Biomedical subjects

L A Kaminsky

Publications and source records attributed to L A Kaminsky.

24 records · Page 2Linked to original sources

PubMed1987

Plasma volume changes and cardiovascular responses associated with weight lifting.

Ten experienced weight lifters were studied to determine the influence of strenuous, free-weight, squat lift exercise on changes in plasma volume, mean arterial pressure, and the rate pressure product. After a 40-min postural adjustment prior to upright exercise, each subject completed eight sets of eight repetitions of the squat exercise at 55% of the one-repetition maximum. Electrocardiogram heart rate was monitored throughout the test, and blood pressure was determined at the completion of each exercise set. Arterialized capillary blood was drawn during sitting and standing pre-exercise and at the end of the second, fourth, sixth, and eighth sets for the measurement of hemoglobin, hematocrit, and plasma protein concentration, and after the last set for blood lactate. Five additional subjects participated in a postural control comparison. The results of the ANOVA showed a significant loss in plasma volume over the trials which was 2 1/2 times greater than for the control subjects (17.9 vs 7.7% loss) over the same period of time. Exercise rate pressure product increased by 2.85 times resting while only 1.1 times resting for the control subjects. An elevation in mean arterial pressure was found to be correlated to changes in plasma volume, r = -0.98. This study found that plasma volume is reduced while the rate pressure product is increased during the squat lift exercise.

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PubMed1986

Relationships of aerobic capacity and percent body fat with plasma free fatty acid following walking.

We investigated relationships of peak VO2 and percent body fat with postexercise plasma free fatty acid (FFA) and glycerol concentrations in 14 men using multiple-regression techniques. During 1 h of walking (36% of peak VO2), no significant differences in plasma-FFA response were attributed to either peak VO2 or percent body fat. However, individuals with higher peak VO2S tended to have greater elevations in plasma-glycerol concentration during exercise (p = 0.074). They also had greater peak FFA concentrations and FFA X glycerol(-1)-molar ratios immediately after exercise and faster subsequent clearing of excess FFA from the blood (p less than 0.05). Percent fat was not related to postexercise plasma glycerol, FFA, FFA X glycerol-1 responses. Differing postexercise FFA responses, as related to peak VO2, were due, not to varying rates of lipolysis but rather to different rates of FFA mobilization and utilization.

Adipose Tissue↗

PubMedDate not supplied

Reliability of perceived exertion during graded exercise testing in apparently healthy adults.

PURPOSE: Ratings of perceived exertion (RPE) are widely used for monitoring individuals during graded exercise testing. Studies of the reliability of RPEs across various exercise conditions have produced mixed results. The purpose of this study was to assess the reliability of RPEs during graded exercise testing by comparing the perceptual-physiological relationship between the Bruce and Balke treadmill protocols throughout a broad range of relative exercise intensities. METHODS: Thirty-eight middle-aged men and women completed two maximal treadmill graded exercise testing separated by 48 hours. Test order was randomly assigned. RPEs were compared across protocols and between gender at selected exercise intensities using a series of two-way analysis of variances with repeated measures. RESULTS: A comparison of RPEs (Borg 15-point scale) during the graded exercise testing revealed significant protocol and gender differences at 40%, 60% and 80% of maximal heart rate reserve. RPEs were significantly higher during the Balke protocol compared to the Bruce at each intensity (45% = 9.5 +/- 2.0 vs. 8.3 +/- 1.6; 60% = 12.7 +/- 2.4 vs. 11.1 +/- 2.3; 80% = 15.7 +/- 2.2 vs. 14.1 +/- 2.0). In addition, men rated each intensity significantly higher than the women (P < 0.05). CONCLUSIONS: The results from the present study confirm that the perceptual-physiological relationship observed during graded exercise testing varies as a function of the treadmill protocol employed and that these differences extend throughout the exercise training intensity range (40--80% of maximal heart rate reserve) recommended for healthy adults. The perceptual differences between the protocols could not be accounted for by any of the physiological measures assessed within the study. These results have implications when using RPEs from exercise testing for exercise prescription purposes.

Adult↗

PubMedDate not supplied

Validity of rating of perceived exertion during graded exercise testing in apparently healthy adults and cardiac patients.

PURPOSE: Recent exercise guidelines recommend a generalized rating of perceived exertion (RPE) range of 12 to 16 (15-point Borg scale) as the perceptual range associated with a physiological training effect. However, whether an individual who selects an RPE within the generalized range during an graded exercise test or exercise training, is actually within the correlated physiological range (50 to 85% maximum oxygen consumption [VO2max]) has not been studied in large samples of apparently healthy individuals or cardiac patients. The purpose of the present study was to assess the validity of the generalized RPE recommendations in a large heterogeneous group of apparently healthy subjects and cardiac patients. METHODS: Subjects included apparently healthy adults (N = 463) and cardiac patients (N = 217) who presented for a sign-symptom limited maximal graded exercise test (SSLMGXT). Ratings of perceived exertion associated with relative exercise intensities of 60 and 80% of maximal heart rate reserve (MHRR) and peak exercise were selected for analyses. RESULTS: Significant interindividual variability in RPE was observed at both relative exercise intensities (6 to 20 RPE range at 60% MHRR; 8 to 20 RPE range at 80% MHRR) for both populations. Thirty-nine percent of healthy subjects and 32% of cardiac patients reported an RPE outside an 11 to 14 range at 60% of MHRR, whereas 32% of healthy subjects and 52% of cardiac patients reported an RPE outside of a 14 to 17 range at 80% of MHRR. Peak RPE was higher for the apparently healthy subjects compared with the cardiac patients (18.8 +/- 1.2 versus 16.5 +/- 1.8; P < 0.01). CONCLUSIONS: These results challenge the applicability of the generalized RPE recommendations described in recent exercise guidelines under typical clinical exercise testing conditions. The basis for the generalized RPE recommendations warrant further investigation. Those who desire to use RPE as a marker of relative exercise intensity during SSLMGXT should take into consideration the large interindividual variability in these measures.

Adult↗

PubMedDate not supplied

Evaluation of lipid profile measurements obtained from the Cholestech L.D.X analyzer.

BACKGROUND: The Cholestech L.D.X analyzer has the capability of performing a lipid profile in approximately 5 minutes. The purpose of this study was to determine analytical performance capability of the L.D.X to perform lipid profile measurements. METHODS: Forty subjects gave two finger capillary samples and one venous serum which were analyzed in duplicate by two technicians, on two different L.D.X analyzers. A local pathology laboratory was used as the standard for accuracy comparisons. Two controls with known values were provided by the manufacturer to assess within-day precision. Day-to-day precision was determined by analyzing high (240 mg/dL-1 total cholesterol (TC) and 60 mg/dL-1 high-density lipoprotein [HDL]) and low (200 mg/dL-1 TC and 35 mg/dL-1 HDL) human serum samples on 10 different days. RESULTS: Analysis of variance procedures revealed no significant differences between the two technicians or the two analyzers, nor among the fingerstick, venous serum, or reference measures for any of the analytes. The total error of measurement of TC, triglycerides, and HDL measurements were 6.3 to 16.2%, 14.8 to 30.8%, and 11.5 to 26.8%, respectively. In comparison to the National Cholesterol Education Program (NCEP) desirable, borderline-high, and high classifications obtained from the reference laboratory the L.D.X TC results were correctly classified in 92.5% of the cases. L.D.X triglyceride classifications of desirable, borderline hypertyglyceridemia, and distinct hypertriglyceridemia matched 100% with the classifications obtained from the reference laboratory. CONCLUSIONS: Although the Cholestech L.D.X analyzer did not consistently meet NCEP standards for acceptable total measurement error of TC, HDL, and triglyceride analyses, it seems capable of providing reasonable lipid profile measures in both a screening setting and a clinician office where the goal is correct classification of patients' results.

Blood Chemical Analysis↗

PubMedDate not supplied

Evaluation of a new standardized ramp protocol: the BSU/Bruce Ramp protocol.

BACKGROUND: Because of recent technological advances, exercise testing laboratories now have the ability to use ramp protocols with treadmill exercise tests. Since the Bruce protocol is the most widely used treadmill protocol in clinical laboratories, a standardized ramp treadmill protocol was developed that corresponds to the speed and grade settings of the Bruce protocol at each 3-minute time interval. The purpose of this study was to evaluate the utility of using subject demographic and exercise test data to predict peak oxygen uptake (VO2peak) for tests conducted with the BSU/Bruce Ramp protocol. METHODS: Maximal exercise tests were performed by 698 men and women using the BSU/Bruce Ramp protocol. Peak oxygen uptake was measured during all tests. Stepwise multiple regression analyses were used to predict VO2peak (mL.kg-1.min-1) from maximal treadmill test time and selected variables including age, gender, physical activity habits, and body weight. RESULTS: Maximal test time was found to be the most potent predictor of VO2peak, accounting for 86% of the variance in peak aerobic power, with a standard error of estimate of 3.4 mL kg min-1. A multiple regression equation including age, gender, physical activity habits, and body weight resulted in a slightly improved prediction (R2 = 0.88; standard error of estimates = 3.1 mL kg min-1). CONCLUSIONS: Peak oxygen uptake values can be predicted with reasonable accuracy from the BSU/Bruce Ramp protocol. The BSU/Bruce Ramp would be an excellent choice for laboratories desiring to use a ramp treadmill protocol because of the design of the protocol with identical workloads at equivalent time periods (3, 6, 9, 12, 15, 18, 21 minutes) as the commonly used Bruce protocol.

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