Biomedical subjects

L A Lantsberg

Publications and source records attributed to L A Lantsberg.

At least 19 recordsLinked to original sources

PubMed1977

[Relationship between the activity of the kallikrein, plasmin and thrombin systems of the blood during intense physical exertion].

The authors studied the changes in the level of precursors of kallikrein, plasmine, and their inhibitors with the aid of a complex method. Blood plasma of sportsmen was examined--of healthy persons and of those with the syndrome of myocardial overstraining under conditions of rest and intensive bicycle ergometric exercises. The results obtained and correlation analysis data pointed to the functional association of the "Hageman's factor system". Sportsmen with the overstrain syndrome displayed an aggravation of the functional possibilities of humoral systems of the hemovascular regulation, this being expressed in a reduced level of the proenzymatic activity and a reduction of the inhibitor values. Correlation of the mentioned indices was disturbed both at rest and during the exercises.

Adult↗

PubMed1976

[Characteristics of changes in the kinin system of blood in hypertensive disease].

The state of the kinin system of blood was studied in terms of its content of kininogen, prekallikrein, kallikrein inhibitor and the spontaneous esterase activity. The examination was conducted in 10 normal individuals and in 81 hypertensive patients with labile and stable arterial pressure and an uncomplicated course. The studies were conducted at rest, during the transfer into an orthostatic position, and after 15 or 60 minutes of walking. The normals demonstrated an activation of the kinin system that ensued in orthostasis, but was more distinct at walking. A significant correlation was noted between the content of prekallikrein and kininogen in all the states under examination. In cases of labile arterial hypertension an increased activation of the blood kinin system was observed at rest, a lack of its activation at walking, and disorders in the correlation between the content of prekallikrein and kininogen. The observed changes in the kinin system may affect the central haemodynamics and the formation of the hyperkinetic type of circulation.

Adolescent↗

PubMed1975

[Certain mechanisms of prophylactic effect of physical training in hypertensive disease].

Physical training produces definite changes in the state of the blood and renal kininine system. In skilled sportsmen the renal kinine system has a higher resistance to the effect of an intensive muscular work than that in physically untrained individuals. At rest the level of the kinine system enzymes in the blood of sportsmen is lower than in untrained persons. On effort sportsmen demonstrate a moderate, but protractedly rising kininogenesis. The functional potentialities of the renal kinine system in sportsmen th hypertensive disease of the I degree continue to be higher than they are in untrained patients. The development of an adequate reaction of the renal and blood kininine system under different conditions appears as one of the mechanisms of the prophylactic effect produced by physical training in hypertensive disease.

Adolescent↗

PubMed1975