[Chronic effect of alternating electric field on genetic and morphometric indicators of the body].
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Biomedical subjects
Publications and source records attributed to L A Poliakova.
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Clinico-neurologic and electroencephalographic (EEG) examinations of 149 women suffering from late gestosis, carried out during pregnancy and after labor, have revealed various neurologic syndromes (vegetovascular dystonia, narcoleptic and neuroendocrine syndromes, pyramidal insufficiency syndrome) in all of them; these syndromes correlated with the severity of late gestosis and EEG changes. The detected changes indicated the presence of the hypothalamic syndrome in women suffering from late gestosis, this syndrome being more marked in grave forms of gestosis. The detected neurologic symptoms and EEG changes persisted long after delivery (up to 7 years). The authors emphasize the necessity of timely adequate therapy of women suffering from gestosis, that should include tranquilizers, anticonvulsants, vasoactive and nootropic drugs.
A study was made of the effect of ethacizine administered in a single dose and continuously on myocardial contractility and hemodynamics in 78 patients with coronary heart disease, neurocirculatory dystonia and myocardiodystrophy suffering from impaired cardiac rhythm. In 28 patients, ethacizine was administered in combination with glutamic acid and in 23 with digoxin. In patients with coronary heart disease, particularly in those with heart failure, ethacizine produced a negative inotropic effect. Introduction into the treatment of digoxin or glutamic acid smoothed over the cardiodepressive action of the drug. When administered continuously in a dose of 150-300 mg/day, ethacizine is an effective antiarrhythmic drug.
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The use of combined physiotherapy methods in 65 patients suffering of vegetative-vascular dystonias resulted in an improvement of the clinical data, normalization or improvement of electroencephalographic, rheovasographic and thermovision indices.
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Sixty-two craniovertebral dysplasy patients could be divided into three groups with respect to neurologic syndromes displaying disorders at different levels in a neurologic and X-rays investigation. The authors stress the diagnostic importance of a purposeful X-ray investigation of craniovertebral area in cases of neurologic symptoms and external signs of dysplasy, and the value of timely diagnosis for prevention of neurologic complications.
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On the basis of neurological and electrophysiological examination of 43 patients with myasthenia as well as scintigraphy of the thymus in them, the authors consider variants of differentiated, pathogenetic, and correcting therapy of this disease.
Blood oxygen balance and acid-base equilibrium were studied in 22 Chuvash patients with hereditary erythrocytosis. Despite the lack of the anomalous types of hemoglobin in the given type of erythrocytosis a number of the patients showed secondary tissue hypoxia associated with hyperoxia of the peripheral venous blood. It is shown that tissues are capable of extracting oxygen from the blood. It is assumed that the development of tissue hypoxia in the patients is determined by a fall in the rate of oxygen diffussion from the capillaries to the tissues or by blood shunting via the arteriolo-venular anastomoses because of microcirculatory disorders. The lowering of hematocrit to the level close to normal with the aid of bloodlettings makes oxygen balance return to normal and reduces tissue hypoxia.
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On the basis of clinical, radiological, electromyographical and histochemical examinations the authors describe criteria of the severity and prognosis of myasthenia and show their significance in the selection of an adequate pathogenetically-substantiated therapy.
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In 77,9 +/- 3,5% of the children with an active phase of rheumatic fever, developing with a prevalent lesion of the heart and joints, symptoms of animal and vegetative nervous system lesions were found. The neurological symptoms correlated with changes of the brain bioelectrical activity. The authors point to some dynamics of symptoms under the influence of anti-rheumatic treatment. Normalization of the brain bioelectrical activity, a regress of symptoms of the vegetative nervous system and muscular hypotonia are somewhat behind the clinical recovery. The existence of pathological activity on the EEG in children after an arrest of clinical symptoms of rheumatic fever may indicate to the possible subsequent development of chorea, the diencephalic syndrome, cerebrasthenic syndrome in these children.
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