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Biomedical subjects

L A Dmitrieva

Publications and source records attributed to L A Dmitrieva.

At least 19 recordsLinked to original sources
PubMed1990

[Changes in the mouth mucosa during local UHF-hyperthermia and radiotherapy of malignant tumors of the maxillofacial region].

Morphological investigations under experimental conditions have demonstrated that local UHF-hyperthermia at 42-43 degrees C for 30 min does not cause alterative changes of the oral mucosa in animals. The revealed signs of activization of metabolic processes can probably increase radiosensitivity of tumors and their reparation. A favorable course of radiation mucositis was noted after experimental local hyperthermia and irradiation. Morphological changes of the oral mucosa, determined mainly by exposure to radiation, are characterized in the early period by alternative and dystrophic changes, and later on (in 3 mos.) by atrophy and sclerosis. In patients local UHF-hyperthermia had a radiosensitizing effect on the oral mucosa at 40-41,5 degrees C for 30 and 60 min. However it did not prevent the completion of a radical split course in the regimen of dynamic dose fractionation nor did it increase the number of postradiation complications. Under this temperature-time regimen the time of development and a degree of expression of radiation reactions did not depend on the succession of hyperthermia and irradiation, and the time of heating.

Adult↗
PubMed1976

[Effect of dexamethasone on RNA synthesis in blood lymphocytes stimulated by phytohemagglutinin].

Phytohemagglutinin (PHA) stimulated RNA synthesis 6 hours after the beginning of incubation of blood lymphocytes in vitro. Dexamethazone in a concentration of 60 mug/ml depressed the RNA synthesis in the blood lymphocytes of donors, treated with PHA, 6 hours after the beginning of cell incubation with the hormone and PHA in vitro. Changes in the action mechanism of the hormone which can lead to the change of sensitivity to glucocorticoids of the same cells at various stages of the cell cycle are analyzed.

Cell Nucleus↗
PubMedDate not supplied

[Changes in dentin permeability for microorganisms during caries treatment].

Effects of a number of chemicals and of the time elapsed since the preparation on dentine permeability for microorganisms were under study. Dentine permeability was found the highest immediately after the preparation and after acid treatment. Potassium oxalate and calcium hydroxide reduced dentine permeability.

Animals↗
PubMedDate not supplied

[Changes in the electric conductivity of the dentin during caries treatment].

Dentin permeability at the bottom of carious cavities of 124 teeth was studied by electrometry. Dentin permeability was found to be higher in deep caries than in moderate-severe and higher in the teeth that had not been treated before than in those filled. Treatment of the cavities with potassium oxalate before filling helped rapidly and effectively lower the dentin permeability in order to prevent involvement of the pulp.

Dental Caries↗
PubMedDate not supplied

[Structural changes in human dentin with the use of modern filling materials].

Changes in human dentin surface structure, effected by potassium oxalate, potassium nitrate, calcium hydroxide, were studied by scanning electron microscopy. Crystal layers of different structures with complete or partial occlusion of the dentin tubes were detected. Complete occlusion was achieved only if potassium oxalate was used.

Calcium Hydroxide↗
PubMedDate not supplied

[A morphological basis for the levels of pulp extirpation and root c anal obturation (experimental morphological research)].

Periapical tissue reaction to root canal filling with zinc-eugenol paste (complete or incomplete filling) was studied in 15 teeth of 5 mongrel dogs after total or subtotal pulp extirpation. Inflammatory reaction developed in all the cases. It was more intensive in cases with total extirpation of the pulp followed by complete or incomplete filling of the root canal than after subtotal extirpation of the pulp followed by root canal filling 1-2 mm below the anatomical apical foramen.

Animals↗
PubMedDate not supplied

[The use of an ortofen-containing paste in the combined treatment of periodontal diseases].

A periodontal dressing for the treatment of gingivitis and periodontitis, characterized by antiinflammatory and antibacterial action, was developed and clinically tried. Application of this dressing cut down the periods of treatment of chronic gingivitis and periodontitis, shortens the period of preparation to surgery, and provides a smooth course of the postoperative period.

Adult↗
PubMedDate not supplied

[The effect of the temperature factor on the structural status of the rat dental enamel].

Effects of various temperature regimens on enamel ultrastructure were examined by scanning electron microscopy in 70 rat incisors. The study has revealed a deep restructuring of the enamel during overheating in the course of tooth preparation, which necessitates the use of appropriate agents for the prevention and correction of the changes developing in dental tissue.

Animals↗