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Biomedical subjects

L A Moiseeva

Publications and source records attributed to L A Moiseeva.

At least 19 recordsLinked to original sources

[Evaluation of the effectiveness of the use of pefloxacin in combined radiation-thermal injury].

The efficacy of pefloxacin, a novel promising antibacterial drug of the group of fluoroquinolones, was studied on mice against doxycycline in the prevention and treatment of infectious complications of radiation/thermal injury. According to the data on the effect of the antibiotics on the resistance to exogenic infection and the development of dysbacteriosis pefloxacin was recommended for the use in the scheme of combined therapy of radiation/thermal injury.

Animals

[A quantitative analysis of primate motor activity in a situation of delayed spatial choice. The individual behavioral reactions].

Speed of movements in food getting responses of baboons, total time of the response, trajectories of the movements and other parameters revealed obvious changes during formation of conditioned activity. The data obtained suggest that many quantitative characteristics of the primate motor activity are specifically related to various aspects of complex behavioral responses.

Animals

[An analysis of the joint activities of primates in a situation of delayed spatial choice].

A leader-dominant baboon of a couple took practically all the food in the situation of spatial delayed choice. The subdominant baboon managed to get some food, too, using fast changes of behavioral tactics during the experimental session. The obvious negative state of the subdominant baboon resulted in a severe neurotic breakdown. Long delays in the experimental scheme enabled the subdominant to get up to 50% of the food reinforcement due to the dominant baboons mistakes. The role of changes in the tactics of the monkeys is discussed.

Animals

[A comparative neurophysiological analysis of the trace processes in delayed spatial choice and in a trace conditioned reflex in rhesus macaques].

The dynamics of spatial-temporal interrelationships in delayed spatial choice and in differentiation between two conditioned reflexes was studied with the aid of a distant synchronization of electrical activity of prefrontal cortex hippocampus, head of the caudate nucleus and mediodorsal nucleus of the thalamus in 6 rhesus monkeys. A comparative neurophysiological analysis revealed the elements of similarity and difference in the trace processes in both behavioral models which were correlated with the animal behaviour.

Animals

Different neurophysiological mechanisms underlying delayed reaction and trace conditioned reflex.

Electrophysiological study of functional interactions of the prefrontal cortex, the hippocampus, the head of the caudate nucleus and the thalamic medio-dorsal nucleus in 2 monkeys in conditions of the trace reflex and delayed reaction has revealed various morphofunctional systems for these types of memory. The morphofunctional system of the trace CR is characterized by greater stability and a small number of functional connections (21%) in contrast to the dynamic morphofunctional system with a considerable percentage of functional contacts (54%) in case of the delayed reaction. This difference can be very likely related to the different dynamics of functional connections between brain structures rather than to the involvement of various brain structures.

Animals