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Biomedical subjects

L A Perry

Publications and source records attributed to L A Perry.

63 records · Page 4Linked to original sources
PubMed1982

Salivary cortisol determination: adaptation of a commercial serum cortisol kit.

The determination of cortisol levels in saliva offers a number of significant advantages as compared with plasma or serum measurements, and radioimmunoassay is the technique of choice because of the greater sensitivity required. To date, the assay of salivary cortisol has been limited to only a few centres employing 'in-house' reagents. We describe some simple modifications of a commercial kit, designed for the assay of cortisol in serum and urine, which allow direct and rapid determination of the steroid in saliva. These modifications enable any laboratory with access to a gamma counter to perform large numbers of salivary cortisol assays at relatively low cost.

Adult↗
PubMed1981

Effects of delivery on fetal unbound cortisol concentration.

Non-protein-bound (free) cortisol in plasma is that fraction of the total plasma cortisol concentration that is generally regarded as biologically active. The concentration of free cortisol in cord vein plasma obtained at delivery was found to be related closely to the total cortisol concentration. After vaginal delivery following spontaneous onset of labor the free cortisol concentration in cord blood was not significantly different from that measured following induced onset of labor. The free cortisol concentration in the cord blood correlated significantly with the duration of the second stage of labor. These changes in the free cortisol concentration in cord plasma, rather than constituting a primary event in the onset of labor, may reflect the stress of vaginal delivery on the fetus.

Cesarean Section↗
PubMed1978

Comparisons of the concentrations of palmitate and cortisol in amniotic fluid for the prediction of pulmonary maturity.

The concentrations of palmitic acid, derived from lecithin, and of cortisol in samples of amniotic fluid collected during the last trimester of human pregnancy, ranged from 28 to 420 mumol/l and from 16 to 104 nmol/l, respectively. There was a weak (r = 0.43) but significant (p less than 0.01) correlation between the concentrations of cortisol and palmitate in the samples. Measurement of the cortisol concentration in amniotic fluid provided an unreliable index of pulmonary immaturity, whether this was assessed with reference to the concentration of palmitate or from subsequent development of the respiratory distress syndrome. Measurement of cortisol in amniotic fluid cannot be recommended for this purpose.

Amniotic Fluid↗
PubMed1978

Plasma prolactin in pregnancy induced hypertension.

In a prospective study, plasma prolactin concentration at 37 to 41 weeks gestation in 45 primigravidae showed a significant correlation with maximal rise in diastolic blood pressure between levels at 7 to 16 weeks and those measured between 28 weeks and delivery.

Female↗
PubMedDate not supplied

The relationship between selected educational outcomes of senior RN-to-BSN students and their choice of advanced placement options available in the Maryland nursing articulation model.

If national standards for entry into practice are to be changed, viable routes to achievement of the BSN must be established in each state. Maryland has implemented a statewide articulation model that allows the registered nurse to obtain credit for work completed at lower division schools through one of three advanced placement options. This study sought to answer the question of whether there is a difference in selected academic outcomes of senior RN-to-BSN students who choose different pathways available in the model. Data were collected from all students (n = 113) completing clinical concepts courses at a large university school of nursing. The independent variables were mode of entry and pattern of study. The dependent variables were scores obtained on the National League for Nursing (NLN) Comprehensive Nursing Achievement Test for Baccalaureate Nursing Students and the grades obtained in the spring and fall nine-credit clinical concepts courses (examinations, formal papers, clinical evaluations). The entry pathway did not make a significant difference in terms of scores on the spring NLN examination, course tests, or paper grades. However, differences were noted in the clinical area. Transition course students achieved the highest mean clinical performance score, and direct transfer students achieved the lowest score. The implication for nursing education is that there appears to be no significant difference in academic achievement of RN-to-BSN students admitted for advanced placement using three different validating procedures.

Adult↗
PubMedDate not supplied

Adrenocortical adenoma--an unusual presentation with hypersecretion of oestradiol, androgens and cortisol.

We describe a 6 year-old boy who presented with bilateral gynaecomastia, pseudoprecocious puberty and facial features suggestive of Cushing's syndrome. The underlying pathology was a right adrenocortical adenoma which was secreting oestradiol, androgens and cortisol. All the biochemical abnormalities normalised within one week of right adrenalectomy. To our knowledge this combination of hormones produced by an adrenocortical adenoma is particularly unusual.

Adenoma↗
PubMedDate not supplied

Self-reported adjustment, chronic sorrow, and coping of parents of children with Down syndrome.

Mothers and fathers of children with Down syndrome were surveyed on overall patterns of adjustment and on frequency of chronic sorrow and coping behaviors. Fathers overwhelmingly (83%) depicted their adjustment in terms of steady, gradual recovery, while the majority of mothers (68%) reported a peaks-and-valleys, periodic crises pattern; chi 2 = 8.64, p less than .01. Mothers also reported higher frequencies for chronic sorrow as well as for behaviors such as self-blame and expression of negative affect. Thus, mothers and fathers in the same family may experience distinct differences in adjustment and coping as parents of a handicapped child.

Adaptation, Psychological↗
PubMedDate not supplied

The Bridge Program: an overview.

Challenging the health manpower requirements of a diverse population is the concomitant need to prepare nurses from underrepresented groups with leadership skills. As the graduate educated nursing population is not congruent with the numbers of minorities in the general population, it is urgent that the academic community address this problem. The Bridge Program is one answer to this concern by a large university system. The Bridge Program provides academic support, mentoring, program enrichment for baccalaureate students from underrepresented groups who possess the ability and desire to pursue advanced nursing study. The preparation includes each student producing a scholarly project developed in collaboration with a research faculty member. These teaching-learning activities are to facilitate minority nursing students' access to the rigors of graduate education.

Education, Nursing, Baccalaureate↗