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Biomedical subjects

L A Rodríguez Toves

Publications and source records attributed to L A Rodríguez Toves.

11 recordsLinked to original sources
PubMed2002

[A study of spontaneous regeneration of defected short nerve gaps in rats].

Nerve trunk gaps can be repaired with different anastomosis methods. We investigate if spontaneous regeneration can yield results similar to artificial repair, and have compared the degree of nerve regeneration in nerve defects of extratemporal facial nerve trunk in Wistar rats. The lesions measured 4 millimeters long. Three groups were studied: 0. Normal nerve (control). 1. No treatment (therapeutic abstention). 2. Autografts. The considered parameters were: clinical outcome (degree of postoperative facial function, aspect of the defectuous region, nerve conduction latency, and number of axons that managed to penetrate the defect as well as their morphometric characteristics (nerve area). Our conclusion is that in this model placement of autografts yielded significantly better results in all the parameters studied, in spite of the scant defect length. These results likewise allow us to use this model to compare repair by means of different graft types.

Animals↗
PubMed2001

[Repair of facial nerve gaps with cryopreserved allografts in rats immunosuppressed with cyclosporin A].

UNLABELLED: The aim of this study is to assess the feasibility of peripheral nerve allografts pretreated utilizing cold storage and cyclosporin A to improve the facial nerve regeneration in Wistar rat. Three groups were designed: Normal Wistar rats. 4 millimeters nerve gaps repaired with cryopreserved nerve allografts. 4 millimeters nerve gaps repaired with cryopreserved nerve grafts and treated with cyclosporin A. At 16 weeks post-engraftment the animals were evaluated: Facial palsy grading system. Electrophysiologic latency. Axonal counting. Nervous fiber area immediately distal to the graft. The facial function of the experimental groups was similar to the control rats while the latency and morphometric parameters was poor than the normal rats. CONCLUSIONS: 1. Cryopreserved nerve allografts in facial nerve repair in rats are useful in the aquisition of a facial functional nerve recovery as much in immunosuppressed animal as not. 2. Cryopreservation of nerve allografts results a good method of storage of nerve grafts. 3. Cyclosporin A immunosuppression improved not much the grading facial palsy in this model but the electrophysiologic and morphometry is significantly better.

Anastomosis, Surgical↗
PubMed2001

[Effects of chronic alcohol drinking on rat's prostate. Experimental study].

OBJECTIVE: We have studies both the morphologic and morphometric modifications that the alcohol induces in subjected rats to chronic intake of alcohol and to evaluate the reversibility of this alterations after suppressing the ingesta of alcohol. MATERIAL AND METHODS: The animals underwent diverse outlines of chronic intake of alcohol and diverse morphometric parameters of the prostate were valued at the level of optic microscopy. RESULTS: Two morphologic prostatic patterns was observed according to the studied group of animals (experimental or control). It seems to be that the dose of alcohol was the factor that more it influenced in the morphometric variations of the cells.

Alcoholism↗
PubMed2001

[Cryopreservation of neural allografts for the nerve reconstruction in experimental surgery].

The possibility of clinical employment of nervous allografts depends on the likehood of its storage and also of the need of decreasing its antigenecity. We report our methodology for cryo-preservation and storage of nervous grafts, in view of animal experimentation as well as a re-examination of other methods in order to remember grafts storages done in previous epochs.

Animals↗
PubMed1998

[Testicular epidermoid cyst].

Epidermoid cysts are benign tumours that can affect testicles. Incidence is rare, having been described until now in less than 200 cases. Contribution of one study case of testicular epidermoid cyst and discussion of issues on histogenesis, ultrasound diagnosis and therapy approaches.

Adult↗
PubMed1998

[Morphometric correlation at the experimental level of renogram with renal arterial stenosis].

RATIONALE: A reduction of the renal size seen with the nephrogram (intravenous urography) has been described in renal artery stenosis. Such reduction, however, has not been quantified and the evolution is unknown in terms of duration of stenosis evolution. METHODS: Experimental study in rats which underwent controlled stenosis of a renal artery, with evaluation, using planimetry of the area and perimeter of the nephrogram, of the consequences such stenosis had at different observation intervals (30, 90 and 180 days). The effects of the stenosis relative to the duration of the experiment is also evaluated. RESULTS: The area and perimeter of the nephrogram become reduced in kidneys with artery stenosis. Besides, this reduction increases over time. CONCLUSION: The area and perimeter of the nephrogram are a useful method to study renal artery stenosis in rats.

Analysis of Variance↗
PubMed1997

[Testicular changes produced by alcohol].

Acting as a direct toxic through different mechanisms, alcohol causes many hormonal changes which induce sexual function impairment and fertility problems. We have used 36 white Wistar Lewis rats, divided in three large groups: 10% alcoholic, 25% alcoholic and control group for 55 and 95 days. The parameters studied were the rat's ponderal evolution, testicular volume and weight, testes and body weights ratio, as well as testes density and seminiferous tubule area. We found a decreased ponderal gain in animals receiving high doses of alcohol. Decreased testicular volume and increased density in long-term alcohol regime. At high dose and medium-term increased testicular weights were seen as compared to total weight of the rat. The area of the seminiferous tubule is reduced in all alcoholic groups.

Animals↗
PubMed1997

[Paratesticular lipoma].

In spite of being the most frequent benign tumour of the spermatic cord, absolute frequency of this neoplasia is very low. We discuss here a case report of an spermatic cord lipoma with several years evolution. Although ultrasound is useful for clinical diagnosis, exploratory scrototomy and surgical exeresis of the mass is the only reliable diagnosis and viable treatment.

Aged↗
PubMed1992

[Prostatic melanosis].

Melanin presence in the prostate can be accurately localized in epithelial cells (nevus) or in the stroma (prostatic melanosis). This article describes a new case and compiles all recorded cases as well as the theories concerning their origin.

Aged↗
PubMedDate not supplied

[Renal hydatidosis. Our experience].

Presentation of five cases of renal hydatidic cysts. Revision of literature with regard to their clinical presentation form, diagnostic methods and surgical approach for management.

Adult↗