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Khurshid R Ghani

Publications and source records attributed to Khurshid R Ghani.

14 recordsLinked to original sources
PubMed2006

Plastic within renal pelvis on nephroscopy: a potential hazard during percutaneous nephrolithotomy.

The use of adhesive plastic drapes is common throughout laparoscopic and percutaneous surgery. We report a case in which a significant portion of the plastic drape was translocated into the renal pelvis during tract dilation for percutaneous nephrolithotomy. The complication was recognized only on endoscopy and the plastic successfully removed. The potential for morbidity in other patients in the future remains, and we recommend operators be aware of this unusual, but entirely preventable, complication. We highlight some measures to help avoid and check for this complication before the end of the procedure.

Adult↗
PubMed2005

Trends in reporting Gleason score 1991 to 2001: changes in the pathologist's practice.

OBJECTIVE: The prostate specific antigen (PSA) era has been associated with a grade migration towards moderately-differentiated (Gleason 5-7) prostate cancer. We investigated whether changes in interpretation of the Gleason system could be a contributing factor by reviewing the Gleason scores for prostate cancer in our region. PATIENTS AND METHODS: Records of patients with prostate cancer assigned a Gleason score between 1991-2001 were retrospectively reviewed. We analysed trends in Gleason score, method of diagnosis and age at diagnosis. Following this, 50 cases from the dataset were randomly selected (stratified to contain half Gleason 2-4 reports) and reviewed in a blinded manner by an uropathologist and given a new Gleason score. RESULTS: 2737 patients were diagnosed and given a Gleason score; 1484 by prostate biopsy (PB) and 1172 by transurethral resection of prostate (TURP). 273 radical prostatectomy (RP) specimens were received, although the results of pre-operative biopsies were available in only 192 of these patients. Over time, there was an increase in the proportion of patients with Gleason 5-7, and a significant decrease in reporting of Gleason 2-4 cancer (r2 = 0.81, p < 0.0001). In 1991, 24% of cancers were Gleason 2-4; in 2001 this had decreased to 2.4%. TURP was associated with more Gleason 2-4 reports (23%) compared with PB (13.2%) and RP (9.2%). On blinded review, all Gleason 2-4 reports were upgraded to Gleason 5-7 cancer (p < 0.001). CONCLUSION: Over time, the proportion of Gleason 2-4 prostate cancer reported has significantly decreased. Our study suggests that a change in practice by the pathologist is a significant factor in this grade migration.

Adult↗
PubMed2005

Three-dimensional planning of percutaneous renal stone surgery in a horseshoe kidney using 16-slice CT and volume-rendered movies.

Percutaneous management of calculi within horseshoe kidneys can be difficult because of the abnormal renal anatomy. We report our use of 16-slice CT scans to obtain three-dimensional (3D) volume-rendered (VR) movies of the pelvicaliceal system and stone for planning percutaneous renal stone surgery. The movie is formatted onto a disc, which can be played on a personal computer without additional software. This technique allows user-friendly 3D planning in the operating theatre. Unlike conventional two-dimensional images, the 3D VR movie provides a global appreciation for planning.

Endoscopy↗
PubMed2005

Size matters: a survey of how urinary-tract stones are measured in the UK.

BACKGROUND AND PURPOSE: Stone size forms the basis of management pathways in patients with urolithiasis. We carried out a questionnaire-based audit to find out how stone size is routinely measured by radiologists in the UK. MATERIALS AND METHODS: A series of 831 anonymous questionnaires concerning how stone size is assessed using four imaging modalities--plain abdominal radiograph (KUB film), intravenous urogram (IVU), ultrasound, and CT--were sent to 277 radiology departments. Following the survey, a substudy at our institution compared urologists (N = 10) and radiologists (N = 5) in estimating the size of a large (26-mm) and small (11- mm) calculus on KUB films. RESULTS: Of the questionnaires, 425 were returned, and 421 were analyzed. Of these, 85% were from consultants, 14% from trainees/middle grades, and 1% "unspecified." In total, 92% of the respondents were radiologists (10% uroradiologists) and 8% urologists. Estimation of stone size ("guestimation") from KUB films and IVUs was used by 40% and 36% of radiologists, respectively, whereas graded rulers were used by 57% and 59%, respectively. For ultrasound scans and CT, electronic measurement was the favored method (81% and 73%), but guestimation was still used by 10% and 15%, respectively. When assessing the KUB films and IVU, 59% and 61% of urologists, respectively, also used guestimation. The substudy revealed a significant difference among radiologists in the accuracy of size estimation for the 11-mm stone (mean estimated size 9.6 mm; P = 0.02, one-sample t-test). CONCLUSION: A large proportion of radiologists use guestimation for assessing stone size on KUB films and IVU. Even when electronic measuring aids were available for CT and ultrasonography, guestimates remained prevalent. Our substudy showed that radiologists significantly underestimated the smaller stone.

Diagnostic Imaging↗
PubMed2005

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Periodicals as Topic↗
PubMed2004

Bleeding after transrectal ultrasonography-guided prostate biopsy: a study of 7-day morbidity after a six-, eight- and 12-core biopsy protocol.

OBJECTIVE: To compare, in a prospective study, bleeding (in three categories, i.e. haematuria, haematospermia and rectal) and consultations with the general practitioner (GP), after a six-, eight- or 12-core prostate biopsy, as data on whether taking more prostate core biopsies increases bleeding complications are not conclusive. PATIENTS AND METHODS: Over a 5-year period, patients undergoing outpatient transrectal ultrasonography (TRUS)-guided prostate biopsy (six, eight or 12-core biopsy) completed a self-administered questionnaire. The prevalence and duration of the three bleeding complications and GP or hospital visits for a biopsy-related complication were assessed and compared for the 7 days after biopsy. The contribution of local anaesthetic (LA) injection to bleeding rates was also assessed. RESULTS: Of 1384 patients biopsied, 1000 were given questionnaires and 884 (88%) forms were returned. Of these, 760 were suitable for analysis (307 after six-core, 325 eight-core and 128 12-core biopsies); 351 patients were given LA before biopsy. The prevalence of bleeding complications (six-, eight- and 12-core, respectively) was: haematuria 44%, 41% and 39%; haematospermia 13%, 16% and 12%; and rectal bleeding 17%, 26% and 27%. Rectal bleeding was significantly more prevalent in the eight- and 12-core groups (P = 0.0037 and 0.019). The duration of bleeding was not significantly greater in any biopsy group. Subgroup analysis showed no significant difference in the prevalence and duration of rectal bleeding after LA. About 5% of patients in each group consulted their GP because of a complication and 2.4% consulted because of bleeding. Three men with major complications required hospitalization, of which only one was caused by bleeding. CONCLUSIONS: Only rectal bleeding was more prevalent after taking more than six cores, but the duration was no greater. Giving LA did not affect the rectal bleeding rate. With all strategies the major complication and hospitalization rate was very low.

Adult↗