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Biomedical subjects

L A Katargina

Publications and source records attributed to L A Katargina.

At least 19 recordsLinked to original sources
PubMed1989

[Variants of pupillary blocks in children with congenital and early acquired uveitis].

Analysis of postuveal complications in 351 children of early age has shown that pupillary block of different type and degree develops in 43% of cases (226 of 526 eyes with uveitis) and more frequently after intrauterine uveitis. In 23.5% of cases, pupillary block is associated with glaucoma, in 44.2%--with normotonia, and in 32.3%--with hypotonia. A clinical and pathogenetic polymorphism of postuveal blocks is shown, three main types of combined pupillary blocks singled out, the connexion with the state of the vitreous body observed. On the basis of dynamic follow-up within 10 years and analysis of results after treatment of 85 eyes, a differential microsurgical approach to treatment is proposed. The usage of adequate surgical intervention allows to achieve a hypotensive and organ-preserving effect, to improve hydro- and hemodynamic indices and the functional state of the eye.

Child, Preschool↗
PubMed1985

[Uveitis].

Explore the source record for details and available documents.

Child↗
PubMedDate not supplied

[Immunoenzyme analysis in the diagnosis of ophthalmic toxoplasmosis].

Enzyme immunoassay (EIA) is a highly sensitive and specific method whose sensitivity is superior to that of the fluorescent antibody test. EIA helped detect IgG antibodies to Toxoplasma in almost 30% of examined adults and children with various ocular diseases, this indicating a high Toxoplasma infection rate in the population. IgM antibodies (indicating an acute infection) were detected in only three children, and Toxoplasma was not the agent of uveitis in these patients. It may be supposed that primary Toxoplasma infection takes place in utero, or the eye is involved long after the primary infection. Bearing this in mind, the authors recommend screening for IgM antibodies in infants aged under 6 months if congenital or acquired Toxoplasma uveitis is suspected.

Adolescent↗
PubMedDate not supplied

[Use of distant thermography in uveitis in children].

Forty-four children aged 6 months to 14 years, suffering from endogenous uveitis of various sites were examined at different phases of the diseases by a scanning type apparatus, AGA-780M-thermographer (Sweden). The results permit a conclusion that long-distance thermography may be effectively used to assess the ocular status even in small restless children. Uveitis active phase was found associated with a hyperthermal reaction in all the examined sites. Hyperthermia was found related to uveitis localization. The authors suggest that thermoasymmetry parameters and the corneolimbic gradient be used as additional objective criteria for the assessment of uveitis activity and dissemination in children.

Adolescent↗
PubMedDate not supplied

[Role of enterovirus infection in the etiology of uveitis in children].

A total of 224 cases with endogenic uveitis in infants are analyzed. The results of complex clinical and immunological analysis and serologic findings bring the authors to a conclusion that enteroviral uveitis makes up 42 percent of all uveitis in children aged under 3 and that this condition is prevalent in this country. Typical late complications, long persistence of virus-neutralizing antibodies in high titers (up to 8-10 years after convalescence) permit a retrospective etiological diagnosis.

Enterovirus Infections↗
PubMedDate not supplied

[Uveitis, caused by Echo-11 virus].

Analysis of clinical manifestations of a total enteroviral infection with ECHO-11 virus-induced uveitis in 58 infants aged 2 weeks to 1.5 years has shown that uveitis develops on days 1-10 of the disease and is associated with a weak injection, endothelial edema, hyperemia and edema of the iris rapidly eventuating in destruction of the pigment lamina and fenestration. Posterior synechiae, pupil deformations, grave uveitis with hypotonia of 4-10 mm Hg are rapidly developing. A two-year follow-up has shown marked hemo- and hydrodynamic disorders, retarded growth of the involved eye, development of grave complications in 60 percent of patients. The most characteristic late complications were iridal fenestration, pseudocoloboma-type pupil deformation, formation of prelental films, often pigmented. The condition is associated with active production of virus-neutralizing antibodies in titers of 1:4 to 1:16384. No relationship between the clinical course and antibody titers was revealed.

Antibody Formation↗
PubMedDate not supplied

[Diagnosis of toxocariasis in uveitis in children].

Seventeen children aged 2 to 13, suffering from uveitis of unknown etiology, were screened for chronic infections, toxocariasis included. Antibodies to Toxocara canis were detected in the blood of two children with negative results of tests for toxoplasmosis, tuberculosis, herpetic and cytomegaloviral infections. One of these two suffered from panuveitis, the other from granulomatous chorioretinitis. Both the clinical forms are characteristic of ocular toxocariasis.

Adolescent↗
PubMedDate not supplied

[The geographical spread of enterovirus uveitis in the USSR].

Enteroviral uveitis is accompanied by intensive and long-term production of specific neutralizing antibodies. The antibody titer to the causative virus ECHO 19/K (Siberia, Krasnoyarsk, 1980-1981) was 1:1000-1:65,000 in 80% of children 5 to 6 1/2 years after the illness. In retrospective examinations of blood sera from children with the history of uveitis using a neutralization test with ophthalmotropic strains of ECHO 19 and ECHO 11 viruses, the ECHO-virus etiology of this disease was first established in 80 patients living in the European part of the country (Moscow, Leningrad, Volgograd, Krasnodar, Donetsk, etc) and in the Caucasus (Yerevan, Tbilisi, Baku). The epidemic process in uveitis is associated with the emergence and alternation of antigenic ECHO virus variants. Both in the Asian and European USSR the causative agent of uveitis in 1979-1983 was ECHO 19/K, in 1980-1987 ECHO 11/A, and in 1986-1989 ECHO 11/B virus. In 1979-1989, altogether over 800 cases of uveitis in children caused by ophthalmotropic variants of ECHO 19 and ECHO 11 viruses were detected in the Soviet Union.

Antibodies, Viral↗
PubMedDate not supplied

[State of the vitreous body in children with congenital uveitis].

Comprehensive examinations of 150 children (229 eyes) with congenital uveitis have revealed vitreous changes in 75.9 percent. The structure of different opacities is presented and relationship between vitreous opacities patterns and subatrophy severity and intraocular pressure parameters detected. Recommendations are given on how to interpret the data of ultrasonic scanning and define the indications for opticoreconstructive surgery.

Child, Preschool↗
PubMedDate not supplied

[Outbreak of enteroviral uveitis in children in Omsk in 1987-1988].

From May, 1987, to July, 1988, 56 cases of acute enterovirus infection complicated by uveitis were reported in Omsk, Western Siberia, USSR. Infants aged from 15 days to 19 months were involved. The infection was nosocomial, the peak of the incidence occurring in January 1988. Severe and moderately severe cases of uveitis (43 out of 56 infants) were prevalent running a course with destruction of the iris, formation of posterior synechias, deformation of the ciliary body, lenticular opacity, appearance of prelental films, retardation of the development of the affected eye, hemorrhages in the fundus of the eye. The causative agent of uveitis outbreak was ECHO-11 virus: 40 strains of ECHO-11 virus were isolated from 27 out of 33 examined infants with uveitis; in 32 out of 33 infants a high titre of antibodies (1:256-1:16384) to the endemic ECHO-11 virus was demonstrated. Uveitis was reproduced in monkeys infected with Omsk strains of ECHO-11 virus. The uveitis outbreak in Omsk is similar in its etiology, epidemiology, and clinical pattern to three previous outbreaks of enterovirus uveitis observed in Krasnoyarsk (central Siberia) observed in 1980-1986.

Disease Outbreaks↗