PubMed Health⌕ Search

Biomedical subjects

L A Leshchinskii

Publications and source records attributed to L A Leshchinskii.

4 recordsLinked to original sources

[Experience in using helium-neon laser irradiation alone and in the combined therapy of myocardial infarct and other forms of IHD].

349 chronic sufferers from coronary heart disease (functional class II-IV) were exposed to He-Ne laser radiation, received alpha-tocopherol acetate, solcoseryl, mildronate. Alleviation of pain syndrome, quicker increase of exercise tolerance were observed in patients treated with combined regimens: i.v. laser radiation+alpha-tocopherol acetate, i.v. laser therapy+alpha-tocopherol acetate+solcoseryl. Solcoseryl proved efficient against arrhythmia, positive trends in lipid peroxidation were observed in the use of preradiation antioxidants. It is thought valid to use drug "protection" in laser therapy of CHD, especially in growing intensity of the exposure and power of the beam, to control parameters of coagulation, hemostasis, microcirculation and lipid peroxidation.

Adult↗

The dynamics of healing processes in the heart muscle in acute myocardial infarction.

Healing processes in the myocardium in acute myocardial infarction (AMI) were assessed by dynamic monitoring of changes in the levels of collagen metabolites--free (FO) and peptide-bound (PBO) oxyproline--in 50 patients and in 30 healthy controls. Basic parameters of protein metabolism using radionuclide markers were determined simultaneously with FO and PBO values in 33 patients with AMI. The following changes in the blood levels of collagen metabolites were found: FO level increased in the acute stage of MI and correlated with the parameters of protein degradation; PBO level increased in the subacute stage of disease in a close correlation with protein synthesis parameters. Dynamic monitoring of PBO level can thus be used to assess the rate of healing processes in the myocardium.

Adult↗