[Early stages of prostate cancer].
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Biomedical subjects
Publications and source records attributed to L A Cherkasskiĭ.
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Clinical and morphological evidence obtained for 23 patients with Pickwickian syndrome has been analysed. 18 patients had no other symptoms, 12 patients died of the disease. Standard signs of the syndrome (drowsiness, respiratory distress, diffuse cyanosis, etc.) were not universal, whereas mixed-type respiratory disorders occurred in all the patients as well as right heart hypertrophy, sclerosis and hyalinosis of the lesser circulatory bed found morphologically and histologically.
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The effects of different periods of hypokinesia on the development of 7.12-dimethyl-benzoanthracene-induced osteosarcoma of shinbone were studied in 148 rabbits. The time of induction was found to decrease considerably - from 197.6 to 113.9 days. This may be attributed to hypokinesia's constituting a stress, which involves release of adrenocortical hormones, atrophy of the thymus and reduced cellular immunological vigor.
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Histological assays of the endometrium in females aged over 48 (curettement performed for metrorrhagia, preparations of the corpus uteri cancer and of the uterus, taken from cadavers of persons having no genital lesions) have demonstrated atrophy and transitional mucosa on which background there occurred microadenomatosis foci in some cases. Enhancement of epithelial atypism, its proliferation and larger microadenomatosis foci, microcarcinoma foci allow microadenomatosis to be referred to as precancer proper.
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