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Biomedical subjects

Kishiko Ohkoshi

Publications and source records attributed to Kishiko Ohkoshi.

3 recordsLinked to original sources

[Visual prognosis and prognostic risk factors after photocoagulation for diffuse diabetic macular edema].

PURPOSE: To investigate the efficacy of photocoagulation for diffuse diabetic macular edema. SUBJECTS AND METHODS: One hundred and fifty eyes with diffuse diabetic macular edema were treated by laser photocoagulation (grid pattern photocoagulation, in some instances combined with direct photocoagulation) and followed up more than 1 year. The visual prognosis of these cases was retrospectively studied. RESULTS: The logarithm of the minimum angle of resolution (Log MAR) final visual acuity after photocoagulation was improved more than 0.2 levels in 62 eyes (41%) of a total 150 eyes, and in 60% of 87 eyes in which preoperative visual acuity had been less than 0.5. Average visual acuity after photocoagulation reached a plateau within three months after surgery, and 84% of the eyes with 0.5 or better preoperative visual acuity achieved 0.5 or better final visual acuity. There was correlation between visual prognosis and the following preoperative factors: preoperative visual acuity, hard exudates, fluorescein leakage, grid area, hyperlipidemia, and renal failure. CONCLUSIONS: Grid photocoagulation as a treatment for diffuse diabetic macular edema is effective to improve or maintain visual acuity. Alternative treatment such as vitrectomy should be considered after three-month observation on the outcome of grid photocoagulation.

Adult↗

Changes in corneal curvature in accommodation.

PURPOSE: To determine the changes in corneal curvature in accommodation. SETTING: Department of Ophthalmology, St. Luke's International Hospital, Tokyo, Japan. METHODS: Twenty-eight eyes of 14 healthy volunteers with a mean age of 38.9 years (range 28 to 65 years) were enrolled in this prospective study. Corneal topographies were taken before and during accommodation. Subjects achieved maximal accommodation by gazing at a target letter "A" in front of the eye. Keratometric values (K-values) obtained by topographies before and during accommodation were compared. RESULTS: Steepened corneal curvatures during accommodation were observed with the difference-plot view. Maximum K-values for the central 3.0 mm, 5.0 mm, and 7.0 mm corneal diameters significantly increased by a mean of 0.62 diopters (D) +/- 0.83 (SD) (P =.0005, paired t test), 0.60 +/- 0.90 D (P =.0015), and 0.72 +/- 0.65 D (P<.0001), respectively. Respective minimum K-values significantly increased by a mean of 0.62 +/- 0.83 D (P=.0005), 0.67 +/- 0.68 D (P<.0001), and 0.64 +/- 0.62 D (P<.0001). No statistically significant relationship was found between age and change in K-values. CONCLUSION: The results suggest that changes in corneal curvature in accommodation participate in the mechanism of accommodation.

Accommodation, Ocular↗