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Biomedical subjects

L A Doroshenko

Publications and source records attributed to L A Doroshenko.

4 recordsLinked to original sources
PubMed1990

[Microtests for evaluating hemostasis and their clinical value].

A system of microtests, adapted for pediatric practice, has been developed, tested, and proposed for practical use. The system includes 13 microtests, 4 of them meet the requirements of a rapid diagnostic test, the others are used as differentiating and specifying. For the first time three levels of the coagulation status have been distinguished in the newborn: physiologic, border and pathologic; this enables orientation in hemorrhagic and thrombohemorrhagic diseases in the newborn. On the basis of the unified microtests the authors have determined the tactics in early diagnosis and follow-up of newborns suffering from hemorrhage treated outpatiently. The diagnosis was verified under dispensary conditions in 158 (66.6%) children with hemorrhagic diathesis. The results of the investigations described are promising for further improvement of the diagnosis and treatment of hemostasis disorders in newborns with the use of the microtests of new generation.

Blood Coagulation↗
PubMedDate not supplied

[Pre-hospital diagnosis of nosebleed in children].

Early signs of haemorrhages develop in the childhood, nose bleeding being predominant. Recurrent nose bleeding was observed in 130 (89.0%) patients with thrombocytopathies, 37 patients with nasal pathologies, 13 out of 14 children having willebrand's disease, 3 patients suffering from Rendu-Osler disease, in a boy with a factor XIII deficiency, and in a girl with psoriasis. In the case of haemorrhagic diathesis, nose bleeding was, as a rule, combined with haemorrhages of other types (skin, gum, uterine, etc.) whereas in the case of ENT pathology, nose bleeding was the only haemorrhagic symptom. Medical examinations of patients suffering from recurrent nasal haemorrhages at the prehospital stage should include: study of the history case, ENT-doctor examination, and blood analysis using standard tests (micro-coagulation, prothrombin, hemolysate-aggregation). The battery of blood tests can be performed without costly equipment or reagents. It became routine in the work of a regular polyclinical laboratory and helped identify the causes of nose hemorrhages in 94.6% children.

Blood Coagulation Disorders↗