Significance of blood flow in calculations of temperature in laser irradiated tissue.
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Biomedical subjects
Publications and source records attributed to L A Priebe.
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The transmittance of the ocular media has been measured in vivo in rabbit eyes using an argon laser light source and microthermocouple sensor. The intensity profiles at the cornea and retina were measured with the thermocouple and the ratio of the power associated with the intensity profiles indicated the fraction of light power reaching the retina. Measurements from 10 rabbits indicated a transmittance coefficient of 0.85 for wavelengths between 488 and 514.5 nm.
Fundus temperatures of the rhesus monkey were measured with argon laser (488 nm) irradiations that produced minimal, ophthalmoscopically visible lesions five minutes after exposure. Measurements were made with 10- to 20-mu tip diameter, copper-nickel thermocouples. Preliminary data included measurements at eight paramacular sites and seven macular sites. The threshold temperature rise was 17 to 26 degrees C for a ten-second exposure at these sites. Decreasing the exposure duration to 20 msec increased the threshold temperature rise range to the interval between 30 and 40 degrees C. The temperature measurements in the eye were compared to a computer solution of the heat conduction equation.
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