in our community. METHODS: A total of 1,248 male patients with sexual dysfunction were enrolled in this study. Patients were screened for erectile dysfunction (ED) and sexual desire by the erectile function and the sexual desire domains of the International Index of Erectile Function (IEEF). Patients underwent routine laboratory investigations as well as total testosterone and prolactin assessment. All patients were referred to an endocrinologist for clinical and biochemical assessment of their endocrine function. The evaluation consisted of comprehensive history taking, physical examination, and, as needed, laboratory investigations. RESULTS: Mean ages+/-SD were 51.9+/-12.2 and 52.3+/-11.7 years for patients with and without endocrinopathy, respectively. Of the study population, 23.8% had endocrinopathy. The most frequent endocrinal changes were low testosterone level (15%), hyperprolactinemia (13.7%), and hypothyroidism (3.1%). There were significant associations between endocrinopathy and obesity, smoking, low desire, and premature ejaculation (P<0.05 for each). Also, significant associations were found between low desire and low testosterone level, hyperprolactinemia, and hypothyroidism (P<0.05 for each). Hyperprolactinemia was significantly associated with premature ejaculation (P<0.05) but not with low testosterone level (P>0.05). There was no significant association between endocrinopathy and age, cigarette smoking (number and duration), and ED (duration, severity, type of onset, and progression) (P>0.05 for each). CONCLUSION: Endocrinopathy is not a rare condition among ambulatory patients with sexual dysfunction. This study provides a quantitative estimate of endocrinopathy in ambulatory patients with sexual dysfunction.

Comorbidity↗

PubMed2003

Erectile dysfunction risk factors in noninsulin dependent diabetic Saudi patients.

PURPOSE: We assessed the prevalence of and analyzed risk factors for erectile dysfunction in patients with noninsulin dependent diabetes in Makkah, Saudi Arabia. MATERIALS AND METHODS: A total of 562 male diabetic Saudi patients were enrolled in this study. Patients were screened for erectile dysfunction using the International Index of Erectile Function. At the time of screening patients were also interviewed for sociodemographic data, including age, education, occupation, marital status and smoking. Medical history included diabetes, diabetes related complications, risk factors for diabetes and erectile dysfunction, and current medication. RESULTS: Mean age of the study sample was 53.7 years (range 27 to 84). Of the patients 86.1% had various degrees of erectile dysfunction, including mild in 7.7%, moderate in 29.4% and severe in 49.1%. The prevalence of erectile dysfunction was 25% in patients younger than 50 years, which increased to 75% in those older than 50 years. Of those without erectile dysfunction 70% were younger and 30% were older than 50 years (p = 0.0001). Patients with a history of diabetes of greater than 10 years were 3 times as likely to report erectile dysfunction as those with a history of less than 5 years. Men with poor metabolic control were 12.2 times as likely to report erectile dysfunction as those with good metabolic control. Of diabetic patients with erectile dysfunction 53% had 1 or more diabetic related complications compared with 20.5% with no erectile dysfunction (p = 0.0001). CONCLUSIONS: Erectile dysfunction is common in diabetic Saudi men. This study provides a quantitative estimate of the prevalence of erectile dysfunction and its main risk factors in diabetic Saudi patients.

Adult↗