[Cytological study of wounds using detoxication and nondrug immunomodulation in patients with severe burns].
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Blood↗
Biomedical subjects
L A Palienko
Publications and source records attributed to L A Palienko.
[Status of cell surface of hepatocytes after exposure to carbon tetrachloride].
In order to estimate contact interactions and deformity of the surface of hepatocytes at a toxic hepatitis, produced by means of carbon tetrachloride, a morphometric analysis of ultrastructures of the contacts and retractions of the surface of hepatocytes, formed at an increased intraorganic pressure has been performed. Carbon tetrachloride produces decrease in adhesive interactions of the cellular surfaces in the area of simple connections, decrease in amount of desmosomes and results in increasing deformity of the surface of hepatocytes. These data support that there exists a universal reaction of the intercellular contacts to a damaging action.
Animals↗
[Participation of bone marrow stromal precursor cells and bone regeneration during transosseous osteosynthesis].
Changes in the proliferative activity and in the number of bone marrow stromal precursor cells (SPC) in the dog long bone fixed with Ilizarov's apparatus were studied by cloning in monolayer cultures over a period of leg lengthening. It was demonstrated that in 1-1 1/2-year-old dogs the number of dividing SPC in the tibia increased up to 95% by termination of the distraction (60 days). Concurrently, the colony-forming efficiency (CFE) increased 11-fold. In the contralateral tibia (CFE significantly rose during the distraction, while in the humeri it decreased 2.5-fold as compared to control. A conclusion is drawn about participation of SPC in bone regeneration.
Animals↗
[Dynamics of the count of bone marrow cells forming fibroblast colonies in culture and its relation to osteogenesis activity in the reparative regeneration of the lengthened limb].
A comparative analysis of the number of bone marrow cells forming fibroblastic colonies in culture and of the roentgenological characteristics of bone regenerate during different periods of limb elongation was carried out in dogs. The increase in numbers of colony forming cells in the operated bone and decrease of their number in the intact ones were shown to correspond to the period of active osteogenesis. A distinct negative correlation between the number of colony forming cells in humerus and operated bone is considered as an indirect evidence of the migration of these cells from the intact bones. The number of colony forming cells can be used to estimate quantitatively the intensity of osteogenesis upon reparative regeneration under the conditions of limb elongation.
Animals↗
[Bone marrow hematopoietic function and its relation to osteogenesis activity during reparative regeneration in leg lengthening in the dog].
The cellular composition of bone marrow and peripheral blood was studied in different periods of the formation of bone regenerate between the ends of tibia fragments upon their dosed stretching. The intensive regeneration of a hemopoietic rudiment proceeded during the period of active osteogenesis in the elongated bone. A conclusion is drawn that the cellular composition of bone marrow and peripheral blood can be used as indices of the osteogenesis intensity.
Animals↗