Overdosage with beta-adrenergic blocking agents.
Explore the source record for details and available documents.
Adrenergic beta-Agonists↗
Biomedical subjects
L A Battersby
Publications and source records attributed to L A Battersby.
Tamoxifen and hypercalcemia.
Explore the source record for details and available documents.
Bone Neoplasms↗
Tamoxifen: an overview of recent studies in the field of oncology.
The safety and efficacy of tamoxifen, administered as a single agent in the palliative treatment of advanced breast cancer, are well-established. The role of tamoxifen as part of combined modality treatment still needs to be fully investigated, as does its usefulness as an adjuvant to mastectomy. The use of tamoxifen for tumors other than those in the breast is as yet not clearly defined. Results currently available in these areas are reviewed here.
Adenocarcinoma↗
Use of tamoxifen in advanced male breast cancer.
Tamoxifen citrate has been administered continuously at various dosages to 31 males with evaluable advanced breast cancer in 16 different centers. There were 15 complete or partial responders (48%) and five patients who were assessed to have achieved disease stabilization. In this series, there were responses in visceral-dominant (five of ten), bone-dominant (two of five), and soft tissue-dominant (eight of 15) disease. Response to tamoxifen appeared to be related to estrogen receptor status and to response to prior or subsequent endocrine therapy, although no firm conclusions can be drawn from such small numbers.
Aged↗