Biomedical subjects

Kim Fromme

Publications and source records attributed to Kim Fromme.

15 recordsLinked to original sources

PubMed2006

Parenting and other influences on the alcohol use and emotional adjustment of children, adolescents, and emerging adults.

Five articles in a special section of Psychology of Addictive Behaviors are briefly reviewed. With samples spanning an age range of 6 years to college age, the 5 articles examine potential mediators and moderators of psychological adjustment and drinking behavior. These articles illustrate the potential contributions of gender, personality traits, motivational factors, environmental characteristics, and parenting styles on the alcohol use, consequences, and emotional adjustment of children, adolescents, and emerging adults. Strengths and limitations of the different designs and methods are discussed in relation to the specific findings and the potential insights the special section provides.

Adjustment Disorders↗

PubMed2006

Measurement of alcohol-related consequences among high school and college students: application of item response models to the Rutgers Alcohol Problem Index.

The Rutgers Alcohol Problem Index (RAPI; H. R. White & E. W. Labouvie, 1989) is a frequently used measure of alcohol-related consequences in adolescents and college students, but psychometric evaluations of the RAPI are limited and it has not been validated with college students. This study used item response theory (IRT) to examine the RAPI on students (N = 895; 65% female, 35% male) assessed in both high school and college. A series of 2-parameter IRT models were computed, examining differential item functioning across gender and time points. A reduced 18-item measure demonstrating strong clinical utility is proposed, with scores of 8 or greater implying greater need for treatment.

Adolescent↗

PubMed2006

Capturing the moment: innovative approaches to daily alcohol assessment.

This article is a summary of a symposium presented at the 2005 Research Society on Alcoholism annual conference organized by Dan J. Neal and chaired by William R. Corbin. Event-level data, wherein each "event" (e.g., day) is captured as its own data point, capture the complex patterns of drinking and other high-risk behaviors in ways that the typical aggregate approach cannot. Because of their richness, methodologies that incorporate event-level data are becoming more common in alcohol research. At least 3 distinct forms of event-level data can be gathered: retrospective data (those collected on a single occasion, using memory aids to help each participant reconstruct all drinking events over a specific period of time), daily monitoring data (reporting on all events for that day), and momentary assessment (those recorded immediately following a drinking event or in response to a prompt from researchers). The goal of this symposium was to address many issues associated with event-level methodology, as well as demonstrate projects that are currently implementing such innovative data collection. The 4 presentations included in this symposium were "Realizing the Promise and Avoiding the Pitfalls of Retrospective Daily Estimation Assessments of Alcohol Use" by Frances K. Del Boca; "Using Interactive Voice Response Technology to Assess the Alcohol-Victimization Link" by Kathleen Parks, Linda King, and Ann Pardi; "Methodological Issues in Using Personal Data Assistants to Self-monitor Alcohol Consumption" by R. Lorraine Collins, Mark Muraven, and Charlene Vetter; and "Collecting Event-level Data Using the World Wide Web" by Dan J. Neal and Kim Fromme.

Activities of Daily Living↗

PubMed2006

Preliminary data on the association among the serotonin transporter polymorphism, subjective alcohol experiences, and drinking behavior.

OBJECTIVE: Individual differences in subjective responses to alcohol are believed to have a genetic basis and have been associated with increased risk of alcohol-related problems. There are, however, conflicting results from past studies, perhaps owing to differences in subjective alcohol effects by limb of the blood alcohol curve and the passage of time. The current pilot study evaluated relations among serotonin transporter (SERT) genotype, subjective alcohol responses, and drinking behavior across both the ascending and descending limbs of the blood alcohol curve. METHOD: Participants (N=222; 68% male) were administered alcohol (target blood alcohol concentration of .06%) with a subsample (n=86) providing genetic data. Following a social stressor, participants were provided the opportunity to engage in ad libitum alcohol consumption. RESULTS: SERT transporter was not significantly associated with ad lib drinking or subjective alcohol effects at individual time points, although a trend toward a SERT by blood alcohol concentration limb interaction was observed for ad lib drinking. In addition, SERT genotype predicted acute tolerance to alcohol effects, with participants homozygous for the long SERT allele developing acute tolerance more rapidly than other genotypes. CONCLUSIONS: Although SERT genotype was not reliably associated with ad lib drinking behavior, the results suggest that individuals with the long-long (LL) genotype may develop acute tolerance to alcohol effects more rapidly than heterozygotes or individuals homozygous for the short SERT allele.

Affect↗

PubMed2005

Influence of physical attractiveness and alcohol on men's perceptions of potential sexual partners and sexual behavior intentions.

The current research presents the results of 2 related experimental studies designed to evaluate the influence of physical attractiveness and a moderate dose of alcohol on men's perceptions of potential sexual partners and sexual behavior intentions. Analyses revealed significant effects of physical attractiveness on partner perceptions and sexual behavior intentions. Although no main effects of alcohol were observed, alcohol differentially moderated the relations between perceived risk and sexual behavior intentions by limb of absorption. Results suggest that greater attention should be focused on identifying the specific physical characteristics of a potential sexual partner--beyond attractiveness--that influence perceptions of risk and intentions to engage in safer sex behaviors and highlight the importance of assessing limb of absorption in evaluating the complex association between alcohol and risky sexual behavior.

Adult↗

PubMed2005

Developmental considerations for substance use interventions from middle school through college.

This article summarizes a symposium organized by Dr. Elizabeth D'Amico and presented at the 2004 Annual Meeting of the Research Society on Alcoholism in Vancouver, Canada. The four presentations illustrate the importance of creating substance use interventions that are developmentally appropriate for youth. They represent innovative approaches to working with preteens, teenagers, and young adults. Dr. D'Amico's paper describes her research on the development of a voluntary brief intervention targeting alcohol use among middle school students. Findings indicated that by using school and community input, she was able to obtain a diverse a sample of youth across grades, sex, ethnicity, and substance use status. Dr. Ellickson's paper describes her research on Project ALERT, a school-based prevention program for middle school youth. Her findings indicate that Project ALERT worked for students at all levels of risk (low, moderate, and high) and for all students combined. Dr. Wagner's Teen Intervention Project was a randomized clinical trial to test the efficacy of a standardized Student Assistance Program for treating middle and high school students with alcohol and other drug problems. The study provided a unique opportunity to begin to examine how development may impact response to an alcohol or other drug intervention. Dr. Turrisi's paper examined processes underlying the nature of the effects of a parent intervention on college student drinking tendencies. Findings suggested that the parent intervention seems to have its impact on student drinking by reducing the influence of negative communications and decreasing the susceptibility of influences from closest friends. Dr. Kim Fromme provided concluding remarks.

Adolescent↗

PubMed2004

Prevention of heavy drinking and associated negative consequences among mandated and voluntary college students.

The Lifestyle Management Class (LMC) was evaluated as a universal and targeted alcohol prevention program among voluntary and mandated college students. The relative efficacy of peer- and professional-led group interventions was also tested in this randomized, controlled design. LMC participants showed decreases in driving after drinking relative to control participants. Changes in heavy drinking varied as a function of treatment condition, readiness to change, and gender, with a trend toward larger decreases among voluntary LMC participants high in readiness to change and a comparable though nonsignificant advantage for male LMC participants in the mandated sample. The LMC was comparably effective for mandated and voluntary students, with no clear advantage for peer- or professional-led groups.

Achievement↗

PubMed2004

Biological and behavioral markers of alcohol sensitivity.

This article summarizes a symposium that was organized by Dr. Kim Fromme and presented at the 2003 annual meeting of the Research Society on Alcoholism in Ft. Lauderdale, Florida. The four presentations illustrate the emerging technologies and methods that are now being used to investigate the genetic basis of differential sensitivity to alcohol and their behavioral manifestations. Combining human genotyping with laboratory measures of behavior and subjective reports, these presentations represent state-of-the-art approaches to crossing the bridge from the Decade of the Brain to the Decade of Behavior. Dr. De Wit's paper describes her research on the neurobiological basis for individual differences in sensitivity to the stimulant and sedative effects of alcohol. Evidence suggests that activity of the dopaminergic and GABAergic neurotransmitters underlie these stimulant and sedative effects, respectively. Both Drs. Hutchison's and Corbin's papers describe their research on polymorphisms for the serotonin transporter (SLC6A4) as a determinant of the subjective effects of alcohol challenge. Dr. Hutchinson's and Ms. Ray's findings indicate that individuals with the short form of the SLC6A4 alleles (S) demonstrated a low level of response to alcohol, thus supporting previous research that the S allele may be associated with increased risk for alcohol dependence. In contrast, Dr. Corbin did not find a reliable association between the SLC6A4 genotype and subjective response to alcohol. Mr. Cook's and Dr. Wall's paper adds another dimension to this article by presenting research on both the aldehyde dehydrogenase (ALDH2) and alcohol dehydrogenase (ADH2) genetic variants and their association with the alcohol-related flushing response that is prevalent in Asian populations. Dr. David Goldman provides concluding remarks.

Alcohol Drinking↗

PubMed2004

Brief alcohol interventions with mandated or adjudicated college students.

This article summarizes the proceedings of a symposium presented at the 2003 RSA Meeting in Ft. Lauderdale, Florida, organized and chaired by Nancy Barnett. The purpose of the symposium was to present information and efficacy data about approaches to brief intervention with students who get into trouble on their campuses for alcohol and as a result are required to attend alcohol education or counseling. Presentations were (1) Differences Between Mandated College Students and Their Peers on Alcohol Use and Readiness to Change, by Tracy O'Leary Tevyaw; (2) An Effective Alcohol Prevention Program for Mandated College Students, by Kim Fromme; (3) Two Brief Alcohol Interventions for a Referred College Population, by Kate Carey; and (4) Brief Motivational Intervention With College Students Following Medical Treatment or Discipline for Alcohol, by Nancy Barnett. The data presented in this symposium indicated that students who are evaluated or disciplined for alcohol use are on average heavy drinkers who drink more heavily than their closest peers. Brief intervention approaches described by the speakers included group classroom sessions, individual motivational intervention, individual alcohol education, and computerized alcohol education. Reductions in consumption and problems were noted across the various intervention groups. Brief motivational intervention as a general approach with mandated students shows promise in that it reduced alcohol problems in a group of mandated students who were screened for being at risk (in the Borsari and Carey study) and increased the likelihood that students would attend further counseling (in the Barnett study).

Adolescent↗

PubMed2003

Cognitive-behavioral profiles of college risk-takers with Type II and psychopathic personality traits.

Prevention efforts would be enhanced by identification of factors that increase the greater relative risk of some college students for dangerous activities such as heavy drinking, illicit drug use, and unsafe sex. Students with Cloninger's [Science 236 (1987) 410.] "Type II" personality characteristics or with psychopathic traits were compared on indices of drinking and risk-taking, and potential mechanisms of unique behavioral patterns were explored. Freshmen (N=331, 50% male) completed self-report measures from which students with Type II and psychopathic traits were identified and compared with the remaining sample. Students with Type II traits reported heavy drinking and frequent intoxicated risk-taking, whereas students with psychopathic traits reported frequent sober risk-taking. Both groups held strong positive outcome expectancies, yet only those with Type II traits reported weak negative outcome expectancies. Moreover, negative outcome expectancies mediated the relation between Type II traits and intoxicated risk-taking. The collective findings suggest that Type II and psychopathic traits underlie differing behavioral profiles, and that students with Type II traits may take risks when intoxicated due to limited recognition of potential negative behavioral consequences.

Adolescent↗

PubMed2003

Fragmentary blackouts: their etiology and effect on alcohol expectancies.

BACKGROUND: Fragmentary blackouts, or memory loss for intoxicated events that may be later recalled with the provision of cues, are common sequelae of heavy drinking, yet understanding of their characteristics, correlates, and consequences is limited. Consequently, this alcohol-administration study addressed questions regarding the etiology of fragmentary blackouts and their effect on alcohol outcome expectancies. METHODS: A placebo-controlled design addressed the etiology of fragmentary blackouts through assessment of memory formation before and after alcohol consumption. The effect of fragmentary blackouts on prospective beliefs about alcohol was assessed by way of a self-report outcome expectancy questionnaire and a measure of response latency for alcohol concepts presented after beverage consumption. RESULTS: Although participants performed similarly on memory indices before consuming beverages, those who reported past fragmentary blackouts and consumed alcohol displayed marked difficulty with recall of a narrative when this was attempted both during intoxication and after detoxification, as well as with a source memory task presented during intoxication. Those reporting fragmentary blackouts also endorsed stronger outcome expectancies for a range of alcohol effects and exhibited greater accessibility for positive alcohol concepts presented after beverage administration. Further, source recall contributed significantly to the episodic recall both during intoxication and after detoxification, as well as to positive outcome expectancies of those receiving alcohol. CONCLUSIONS: Findings suggest that fragmentary blackouts result from poor retrieval and that individual differences in retrieval emerge after alcohol is consumed. Further, one's recall of source aspects of material-its time and social context-is an important determinant of recall of stimuli and events encountered during intoxication, as well as of prospective expectations for positive alcohol effects. The collective findings expand our understanding of this complex yet common neuropsychological consequence of heavy drinking.

Adult↗

PubMed2003

Fragmentary and en bloc blackouts: similarity and distinction among episodes of alcohol-induced memory loss.

OBJECTIVE: En bloc and fragmentary blackouts are distinguishable forms of alcohol-induced amnesia. The former are instances of full and permanent memory loss for intoxicated events, whereas the latter are episodes for which retrieval of experiences is facilitated by provision of cues. Beyond this nosological difference, little is known about descriptive dimensions of the two blackout types. The current study assessed their characteristics as reported by a group of heavy drinking young adults. METHOD: A sample of 136 young adult volunteers (54% male; mean [SD] age = 22.71 [2.23]) were administered a Time-Line Follow-Back assessment, expanded to gather descriptive information about the occurrence and characteristics of en bloc and fragmentary blackouts. RESULTS: Although overall reporting of blackouts by the sample mirrored rates reported in prior research, prevalence and incidence of fragmentary blackouts were more than threefold those of en bloc blackouts. A surprising finding was that the two blackout types exhibited a similar range and distribution of corresponding blood alcohol concentrations. Most en bloc blackouts involved concurrent use of illicit substances; polysubstance use was reported for few fragmentary blackouts. In addition, subjective evaluations of en bloc blackouts were quite negative, whereas fragmentary blackouts were evaluated as only mildly negative. CONCLUSIONS: Beyond nosological distinctions, en bloc and fragmentary blackouts differ on several descriptive dimensions. The collective findings expand understanding of diversity in experiences that accompany memory loss after drinking.

Adult↗

PubMed2003

Heavy episodic drinking and college entrance.

The college environment appears to encourage heavy drinking. Consequently, correlates of student drinking were assessed at college entrance. First-semester freshmen (N = 520, 54 percent women) completed self-report measures of social affiliation and self/peer drinking for high school and college. Analyses indicated that: 1) increased drinking at college entrance mirrored perceived increases by peers, 2) perceptions of peer drinking were robustly overestimated with women displaying the larger overestimation bias; and 3) social affiliation was associated with men's drinking and moderated its relation to perceived peer drinking at college entrance. These results advance understanding of the manner in which heavy drinking patterns emerge as men and women enter college, and campus programs that consider these factors may better promote health and reduce the harms associated with heavy drinking among college students.

Adolescent↗

PubMed2002

Alcohol use and serial monogamy as risks for sexually transmitted diseases in young adults.

Alcohol and condom use were assessed using global, situational, and event-level analyses in a sample of young adults (N = 305). Results varied by methodology, event, and partner type; an inverse association between alcohol and condom use was found only at the event level. Participants with strong sex-related expectancies used condoms less frequently when drinking at the time of 1st intercourse with their current partner. For most recent event with a regular partner, alcohol use was unrelated to condom use, but gender, relationship duration, and oral contraceptive use accounted for more than 25% of the variance. Thus, alcohol may increase risky sex early in a relationship, whereas partner familiarity and alternate contraceptive use play a larger role as relationships develop.

Adult↗

PubMed2002

Brief prevention for adolescent risk-taking behavior.

AIMS: Despite widespread prevention efforts to decrease adolescent risk-taking, substance use and driving after drinking (DD) are prevalent in the United States. The current study compared the efficacy of an abbreviated version of Drug Abuse and Resistance Education (DARE-A) to a new Risk Skills Training Program (RSTP). DESIGN: Adolescent participation in drinking, drug use, DD and riding with a drunk driver was examined longitudinally. After baseline assessments, adolescents were randomly assigned to the RSTP. DARE-A or a no intervention control group and then completed 2-month post-test and 6-month follow-up assessments. SETTING: Adolescents attended a mid-sized suburban high school. PARTICIPANTS: The sample (N = 300) was comprised of 58% females and the age range was 14-19 years. INTERVENTION: The RSTP was developed to target several risk behaviors and to examine the feasibility of conducting a brief personalized prevention program in a group setting. DARE-A focused on increasing knowledge and understanding the deleterious effects of substance use. MEASUREMENTS: Risk-taking behavior, perception of peer risk-taking and positive and negative alcohol expectancies were assessed. FINDINGS: RSTP participants decreased participation in several risk behaviors at post-test, but reductions were not maintained at 6-month follow-up. The control and DARE-A groups increased their positive and decreased their negative alcohol expectancies. The control group increased their alcohol consumption. CONCLUSIONS: Results suggest that a brief, personalized, group prevention program is a feasible approach to reducing adolescent risk-taking. Strategies must be developed to solidify these positive changes so that they are longer-lasting.

Adolescent↗