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Biomedical subjects

Kristen J Wells

Publications and source records attributed to Kristen J Wells.

4 recordsLinked to original sources

Depression in adults with type 2 diabetes: the role of adherence, body mass index, and self-efficacy.

Considerable evidence links depression with the development and worsening of diabetes, but the factors contributing to this link have not been established. The authors examined the role of adherence, body mass index (BMI), and self-efficacy. Adult patients with Type 2 diabetes (N = 56) completed self-report measures of diet and exercise adherence, diet and exercise self-efficacy, and depression. BMI was obtained from medical records. Path and mediation analyses indicated that both adherence and BMI independently contributed to self-efficacy. Self-efficacy mediated both the association between adherence and depression and the association between BMI and depression. These findings are consistent with the proposal that lower self-efficacy in reaction to adherence failure and higher BMI contributes to depression in adults with diabetes.

Body Mass Index↗

Can an algorithm for appropriate prescribing predict adverse drug events?

OBJECTIVE: To evaluate whether a medication-appropriateness algorithm applied to pharmacy claims data can identify ambulatory patients at risk for experiencing adverse drug events (ADEs) from those medications. STUDY DESIGN: Cohort study. METHODS: We surveyed a random sample of 211 community-dwelling Medicare managed care enrollees over age 65 years who were identified by pharmacy claims as taking a potentially contraindicated medication (exposed enrollees) and a random sample of 195 enrollees who were identified as not taking such a medication (unexposed enrollees). The primary outcome of interest was the prevalence of self-reported events in previous 6 months. RESULTS: Ninety-nine (24.4% of total sample) respondents reported a total of 134 ADEs during the previous 6 months. Exposed enrollees had a significantly higher number of chronic conditions and were taking more prescription and nonprescription medications. However, the higher rate of self-reported ADEs among exposed enrollees was not statistically significant from that of unexposed enrollees (prevalence odds ratio = 1.42; 95% confidence interval [CI] = 0.90, 2.25). Only 1.5% (2/134) of the self-reported ADEs were attributed to a medication from the potentially contraindicated list. Instead, most ADEs were attributed to medications that are commonly used in older patients, including cardiovascular agents (21.6%), anti-inflammatory agents (12.2%), and cholesterol-lowering agents (7.9%). CONCLUSIONS: A medication-appropriateness algorithm using pharmacy claims data was not able to identify a subgroup of enrollees at higher risk of experiencing an ADE from those medications. The vast majority of ADEs were attributable to commonly prescribed medications.

Aged↗

Development and psychometric testing of the prenatal breast-feeding self-efficacy scale.

OBJECTIVE: To develop and evaluate the psychometric properties of a scale measuring prenatal breast-feeding self-efficacy. METHODS: A 20-item scale was administered to a sample of 279 low-income pregnant women. RESULTS: Results from this study provide evidence for internal consistency (Cronbach's alpha = .89) and validity of this measure of prenatal breast-feeding self-efficacy in this population. A factor analysis of the scale indicated 4 themes. The instrument distinguished between women who intended to breast-feed and those who intended to formula feed. CONCLUSION: A valid and reliable scale measuring self-efficacy for breast-feeding during pregnancy may help health care providers design interventions to increase breast-feeding rates.

Adolescent↗

Intrinsic and extrinsic motivation and intention to breast-feed.

OBJECTIVE: To examine the feasibility of using the cognitive evaluation theory to examine pregnant women's intention to breast-feed. METHODS: A questionnaire designed to measure intrinsic and extrinsic motivation was administered to 228 pregnant women. RESULTS: Results provide evidence for reliability and validity of the revised instrument in this population. A factor analysis suggests the instrument measures 2 types of intrinsic motivation, one type of extrinsic motivation, and motivation related to the baby. The instrument distinguished differences in motivation between women who intend to breast-feed and those who intend to formula feed. CONCLUSION: This study helps elucidate motivational factors involved in infant-feeding decisions.

Adolescent↗