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Biomedical subjects

L A Dmitrieva

Publications and source records attributed to L A Dmitrieva.

54 records · Page 3Linked to original sources

[The effect of the temperature factor on the structural status of the rat dental enamel].

Effects of various temperature regimens on enamel ultrastructure were examined by scanning electron microscopy in 70 rat incisors. The study has revealed a deep restructuring of the enamel during overheating in the course of tooth preparation, which necessitates the use of appropriate agents for the prevention and correction of the changes developing in dental tissue.

Animals↗

[The dental pulp reaction to microbial action in different methods of treating the carious cavity].

Under study were the effects of bacterial stimulation of prepared dentin on dental pulp. Traditional method of drug treatment of prepared cavity with alcohol and either was compared with methods reducing dentin permeability making use of calcium hydroxide, potassium nitrate, and calcium oxalate. Inflammatory reaction of the pulp was more pronounced after traditional treatment. Reduction of dentin permeability with agents blocking dentin tubes reduced the severity of inflammatory reaction.

Animals↗

[The use of taktivin in experimental apical periodontitis exacerbated by a secondary immunodeficiency state].

Apical periodontitis was simulated in 100 white rats with secondary immunodeficiency induced by a single total x-ray irradiation with the RUM [correction of PYM]-17 device. Nonspecific resistance of the rat body was assessed from the neutrophilic phagocytic activity, serum bactericidal activity, lysozyme and complement levels. These parameters were found reduced in the experimental animals; x-ray examinations revealed changes round the dental root apices. Daily injections of tactivin for 10 days in a dose 2-5 mg/kg b.m. resulted in elevation of the nonspecific resistance parameters, and the x-ray picture in this group of animals was the same as in intact controls; therefore, tactivin normalized the immunity system status and indirectly improved the clinical course of apical periodontitis.

Adjuvants, Immunologic↗

[The use of tricalcium phosphate in the vital subtotal extirpation of the pulp].

The authors have proved the desirability of vital subtotal extirpation of the pulp in experiments and clinically. Exposure to tricalcium phosphate transformed the terminal portion of the root pulp into osseocement biologic filling, obturated the apical opening and thus prevented the inflammation in the periodontium and protected it from pathologic exposures.

Adult↗