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Biomedical subjects

L A Andreĭman

Publications and source records attributed to L A Andreĭman.

At least 19 recordsLinked to original sources
PubMed1992

[The use of hemoperfusion through a suspension of cryopreserved hepatocytes in acute liver failure].

The present work deals with results of intensive therapy and temporary organ substitution by using hemoperfusion through a suspension of living donor hepatocytes in 71 patients with acute hepatic insufficiency. Hemoperfusion was performed through a suspension of fresh living hepatocytes or through a suspension of cryo-conserved (during 60 days) living hepatocytes. Lethality was 37-42%.

Animals↗
PubMed1980

[Evaluation of the functional activity of the liver following its heterotopic transplantation in experimental acute hepatic insufficiency].

The functional activity of the transplanted (additional) liver and its efficiency in the treatment of critical hepatic insufficiency was studied in experiments on dogs. Without an immunosuppression being used the additionally transplanted liver manifests its functional activity in the recipient's organism within 4 days and is able to support the animal's life for 3-4 days.

Acute Disease↗
PubMed1979

[Hemoperfusion through adsorbents as a method of preoperative preparation of patients with severe form of mechanical jaundice].

The method of haemoperfusion through the ion exchange resin and active carbon was used 15 times in 13 patients with heavy forms of mechanical subhepatogenous jaundice. The haemoperfusion was used as a method of preoperative preparation for reduction of hyperbilirubinemia and cholemic intoxication and for prevention of possible postoperative complications. One patient recovered. One patient died of progressing hepatic insufficiency. The rest of the patients were subjected to surgical interventions for the main disease.

Charcoal↗
PubMed1978

[Surgical aspects of a temporary heterotopic transplantation of the liver].

The ways of settling some surgical aspects of a temporary heterotopic transplantation of the liver are analysed in the article. According to the obtained data the placement of the graft into the iliac zone of the abdominal cavity is the most convenient for a temporary heterotopic transplantation of an additional liver. An adequate vascularization of the additional organ can be effected via hepatic artery, which simplifies considerably the removal and replacement of this organ. For a free placement of the graft the weight of the donor should be 2 or 3 times less than that of the recipient.

Animals↗
PubMed1975

[Functional and biochemical parallels in two-stage devascularization of the liver].

Experiments were performed on mongrel dogs. Biochemical changes of the blood and functional disturbances in the organism were studied after a two-stage devascularization of the liver at different periods after the second stage, i.e. after the ligation of the hepatic artery. Early disturbances in the intermediary metabolism were the consequence of the two-stage devascularization, i.e. of the rise of the pyruvate and the lactate, an increase of ammonia in the blood and serum transaminases. Biochemical changes of the blood precede and accompany the encephalopathia and serious hemodynamic disturbances in the organism. The mentioned method was capable of causing hepatic coma.

Acute Disease↗